The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector

A High-Throughput Screen Targeting Malaria Transmission Stages Opens New Avenues for Drug Development

(2011) Kathrin Buchholz et al.   JOURNAL OF INFECTIOUS DISEASES

A malaria gametocytocidal assay using oxidoreduction indicator, alamarBlue

(2011) Takeshi Q Tanaka et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

(2011) S. H. Adjalley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Research Agenda to Underpin Malaria Eradication

(2011) Pedro L. Alonso et al.   PLOS MEDICINE

In Tanzania, Hemolysis after a Single Dose of Primaquine Coadministered with an Artemisinin Is Not Restricted to Glucose-6-Phosphate Dehydrogenase-Deficient (G6PD A-) Individuals

(2010) S. A. Shekalaghe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sulfadoxine–pyrimethamine impairs Plasmodium falciparum gametocyte infectivity and Anopheles mosquito survival

(2010) Aminatou Kone et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

(2010) Bryan K. S. Yeung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Flow cytometry for the evaluation of anti-plasmodial activity of drugs on Plasmodium falciparum gametocytes

(2010) Severine Chevalley et al.   MALARIA JOURNAL

Malaria gametocytogenesis

(2010) David A. Baker   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

In vitrosensitivity ofPlasmodium falciparumto conventional and novel antimalarial drugs in Papua New Guinea

(2010) Rina P. M. Wong et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Effect of Antimalarial Drugs onPlasmodium falciparumGametocytes

(2009) Christopher L. Peatey et al.   JOURNAL OF INFECTIOUS DISEASES

Understanding the pharmacokinetics of Coartem®

(2009) Abdoulaye Djimdé et al.   MALARIA JOURNAL

New medicines to improve control and contribute to the eradication of malaria

(2009) Timothy N. C. Wells et al.   NATURE REVIEWS DRUG DISCOVERY

Primaquine revisited six decades after its discovery

(2008) Nuno Vale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The role of anti-malarial drugs in eliminating malaria

(2008) Nicholas J White   MALARIA JOURNAL

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials

(2008) Lucy C Okell et al.   MALARIA JOURNAL

A green fluorescent protein-based assay for determining gametocyte production in Plasmodium falciparum

(2008) M DIXON et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY