The Rho Exchange Factors Vav2 and Vav3 Favor Skin Tumor Initiation and Promotion by Engaging Extracellular Signaling Loops

Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival

(2012) K. H. Chang et al.   BLOOD

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma

(2012) Vladimir Ratushny et al.   JOURNAL OF CLINICAL INVESTIGATION

The Rho Exchange Factors Vav2 and Vav3 Control a Lung Metastasis-Specific Transcriptional Program in Breast Cancer Cells

(2012) C. Citterio et al.   Science Signaling

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

(2011) Colin R. Lindsay et al.   Nature Communications

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Transcriptional Factor Aryl Hydrocarbon Receptor (Ahr) Controls Cardiovascular and Respiratory Functions by Regulating the Expression of theVav3Proto-oncogene

(2010) Vincent Sauzeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P-Rex1 and Vav1 Cooperate in the Regulation of Formyl-Methionyl-Leucyl-Phenylalanine-Dependent Neutrophil Responses

(2010) C. D. Lawson et al.   JOURNAL OF IMMUNOLOGY

Vav3-deficient Mice Exhibit a Transient Delay in Cerebellar Development

(2010) Celia Quevedo et al.   MOLECULAR BIOLOGY OF THE CELL

Vav3 Is Involved in GABAergic Axon Guidance Events Important for the Proper Function of Brainstem Neurons Controlling Cardiovascular, Respiratory, and Renal Parameters

(2010) Vincent Sauzeau et al.   MOLECULAR BIOLOGY OF THE CELL

Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis

(2010) Okkyung Rho et al.   MOLECULAR CARCINOGENESIS

Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo

(2010) Z Wang et al.   ONCOGENE

Molecular Mechanisms of Mouse Skin Tumor Promotion

(2010) Joyce E. Rundhaug et al.   Cancers

The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in ApcMin/+mice

(2009) Yoshihiro Kawasaki et al.   EMBO REPORTS

The Rho/Rac exchange factor Vav2 controls nitric oxide–dependent responses in mouse vascular smooth muscle cells

(2009) Vincent Sauzeau et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic architecture of mouse skin inflammation and tumour susceptibility

(2009) David A. Quigley et al.   NATURE

Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications

(2009) Erika L Abel et al.   Nature Protocols

Function of the Nucleotide Exchange Activity of Vav1 in T Cell Development and Activation

(2009) A. Saveliev et al.   Science Signaling

Mechanistic Analysis of the Amplification and Diversification Events Induced by Vav Proteins in B-lymphocytes

(2008) María J. Caloca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE