Effect of Dedifferentiation on Time to Mutation Acquisition in Stem Cell-Driven Cancers

Pathways to Tumorigenesis—Modeling Mutation Acquisition in Stem Cells and Their Progeny

(2015) Rina Ashkenazi et al.   NEOPLASIA

Cancer stem cells: The challenges ahead

(2013) Jan Paul Medema   NATURE CELL BIOLOGY

Symmetric vs. Asymmetric Stem Cell Divisions: An Adaptation against Cancer?

(2013) Leili Shahriyari et al.   PLoS One

Direct reprogramming by oncogenic Ras and Myc

(2013) I. Ischenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Dependent Transition from Cell-Level to Population-Level Control in Murine Intestinal Homeostasis Revealed by Coalescence Analysis

(2013) Zheng Hu et al.   PLoS Genetics

On the Probability of Random Genetic Mutations for Various Types of Tumor Growth

(2012) Cristian Tomasetti   BULLETIN OF MATHEMATICAL BIOLOGY

Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

(2012) Sarah Schwitalla et al.   CELL

Defining the mode of tumour growth by clonal analysis

(2012) Gregory Driessens et al.   NATURE

The replication rate of human hematopoietic stem cells in vivo

(2011) S. N. Catlin et al.   BLOOD

The individuality of stem cells

(2011) Arthur D Lander   BMC BIOLOGY

Stochastic dynamics and the evolution of mutations in stem cells

(2011) David Dingli et al.   BMC BIOLOGY

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

(2011) Nicolas Goardon et al.   CANCER CELL

Strategies for Homeostatic Stem Cell Self-Renewal in Adult Tissues

(2011) Benjamin D. Simons et al.   CELL

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma

(2011) Chong Liu et al.   CELL

Universal patterns of stem cell fate in cycling adult tissues

(2011) A. M. Klein et al.   DEVELOPMENT

Intratumor Heterogeneity in Evolutionary Models of Tumor Progression

(2011) Rick Durrett et al.   GENETICS

Extinction models for cancer stem cell therapy

(2011) Mary Sehl et al.   MATHEMATICAL BIOSCIENCES

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

Spatial structure increases the waiting time for cancer

(2011) Erik A Martens et al.   NEW JOURNAL OF PHYSICS

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Structured Population Model of Cell Differentiation

(2011) Marie Doumic et al.   SIAM JOURNAL ON APPLIED MATHEMATICS

Somatic mutations and the hierarchy of hematopoiesis

(2010) Arne Traulsen et al.   BIOESSAYS

Selection in spatial stochastic models of cancer: Migration as a key modulator of fitness

(2010) Craig J Thalhauser et al.   Biology Direct

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal

(2010) Z. Zhao et al.   GENES & DEVELOPMENT

Some Consequences of Demographic Stochasticity in Population Genetics

(2010) T. L. Parsons et al.   GENETICS

The Therapeutic Implications of Plasticity of the Cancer Stem Cell Phenotype

(2010) Kevin Leder et al.   PLoS One

Role of symmetric and asymmetric division of stem cells in developing drug resistance

(2010) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accumulation of driver and passenger mutations during tumor progression

(2010) I. Bozic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift

(2010) C. Lopez-Garcia et al.   SCIENCE

A waiting time problem arising from the study of multi-stage carcinogenesis

(2009) Rick Durrett et al.   ANNALS OF APPLIED PROBABILITY

Evolutionary Theory of Cancer

(2009) Camille Stephan-Otto Attolini et al.   Annals of the New York Academy of Sciences

Differential Destruction of Stem Cells: Implications for Targeted Cancer Stem Cell Therapy

(2009) M. E. Sehl et al.   CANCER RESEARCH

The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

(2009) Angelo Cicalese et al.   CELL

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

A progenitor cell origin of myeloid malignancies

(2009) H. Haeno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Lineages and the Logic of Proliferative Control

(2009) Arthur D Lander et al.   PLOS BIOLOGY

Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells

(2008) Zeng-Jie Yang et al.   CANCER CELL

Genomic Instability and Carcinogenesis: An Update

(2008) Wael Abdel-Rahman   CURRENT GENOMICS

The fixation probability of beneficial mutations

(2008) Z Patwa et al.   Journal of the Royal Society Interface

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

(2008) Timothy J. Ley et al.   NATURE

Multiple mutant clones in blood rarely coexist

(2008) David Dingli et al.   PHYSICAL REVIEW E

Neutral evolution in paroxysmal nocturnal hemoglobinuria

(2008) D. Dingli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative lesion sequencing provides insights into tumor evolution

(2008) S. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling of Asymmetric Cell Division in Hematopoietic Stem Cells—Regulation of Self-Renewal Is Essential for Efficient Repopulation

(2008) Anna Marciniak-Czochra et al.   STEM CELLS AND DEVELOPMENT

Absorption and fixation times for neutral and quasi-neutral populations with density dependence

(2008) Todd L. Parsons et al.   THEORETICAL POPULATION BIOLOGY