Tradeoff Between Stability and Multispecificity in the Design of Promiscuous Proteins

Folding and binding cascades: Dynamic landscapes and population shifts

(2010) Sandeep Kumar et al.   PROTEIN SCIENCE

Computational design of affinity and specificity at protein–protein interfaces

(2009) John Karanicolas et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Design of protein-interaction specificity gives selective bZIP-binding peptides

(2009) Gevorg Grigoryan et al.   NATURE

INTREPID: a web server for prediction of functionally important residues by evolutionary analysis

(2009) S. Sankararaman et al.   NUCLEIC ACIDS RESEARCH

Computational structure-based redesign of enzyme activity

(2009) C.-Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design, expression and characterization of mutants of fasciculin optimized for interaction with its target, acetylcholinesterase

(2009) O. Sharabi et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details

(2009) V. Potapov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

X-ray vs. NMR structures as templates for computational protein design

(2009) Michael Schneider et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Energetic determinants of protein binding specificity: Insights into protein interaction networks

(2009) Pablo Carbonell et al.   PROTEOMICS

A Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its Family

(2009) Gregory D. Friedland et al.   PLoS Computational Biology

A computational framework to empower probabilistic protein design

(2008) M. Fromer et al.   BIOINFORMATICS

Computational Design of Calmodulin Mutants with up to 900-Fold Increase in Binding Specificity

(2008) Eliyahu Yosef et al.   JOURNAL OF MOLECULAR BIOLOGY

Accurate prediction for atomic-level protein design and its application in diversifying the near-optimal sequence space

(2008) Menachem Fromer et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

BIOCHEMISTRY: How Do Proteins Interact?

(2008) D. D. Boehr et al.   SCIENCE

Computer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet Design

(2008) Xiaozhen Hu et al.   STRUCTURE

Prediction of Protein-Protein Interface Sequence Diversity Using Flexible Backbone Computational Protein Design

(2008) Elisabeth L. Humphris et al.   STRUCTURE

A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction

(2008) Jörg Gsponer et al.   STRUCTURE

How Protein Stability and New Functions Trade Off

(2008) Nobuhiko Tokuriki et al.   PLoS Computational Biology