A Sequential Vesicle Pool Model with a Single Release Sensor and a Ca2+-Dependent Priming Catalyst Effectively Explains Ca2+-Dependent Properties of Neurosecretion

Doc2b Synchronizes Secretion from Chromaffin Cells by Stimulating Fast and Inhibiting Sustained Release

(2013) P. S. Pinheiro et al.   JOURNAL OF NEUROSCIENCE

Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release

(2012) Jörg Malsam et al.   EMBO JOURNAL

Nonconserved Ca2+/Calmodulin Binding Sites in Munc13s Differentially Control Synaptic Short-Term Plasticity

(2012) N. Lipstein et al.   MOLECULAR AND CELLULAR BIOLOGY

Actin-dependent rapid recruitment of reluctant synaptic vesicles into a fast-releasing vesicle pool

(2012) J. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release

(2012) C. Ma et al.   SCIENCE

Doc2 Is a Ca2+ Sensor Required for Asynchronous Neurotransmitter Release

(2011) Jun Yao et al.   CELL

Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion

(2011) Zhao Wang et al.   JOURNAL OF CELL BIOLOGY

Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex

(2011) Cong Ma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion

(2011) Shyam S Krishnakumar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synaptotagmin Increases the Dynamic Range of Synapses by Driving Ca2+-Evoked Release and by Clamping a Near-Linear Remaining Ca2+ Sensor

(2011) Olexiy Kochubey et al.   NEURON

A Coiled Coil Trigger Site Is Essential for Rapid Binding of Synaptobrevin to the SNARE Acceptor Complex

(2010) Katrin Wiederhold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two distinct secretory vesicle–priming steps in adrenal chromaffin cells

(2010) Yuanyuan Liu et al.   JOURNAL OF CELL BIOLOGY

Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis

(2010) Alexander M. Walter et al.   JOURNAL OF CELL BIOLOGY

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

(2010) Ok-Ho Shin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complexin Clamps Asynchronous Release by Blocking a Secondary Ca2+ Sensor via Its Accessory α Helix

(2010) Xiaofei Yang et al.   NEURON

SNARE Protein Recycling by αSNAP and βSNAP Supports Synaptic Vesicle Priming

(2010) Andrea Burgalossi et al.   NEURON

Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction

(2010) H. Wen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modelling Vesicular Release at Hippocampal Synapses

(2010) Suhita Nadkarni et al.   PLoS Computational Biology

Synaptotagmin-1 Docks Secretory Vesicles to Syntaxin-1/SNAP-25 Acceptor Complexes

(2009) Heidi de Wit et al.   CELL

A General Model of Synaptic Transmission and Short-Term Plasticity

(2009) Bin Pan et al.   NEURON

Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation

(2009) J. F. Ellena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CAPS Facilitates Filling of the Rapidly Releasable Pool of Large Dense-Core Vesicles

(2008) Y. Liu et al.   JOURNAL OF NEUROSCIENCE

Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+

(2008) Michael C Chicka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multiple Roles of Calcium Ions in the Regulation of Neurotransmitter Release

(2008) Erwin Neher et al.   NEURON

Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells

(2008) J.-S. Schonn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis

(2008) A. Maximov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA