Synthetic Lethality between Gene Defects Affecting a Single Non-essential Molecular Pathway with Reversible Steps

Delineation of Joint Molecule Resolution Pathways in Meiosis Identifies a Crossover-Specific Resolvase

(2012) Kseniya Zakharyevich et al.   CELL

BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism

(2012) Arnaud De Muyt et al.   MOLECULAR CELL

Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

(2012) Yogesh Kulathu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Uncovering Ubiquitin and Ubiquitin-like Signaling Networks

(2011) Alfred C. O. Vertegaal   CHEMICAL REVIEWS

Mechanisms and principles of N-linked protein glycosylation

(2011) Flavio Schwarz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Putting genetic interactions in context through a global modular decomposition

(2011) Jeremy Bellay et al.   GENOME RESEARCH

The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

(2011) Thomas Helleday   Molecular Oncology

Rad51 paralogues Rad55–Rad57 balance the antirecombinase Srs2 in Rad51 filament formation

(2011) Jie Liu et al.   NATURE

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Protein Complexes are Central in the Yeast Genetic Landscape

(2011) Magali Michaut et al.   PLoS Computational Biology

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

Mechanisms, regulation and consequences of protein SUMOylation

(2010) Kevin A. Wilkinson et al.   BIOCHEMICAL JOURNAL

Charting the genetic interaction map of a cell

(2010) Michael Costanzo et al.   CURRENT OPINION IN BIOTECHNOLOGY

Synthetic lethal interactions for the development of cancer therapeutics: biological and methodological advancements

(2010) Shinji Mizuarai et al.   HUMAN GENETICS

Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity

(2010) Sybille Schwendener et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

(2010) Anastasia Baryshnikova et al.   NATURE METHODS

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chaperone networks: Tipping the balance in protein folding diseases

(2010) Cindy Voisine et al.   NEUROBIOLOGY OF DISEASE

Rad52 inactivation is synthetically lethal with BRCA2 deficiency

(2010) Z. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rewiring of Genetic Networks in Response to DNA Damage

(2010) S. Bandyopadhyay et al.   SCIENCE

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

(2010) Robert B. Hamanaka et al.   TRENDS IN BIOCHEMICAL SCIENCES

Asymptotology of chemical reaction networks

(2009) A.N. Gorban et al.   CHEMICAL ENGINEERING SCIENCE

FANCJ Uses Its Motor ATPase to Destabilize Protein-DNA Complexes, Unwind Triplexes, and Inhibit RAD51 Strand Exchange

(2009) Joshua A. Sommers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities

(2009) Kasper Fugger et al.   JOURNAL OF CELL BIOLOGY

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing

(2009) K. J. McManus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Homologous recombination in DNA repair and DNA damage tolerance

(2008) Xuan Li et al.   CELL RESEARCH

The consequences of Rad51 overexpression for normal and tumor cells

(2008) Hannah L. Klein   DNA REPAIR

Quality control of DNA break metabolism: in the ‘end’, it's a good thing

(2008) Roland Kanaar et al.   EMBO JOURNAL

Profiling Essential Genes in Human Mammary Cells by Multiplex RNAi Screening

(2008) J. M. Silva et al.   SCIENCE

Functional Maps of Protein Complexes from Quantitative Genetic Interaction Data

(2008) Sourav Bandyopadhyay et al.   PLoS Computational Biology