Site-Directed Spin Labeling Reveals Pentameric Ligand-Gated Ion Channel Gating Motions

Nicotinic Receptor Transduction Zone: Invariant Arginine Couples to Multiple Electron-Rich Residues

(2013) Nuriya Mukhtasimova et al.   BIOPHYSICAL JOURNAL

Structural Sensitivity of a Prokaryotic Pentameric Ligand-gated Ion Channel to Its Membrane Environment

(2013) Jonathan M. Labriola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Propofol Binding to the Resting State of theGloeobacter violaceusLigand-gated Ion Channel (GLIC) Induces Structural Changes in the Inter- and Intrasubunit Transmembrane Domain (TMD) Cavities

(2013) Borna Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gating of Pentameric Ligand-Gated Ion Channels: Structural Insights and Ambiguities

(2013) Corrie J.B. daCosta et al.   STRUCTURE

Function of Shaker potassium channels produced by cell-free translation upon injection into Xenopus oocytes

(2013) Brian W. Jarecki et al.   Scientific Reports

Desensitization Mechanism in Prokaryotic Ligand-gated Ion Channel

(2012) Phanindra Velisetty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Transitions Underlying Pore Opening and Desensitization in Membrane-embeddedGloeobacter violaceusLigand-gated Ion Channel (GLIC)

(2012) Phanindra Velisetty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing

(2012) Nigel Unwin et al.   JOURNAL OF MOLECULAR BIOLOGY

A locally closed conformation of a bacterial pentameric proton-gated ion channel

(2012) Marie S Prevost et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Computer modeling of nitroxide spin labels on proteins

(2011) Ma'mon M. Hatmal et al.   BIOPOLYMERS

Structure of the M2 Transmembrane Segment of GLIC, a Prokaryotic Cys Loop Receptor Homologue fromGloeobacter violaceus, Probed by Substituted Cysteine Accessibility

(2011) Rishi B. Parikh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist

(2011) Shu-Xing Li et al.   NATURE NEUROSCIENCE

Electron Spin-Echo Envelope Modulation (ESEEM) Reveals Water and Phosphate Interactions with the KcsA Potassium Channel,

(2010) John A. Cieslak et al.   BIOCHEMISTRY

Increased Sensitivity and Extended Range of Distance Measurements in Spin-Labeled Membrane Proteins: Q-Band Double Electron-Electron Resonance and Nanoscale Bilayers

(2010) Ping Zou et al.   BIOPHYSICAL JOURNAL

Bridging the Gap between Structural Models of Nicotinic Receptor Superfamily Ion Channels and Their Corresponding Functional States

(2010) Giovanni Gonzalez-Gutierrez et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural basis for the coupling between activation and inactivation gates in K+ channels

(2010) Luis G. Cuello et al.   NATURE

3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels

(2010) John E. Baenziger et al.   NEUROPHARMACOLOGY

Binding, activation and modulation of Cys-loop receptors

(2010) Paul S. Miller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Significantly Improved Sensitivity of Q-Band PELDOR/DEER Experiments Relative to X-Band Is Observed in Measuring the Intercoil Distance of a Leucine Zipper Motif Peptide (GCN4-LZ)

(2009) Harishchandra Ghimire et al.   BIOCHEMISTRY

Conformational Changes in the Nicotinic Acetylcholine Receptor during Gating and Desensitization

(2009) Innocent H. Yamodo et al.   BIOCHEMISTRY

Structural Rearrangements in Loop F of the GABA Receptor Signal Ligand Binding, Not Channel Activation

(2009) Alpa Khatri et al.   BIOPHYSICAL JOURNAL

A prokaryotic perspective on pentameric ligand-gated ion channel structure

(2009) Ricarda JC Hilf et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain

(2009) Stephan A. Pless et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Lipid-dependent Uncoupled Conformation of the Acetylcholine Receptor

(2009) Corrie J. B. daCosta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anionic Lipids Allosterically Modulate Multiple Nicotinic Acetylcholine Receptor Conformational Equilibria

(2009) Corrie J. B. daCosta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biophysical and Ion Channel Functional Characterization of the Torpedo californica Nicotinic Acetylcholine Receptor in Varying Detergent–Lipid Environments

(2008) Guillermo A. Asmar-Rovira et al.   JOURNAL OF MEMBRANE BIOLOGY

Structural Mechanisms Underlying Benzodiazepine Modulation of the GABAA Receptor

(2008) S. M. Hanson et al.   JOURNAL OF NEUROSCIENCE

Agonist- and antagonist-induced conformational changes of loop F and their contributions to the ρ1 GABA receptor function

(2008) Jianliang Zhang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

(2008) C. Altenbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Structural Mechanism for MscS Gating in Lipid Bilayers

(2008) V. Vasquez et al.   SCIENCE