Human Dominant Disease Genes Are Enriched in Paralogs Originating from Whole Genome Duplication

On the retention of gene duplicates prone to dominant deleterious mutations

(2014) Giulia Malaguti et al.   THEORETICAL POPULATION BIOLOGY

Human Monogenic Disease Genes Have Frequently Functionally Redundant Paralogs

(2013) Wei-Hua Chen et al.   PLoS Computational Biology

Younger Genes Are Less Likely to Be Essential than Older Genes, and Duplicates Are Less Likely to Be Essential than Singletons of the Same Age

(2012) W.-H. Chen et al.   MOLECULAR BIOLOGY AND EVOLUTION

On the Expansion of “Dangerous” Gene Repertoires by Whole-Genome Duplications in Early Vertebrates

(2012) Param Priya Singh et al.   Cell Reports

Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates

(2012) M. Tinti et al.   Open Biology

On the Origins of Mendelian Disease Genes in Man: The Impact of Gene Duplication

(2011) J. E. Dickerson et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse

(2011) J. T. Eppig et al.   NUCLEIC ACIDS RESEARCH

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Ohnologs in the human genome are dosage balanced and frequently associated with disease

(2010) T. Makino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EVOLUTION FROM FISH TO MAMMALS BY GENE DUPLICATION

(2009) SUSUMU OHNO et al.   HEREDITAS

The complex relationship of gene duplication and essentiality

(2009) Takashi Makino et al.   TRENDS IN GENETICS

Natural Selection on Genes that Underlie Human Disease Susceptibility

(2008) Ran Blekhman et al.   CURRENT BIOLOGY

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

(2008) A. J. Vilella et al.   GENOME RESEARCH

Predicting the Proportion of Essential Genes in Mouse Duplicates Based on Biased Mouse Knockout Genes

(2008) Zhixi Su et al.   JOURNAL OF MOLECULAR EVOLUTION

The amphioxus genome and the evolution of the chordate karyotype

(2008) Nicholas H. Putnam et al.   NATURE

Role of Duplicate Genes in Robustness against Deleterious Human Mutations

(2008) Tzu-Lin Hsiao et al.   PLoS Genetics