Selective ion permeation involves complexation with carboxylates and lysine in a model human sodium channel

Structures of closed and open states of a voltage-gated sodium channel

(2017) Michael J. Lenaeus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution

(2017) Huaizong Shen et al.   SCIENCE

The complete structure of an activated open sodium channel

(2017) Altin Sula et al.   Nature Communications

A selectivity filter at the intracellular end of the acid-sensing ion channel pore

(2017) Timothy Lynagh et al.   eLife

Lysine and the Na+/K+ Selectivity in Mammalian Voltage-Gated Sodium Channels

(2016) Yang Li et al.   PLoS One

The hitchhiker’s guide to the voltage-gated sodium channel galaxy

(2015) Christopher A. Ahern et al.   JOURNAL OF GENERAL PHYSIOLOGY

Bacterial Voltage-Gated Sodium Channels (BacNaVs) from the Soil, Sea, and Salt Lakes Enlighten Molecular Mechanisms of Electrical Signaling and Pharmacology in the Brain and Heart

(2015) Jian Payandeh et al.   JOURNAL OF MOLECULAR BIOLOGY

Effects of the Protonation States of the EEEE Motif of a Bacterial Na+-Channel on Conduction and Pore Structure

(2015) Carmen Domene et al.   BIOPHYSICAL JOURNAL

Mechanism of Ion Permeation in Mammalian Voltage-Gated Sodium Channels

(2015) Somayeh Mahdavi et al.   PLoS One

Ion Selectivity Strategies of Sodium Channel Selectivity Filters

(2014) Todor Dudev et al.   ACCOUNTS OF CHEMICAL RESEARCH

Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy

(2014) Rocio K. Finol-Urdaneta et al.   JOURNAL OF GENERAL PHYSIOLOGY

Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism

(2014) C. Bagneris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ion conduction and conformational flexibility of a bacterial voltage-gated sodium channel

(2014) Céline Boiteux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different Inward and Outward Conduction Mechanisms in NaVMs Suggested by Molecular Dynamics Simulations

(2014) Song Ke et al.   PLoS Computational Biology

The Mechanism of Na+/K+ Selectivity in Mammalian Voltage-Gated Sodium Channels Based on Molecular Dynamics Simulation

(2013) Mengdie Xia et al.   BIOPHYSICAL JOURNAL

Structure of a Prokaryotic Sodium Channel Pore Reveals Essential Gating Elements and an Outer Ion Binding Site Common to Eukaryotic Channels

(2013) David Shaya et al.   JOURNAL OF MOLECULAR BIOLOGY

Conduction in a Biological Sodium Selective Channel

(2013) Letícia Stock et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state

(2013) Ryuta Kanai et al.   NATURE

Structural basis for Ca2+ selectivity of a voltage-gated calcium channel

(2013) Lin Tang et al.   NATURE

Small-molecule ligand docking into comparative models with Rosetta

(2013) Steven A Combs et al.   Nature Protocols

Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel

(2013) M. B. Ulmschneider et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catalysis of Na+ permeation in the bacterial sodium channel NaVAb

(2013) N. Chakrabarti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ion solvation and structural stability in a sodium channel investigated by molecular dynamics calculations

(2012) Hu Qiu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Analysis of the selectivity filter of the voltage-gated sodium channel NavRh

(2012) Xu Zhang et al.   CELL RESEARCH

Local anesthetic inhibition of a bacterial sodium channel

(2012) Sora Lee et al.   JOURNAL OF GENERAL PHYSIOLOGY

Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel

(2012) Xu Zhang et al.   NATURE

Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing

(2012) Emily C. McCusker et al.   Nature Communications

On Conduction in a Bacterial Sodium Channel

(2012) Simone Furini et al.   PLoS Computational Biology

NaChBac: The Long Lost Sodium Channel Ancestor

(2011) Kalypso Charalambous et al.   BIOCHEMISTRY

Sodium Ion Binding Sites and Hydration in the Lumen of a Bacterial Ion Channel from Molecular Dynamics Simulations

(2011) Vincenzo Carnevale et al.   Journal of Physical Chemistry Letters

Mechanism of Ion Permeation and Selectivity in a Voltage Gated Sodium Channel

(2011) Ben Corry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Large shifts in pKa values of lysine residues buried inside a protein

(2011) D. G. Isom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring the Ion Selectivity Properties of a Large Number of Simplified Binding Site Models

(2010) Benoît Roux   BIOPHYSICAL JOURNAL

Factors Governing the Na+vs K+Selectivity in Sodium Ion Channels

(2010) Todor Dudev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Reinterpreting the Anomalous Mole Fraction Effect: The Ryanodine Receptor Case Study

(2009) Dirk Gillespie et al.   BIOPHYSICAL JOURNAL

Subtype-selective targeting of voltage-gated sodium channels

(2009) Steve England et al.   BRITISH JOURNAL OF PHARMACOLOGY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The Anomalous Mole Fraction Effect in Calcium Channels: A Measure of Preferential Selectivity

(2008) Dirk Gillespie et al.   BIOPHYSICAL JOURNAL