A General Model for Toxin-Antitoxin Module Dynamics Can Explain Persister Cell Formation in E. coli

Modeling Gene Expression in Time and Space

(2013) Pau Rué et al.   Annual Review of Biophysics

Energetic Basis of Uncoupling Folding from Binding for an Intrinsically Disordered Protein

(2013) Igor Drobnak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bacterial Persistence and Toxin-Antitoxin Loci

(2012) Kenn Gerdes et al.   Annual Review of Microbiology

Modeling suggests that gene circuit architecture controls phenotypic variability in a bacterial persistence network

(2012) Rachel S Koh et al.   BMC Systems Biology

Conditional cooperativity in toxin–antitoxin regulation prevents random toxin activation and promotes fast translational recovery

(2012) Ilaria Cataudella et al.   NUCLEIC ACIDS RESEARCH

Regulation of Enteric vapBC Transcription: Induction by VapC Toxin Dimer-Breaking

(2012) Kristoffer S. Winther et al.   NUCLEIC ACIDS RESEARCH

Additional role for the ccd operon of F-plasmid as a transmissible persistence factor

(2012) A. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Crystal Structure of the Intact E. coli RelBE Toxin-Antitoxin Complex Provides the Structural Basis for Conditional Cooperativity

(2012) Andreas Bøggild et al.   STRUCTURE

Mapping the Environmental Fitness Landscape of a Synthetic Gene Circuit

(2012) Dmitry Nevozhay et al.   PLoS Computational Biology

Selective Translation of Leaderless mRNAs by Specialized Ribosomes Generated by MazF in Escherichia coli

(2011) Oliver Vesper et al.   CELL

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

Bacterial persistence by RNA endonucleases

(2011) Etienne Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allostery and Intrinsic Disorder Mediate Transcription Regulation by Conditional Cooperativity

(2010) Abel Garcia-Pino et al.   CELL

Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence

(2010) Eitan Rotem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems

(2010) Mark A. Arbing et al.   STRUCTURE

The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE

(2009) Cajetan Neubauer et al.   CELL

Growth Rate-Dependent Global Effects on Gene Expression in Bacteria

(2009) Stefan Klumpp et al.   CELL

RelB and RelE of Escherichia coli Form a Tight Complex That Represses Transcription via the Ribbon–Helix–Helix Motif in RelB

(2009) Martin Overgaard et al.   JOURNAL OF MOLECULAR BIOLOGY

Rejuvenation of CcdB-Poisoned Gyrase by an Intrinsically Disordered Protein Domain

(2009) Natalie De Jonge et al.   MOLECULAR CELL

Emergent bistability by a growth-modulating positive feedback circuit

(2009) Cheemeng Tan et al.   Nature Chemical Biology

Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB

(2009) M. A. Schumacher et al.   SCIENCE

Structural Mechanism of Transcriptional Autorepression of the Escherichia coli RelB/RelE Antitoxin/Toxin Module

(2008) Guang-Yao Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Messenger RNA interferase RelE controlsrelBEtranscription by conditional cooperativity

(2008) Martin Overgaard et al.   MOLECULAR MICROBIOLOGY