Modeling Within-Host Effects of Drugs on Plasmodium falciparum Transmission and Prospects for Malaria Elimination

The Stability of Malaria Elimination

(2013) C. Chiyaka et al.   SCIENCE

Eliminating Malaria

(2013) D. A. Fidock   SCIENCE

Malaria's Missing Number: Calculating the Human Component of R0 by a Within-Host Mechanistic Model of Plasmodium falciparum Infection and Transmission

(2013) Geoffrey L. Johnston et al.   PLoS Computational Biology

Improving Pharmacokinetic-Pharmacodynamic Modeling to Investigate Anti-Infective Chemotherapy with Application to the Current Generation of Antimalarial Drugs

(2013) Katherine Kay et al.   PLoS Computational Biology

The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector

(2012) J. C. van Pelt-Koops et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Effect of Primaquine on Gametocyte Development and Clearance in the Treatment of Uncomplicated Falciparum Malaria With Dihydroartemisinin-Piperaquine in South Sumatra, Western Indonesia: An Open-Label, Randomized, Controlled Trial

(2012) Inge Sutanto et al.   CLINICAL INFECTIOUS DISEASES

Global malaria mortality between 1980 and 2010: a systematic analysis

(2012) Christopher JL Murray et al.   LANCET

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

(2012) Aung Pyae Phyo et al.   LANCET

Primaquine to prevent transmission of falciparum malaria

(2012) Nicholas J White   LANCET INFECTIOUS DISEASES

Funding for malaria control 2006–2010: A comprehensive global assessment

(2012) David M Pigott et al.   MALARIA JOURNAL

Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common

(2012) Nicholas J White et al.   MALARIA JOURNAL

Haemolysis risk in methylene blue treatment of G6PD-sufficient and G6PD-deficient West-African children with uncomplicated falciparum malaria: a synopsis of four RCTs

(2012) Olaf Müller et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Mathematical Modeling of Malaria Infection with Innate and Adaptive Immunity in Individuals and Agent-Based Communities

(2012) David Gurarie et al.   PLoS One

Optimising Strategies for Plasmodium falciparum Malaria Elimination in Cambodia: Primaquine, Mass Drug Administration and Artemisinin Resistance

(2012) Richard J. Maude et al.   PLoS One

Ensemble Modeling of the Likely Public Health Impact of a Pre-Erythrocytic Malaria Vaccine

(2012) Thomas Smith et al.   PLOS MEDICINE

The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites

(2012) Michael Delves et al.   PLOS MEDICINE

Hitting Hotspots: Spatial Targeting of Malaria for Control and Elimination

(2012) Teun Bousema et al.   PLOS MEDICINE

Development, Evaluation, and Application of anIn SilicoModel for Antimalarial Drug Treatment and Failure

(2011) Katherine Winter et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Epidemiology and Infectivity of Plasmodium falciparum and Plasmodium vivax Gametocytes in Relation to Malaria Control and Elimination

(2011) T. Bousema et al.   CLINICAL MICROBIOLOGY REVIEWS

Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study

(2011) Jean-François Trape et al.   LANCET INFECTIOUS DISEASES

A new world malaria map: Plasmodium falciparum endemicity in 2010

(2011) Peter W Gething et al.   MALARIA JOURNAL

The Threat of Artemisinin-Resistant Malaria

(2011) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

(2011) S. H. Adjalley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solving the Sisyphean Problem of Malaria in Zanzibar

(2011) D. L. Smith et al.   SCIENCE

A Research Agenda for Malaria Eradication: Modeling

(2011)   PLOS MEDICINE

New Fixed-Dose Artesunate-Mefloquine Formulation against Multidrug-Resistant Plasmodium falciparum in Adults: a Comparative Phase IIb Safety and Pharmacokinetic Study with Standard-Dose Nonfixed Artesunate plus Mefloquine

(2010) S. Krudsood et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Low infectivity of Plasmodium falciparum gametocytes to Anopheles gambiae following treatment with sulfadoxine–pyrimethamine in Mali

(2010) Abdoul H. Beavogui et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Sulfadoxine–pyrimethamine impairs Plasmodium falciparum gametocyte infectivity and Anopheles mosquito survival

(2010) Aminatou Kone et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Costs and financial feasibility of malaria elimination

(2010) Oliver Sabot et al.   LANCET

Call to action: priorities for malaria elimination

(2010) Richard GA Feachem et al.   LANCET

Ranking of elimination feasibility between malaria-endemic countries

(2010) Andrew J Tatem et al.   LANCET

Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial

(2010) Frank Smithuis et al.   LANCET INFECTIOUS DISEASES

How absolute is zero? An evaluation of historical and current definitions of malaria elimination

(2010) Justin M Cohen et al.   MALARIA JOURNAL

Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs

(2010) Teun Bousema et al.   MALARIA JOURNAL

Estimating the Global Clinical Burden of Plasmodium falciparum Malaria in 2007

(2010) Simon I. Hay et al.   PLOS MEDICINE

Reducing Plasmodium falciparum Malaria Transmission in Africa: A Model-Based Evaluation of Intervention Strategies

(2010) Jamie T. Griffin et al.   PLOS MEDICINE

Submicroscopic Infection inPlasmodium falciparum–Endemic Populations: A Systematic Review and Meta‐Analysis

(2009) Lucy C. Okell et al.   JOURNAL OF INFECTIOUS DISEASES

Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria

(2009) Julie Gutman et al.   MALARIA JOURNAL

Endemicity response timelines for Plasmodium falciparum elimination

(2009) David L Smith et al.   MALARIA JOURNAL

Optimally timing primaquine treatment to reduce Plasmodium falciparum transmission in low endemicity Thai-Myanmar border populations

(2009) Saranath Lawpoolsri et al.   MALARIA JOURNAL

New medicines to improve control and contribute to the eradication of malaria

(2009) Timothy N. C. Wells et al.   NATURE REVIEWS DRUG DISCOVERY

Primaquine revisited six decades after its discovery

(2008) Nuno Vale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Malaria: progress, perils, and prospects for eradication

(2008) Brian M. Greenwood et al.   JOURNAL OF CLINICAL INVESTIGATION

A new global malaria eradication strategy

(2008) Richard Feachem et al.   LANCET

Access to artemisinin combination therapy for malaria in remote areas of Cambodia

(2008) Shunmay Yeung et al.   MALARIA JOURNAL

The role of anti-malarial drugs in eliminating malaria

(2008) Nicholas J White   MALARIA JOURNAL

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials

(2008) Lucy C Okell et al.   MALARIA JOURNAL

Problems with continuous-time malaria models in describing gametocytogenesis

(2008) L. CROOKS   PARASITOLOGY

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE