Posterior Association Networks and Functional Modules Inferred from Rich Phenotypes of Gene Perturbations

Phase I dose escalation study of the oral multi-CDK inhibitor PHA-848125

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(2011) Matthew Booker et al.   BMC GENOMICS

A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue

(2011) Rebecca A. Green et al.   CELL

An integrated approach to characterize genetic interaction networks in yeast metabolism

(2011) Balázs Szappanos et al.   NATURE GENETICS

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(2011) Thomas Horn et al.   NATURE METHODS

Chemical Probes of Escherichia coli Uncovered through Chemical-Chemical Interaction Profiling with Compounds of Known Biological Activity

(2010) Maya A. Farha et al.   CHEMISTRY & BIOLOGY

Delta-Like Ligand 4 Plays a Critical Role in Pericyte/Vascular Smooth Muscle Cell Formation during Vasculogenesis and Tumor Vessel Expansion in Ewing's Sarcoma

(2010) K. L. Schadler et al.   CLINICAL CANCER RESEARCH

Predicting genetic modifier loci using functional gene networks

(2010) I. Lee et al.   GENOME RESEARCH

RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma

(2010) Shilpi Arora et al.   Molecular Cancer

Automated identification of pathways from quantitative genetic interaction data

(2010) Alexis Battle et al.   Molecular Systems Biology

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(2010) Anastasia Baryshnikova et al.   NATURE METHODS

The BioGRID Interaction Database: 2011 update

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The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Angiogenesis and vascular targeting in Ewing sarcoma

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Genetic architecture of quantitative traits in mice, flies, and humans

(2009) J. Flint et al.   GENOME RESEARCH

ChIP-seq: Using high-throughput sequencing to discover protein–DNA interactions

(2009) Dominic Schmidt et al.   METHODS

GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update

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Finding friends and enemies in an enemies-only network: A graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions

(2008) Y. Qi et al.   GENOME RESEARCH

The art and design of genetic screens: RNA interference

(2008) Michael Boutros et al.   NATURE REVIEWS GENETICS

Defining genetic interaction

(2008) R. Mani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling synthetic lethality

(2008) Nolwenn Le Meur et al.   GENOME BIOLOGY