Modeling Signal Propagation Mechanisms and Ligand-Based Conformational Dynamics of the Hsp90 Molecular Chaperone Full-Length Dimer

The Hsp90 molecular chaperone: an open and shut case for treatment

(2008) Laurence H. Pearl et al.   BIOCHEMICAL JOURNAL

Apo-Hsp90 coexists in two open conformational states in solution

(2008) Patrick Bron et al.   BIOLOGY OF THE CELL

Coevolution of Function and the Folding Landscape: Correlation with Density of Native Contacts

(2008) Ronald D. Hills et al.   BIOPHYSICAL JOURNAL

Mechanism of Signal Propagation upon Retinal Isomerization: Insights from Molecular Dynamics Simulations of Rhodopsin Restrained by Normal Modes

(2008) Basak Isin et al.   BIOPHYSICAL JOURNAL

A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s

(2008) Cara K. Vaughan et al.   FEBS Journal

The Human Cdc37·Hsp90 Complex Studied by Heteronuclear NMR Spectroscopy

(2008) Sridhar Sreeramulu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intra- and Intermonomer Interactions Are Required to Synergistically Facilitate ATP Hydrolysis in Hsp90

(2008) Christian N. Cunningham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Studies on the Co-chaperone Hop and Its Complexes with Hsp90

(2008) S.C. Onuoha et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Dynamics Simulation of the Escherichia coli NikR Protein: Equilibrium Conformational Fluctuations Reveal Interdomain Allosteric Communication Pathways

(2008) Michael J. Bradley et al.   JOURNAL OF MOLECULAR BIOLOGY

Coupling between global dynamics and signal transduction pathways: a mechanism of allostery for chaperonin GroEL

(2008) Chakra Chennubhotla et al.   Molecular BioSystems

Species-Dependent Ensembles of Conserved Conformational States Define the Hsp90 Chaperone ATPase Cycle

(2008) Daniel R. Southworth et al.   MOLECULAR CELL

Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution

(2008) G. Colombo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution

(2008) O. F. Lange et al.   SCIENCE

Multiple Conformations of E. coli Hsp90 in Solution: Insights into the Conformational Dynamics of Hsp90

(2008) Kristin A. Krukenberg et al.   STRUCTURE