A New Model for Pore Formation by Cholesterol-Dependent Cytolysins

The multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) high performance computing infrastructure: applications in neuroscience and neuroinformatics research

(2014) Wojtek J. Goscinski et al.   Frontiers in Neuroinformatics

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Disulfide-bond scanning reveals assembly state and β-strand tilt angle of the PFO β-barrel

(2013) Takehiro K Sato et al.   Nature Chemical Biology

Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism

(2013) Matteo T Degiacomi et al.   Nature Chemical Biology

Predicting giant transmembrane β-barrel architecture

(2012) Cyril F. Reboul et al.   BIOINFORMATICS

Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins

(2012) Michelle A Dunstone et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Identification and Characterization of the First Cholesterol-Dependent Cytolysins from Gram-Negative Bacteria

(2012) Eileen M. Hotze et al.   INFECTION AND IMMUNITY

Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC)

(2012) Alexander E. Aleshin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monomer-Monomer Interactions Propagate Structural Transitions Necessary for Pore Formation by the Cholesterol-dependent Cytolysins

(2012) Eileen M. Hotze et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of oligomeric state through geometric coupling of protein interfaces

(2012) T. Perica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane assembly of the cholesterol-dependent cytolysin pore complex

(2011) Eileen M. Hotze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

ProDy: Protein Dynamics Inferred from Theory and Experiments

(2011) A. Bakan et al.   BIOINFORMATICS

Stereochemical errors and their implications for molecular dynamics simulations

(2011) Eduard Schreiner et al.   BMC BIOINFORMATICS

Structure-guided Antigen Engineering Yields Pneumolysin Mutants Suitable for Vaccination against Pneumococcal Disease

(2011) Eliud O. Oloo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Symmetry-Restrained Flexible Fitting for Symmetric EM Maps

(2011) Kwok-Yan Chan et al.   STRUCTURE

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

MUSTANG-MR Structural Sieving Server: Applications in Protein Structural Analysis and Crystallography

(2010) Arun S. Konagurthu et al.   PLoS One

Crystal structure of cytotoxin protein suilysin from Streptococcus suis

(2010) Lingfeng Xu et al.   Protein & Cell

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes

(2009) Sunhwan Jo et al.   BIOPHYSICAL JOURNAL

Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted byBacillus anthracis

(2009) Raymond W. Bourdeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its Family

(2009) Gregory D. Friedland et al.   PLoS Computational Biology

The MACPF/CDC family of pore-forming toxins

(2008) Carlos J. Rosado et al.   CELLULAR MICROBIOLOGY

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE