Molecular basis for the recognition of cyclic-di-AMP by PstA, a PII-like signal transduction protein

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

(2015) TuAnh Ngoc Huynh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cyclic Dinucleotide c-di-AMP Is an Allosteric Regulator of Metabolic Enzyme Function

(2014) Kamakshi Sureka et al.   CELL

Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA

(2014) C. P. Jones et al.   EMBO JOURNAL

c-di-AMP recognition byStaphylococcus aureusPstA

(2014) Martina Müller et al.   FEBS LETTERS

Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding PII-like Signal Transduction Protein DarA

(2014) Jan Gundlach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex Structure and Biochemical Characterization of theStaphylococcus aureusCyclic Diadenylate Monophosphate (c-di-AMP)-binding Protein PstA, the Founding Member of a New Signal Transduction Protein Family

(2014) Ivan Campeotto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural insights into recognition of c-di-AMP by the ydaO riboswitch

(2014) Ang Gao et al.   Nature Chemical Biology

c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry–related pockets

(2014) Aiming Ren et al.   Nature Chemical Biology

Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic Di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence

(2013) Y. Bai et al.   JOURNAL OF BACTERIOLOGY

Cyclic Di-AMP Impairs Potassium Uptake Mediated by a Cyclic Di-AMP Binding Protein in Streptococcus pneumoniae

(2013) Y. Bai et al.   JOURNAL OF BACTERIOLOGY

Interaction of Apurinic/Apyrimidinic Endonucleases Nfo and ExoA with the DNA Integrity Scanning Protein DisA in the Processing of Oxidative DNA Damage during Bacillus subtilis Spore Outgrowth

(2013) S. S. Campos et al.   JOURNAL OF BACTERIOLOGY

Riboswitches in eubacteria sense the second messenger c-di-AMP

(2013) James W Nelson et al.   Nature Chemical Biology

Cyclic di-AMP: another second messenger enters the fray

(2013) Rebecca M. Corrigan et al.   NATURE REVIEWS MICROBIOLOGY

Systematic identification of conserved bacterial c-di-AMP receptor proteins

(2013) R. M. Corrigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclic di-AMP Is Critical for Listeria monocytogenes Growth, Cell Wall Homeostasis, and Establishment of Infection

(2013) C. E. Witte et al.   mBio

Heat Resistance and Salt Hypersensitivity in Lactococcus lactis Due to Spontaneous Mutation ofllmg_1816(gdpP) Induced by High-Temperature Growth

(2012) William M. Smith et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cyclic Di-AMP Homeostasis inBacillus subtilis

(2012) Felix M. P. Mehne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DarR, a TetR-like Transcriptional Factor, Is a Cyclic Di-AMP-responsive Repressor inMycobacterium smegmatis

(2012) Lei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STING and the innate immune response to nucleic acids in the cytosol

(2012) Dara L Burdette et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis Rv3586 (DacA) Is a Diadenylate Cyclase That Converts ATP or ADP into c-di-AMP

(2012) Yinlan Bai et al.   PLoS One

Methicillin Resistance Alters the Biofilm Phenotype and Attenuates Virulence in Staphylococcus aureus Device-Associated Infections

(2012) Clarissa Pozzi et al.   PLoS Pathogens

c-di-AMP reports DNA integrity during sporulation in Bacillus subtilis

(2011) Yaara Oppenheimer-Shaanan et al.   EMBO REPORTS

Analysis of the role of Bacillus subtilis σM in β-lactam resistance reveals an essential role for c-di-AMP in peptidoglycan homeostasis

(2011) Yun Luo et al.   MOLECULAR MICROBIOLOGY

Crystal structure of the GlnZ-DraG complex reveals a different form of PII-target interaction

(2011) C. Rajendran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress

(2011) Rebecca M. Corrigan et al.   PLoS Pathogens

Listeria monocytogenes Triggers AIM2-Mediated Pyroptosis upon Infrequent Bacteriolysis in the Macrophage Cytosol

(2010) John-Demian Sauer et al.   Cell Host & Microbe

Structural basis for the regulation of NtcA-dependent transcription by proteins PipX and PII

(2010) J. L. Llacer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein

(2010) Nishant D. Shetty et al.   PROTEIN SCIENCE

c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

(2010) J. J. Woodward et al.   SCIENCE

YybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity

(2009) Feng Rao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates

(2008) Gregor Witte et al.   MOLECULAR CELL