Abnormalities in the zinc-metalloprotease-BDNF axis may contribute to megalencephaly and cortical hyperconnectivity in young autism spectrum disorder patients

Increased BDNF expression in fetal brain in the valproic acid model of autism

(2014) Luis E.F. Almeida et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The role of de novo mutations in the genetics of autism spectrum disorders

(2014) Michael Ronemus et al.   NATURE REVIEWS GENETICS

Enhancement of Inhibitory Neurotransmission by GABA A Receptors Having α 2,3 -Subunits Ameliorates Behavioral Deficits in a Mouse Model of Autism

(2014) Sung Han et al.   NEURON

Transcriptomic Analyses of Neurotoxic Effects in Mouse Brain After Intermittent Neonatal Administration of Thimerosal

(2014) Xiaoling Li et al.   TOXICOLOGICAL SCIENCES

Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders

(2013) Stefanie Grabrucker et al.   BRAIN

A role for synaptic zinc in ProSAP/Shank PSD scaffold malformation in autism spectrum disorders

(2013) Andreas M. Grabrucker   Developmental Neurobiology

Calpain-2-Mediated PTEN Degradation Contributes to BDNF-Induced Stimulation of Dendritic Protein Synthesis

(2013) V. Briz et al.   JOURNAL OF NEUROSCIENCE

The Fragile X Mental Retardation Protein Regulates Matrix Metalloproteinase 9 mRNA at Synapses

(2013) A. Janusz et al.   JOURNAL OF NEUROSCIENCE

Brain-Derived Neurotrophic Factor Induces Matrix Metalloproteinase 9 Expression in Neurons via the Serum Response Factor/c-Fos Pathway

(2013) B. Kuzniewska et al.   MOLECULAR AND CELLULAR BIOLOGY

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Christianson Syndrome Protein NHE6 Modulates TrkB Endosomal Signaling Required for Neuronal Circuit Development

(2013) Qing Ouyang et al.   NEURON

Effect of thimerosal on the neurodevelopment of premature rats

(2013) Yan-Ni Chen et al.   World Journal of Pediatrics

Local Functional Overconnectivity in Posterior Brain Regions Is Associated with Symptom Severity in Autism Spectrum Disorders

(2013) Christopher Lee Keown et al.   Cell Reports

Brain Hyperconnectivity in Children with Autism and its Links to Social Deficits

(2013) Kaustubh Supekar et al.   Cell Reports

SHANK3 haploinsufficiency: a “common” but underdiagnosed highly penetrant monogenic cause of autism spectrum disorders

(2013) Catalina Betancur et al.   Molecular Autism

Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action

(2013) Thomas A Lanz et al.   Molecular Autism

A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States

(2013) David A Geier et al.   Translational Neurodegeneration

Levels of Heavy Metals and Essential Minerals in Hair Samples of Children with Autism in Oman: a Case–Control Study

(2012) Yahya M. Al-Farsi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Electroconvulsive seizure, but not imipramine, rapidly up-regulates pro-BDNF and t-PA, leading to mature BDNF production, in the rat hippocampus

(2012) Masahiro Segawa et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Expressions of Brain-Derived Neurotrophic Factor (BDNF) in Cerebrospinal Fluid and Plasma of Children With Meningitis and Encephalitis/Encephalopathy

(2012) Shinichiro Morichi et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Neonatal levels of cytokines and risk of autism spectrum disorders: An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank

(2012) Morsi W. Abdallah et al.   JOURNAL OF NEUROIMMUNOLOGY

Members of the Myocyte Enhancer Factor 2 Transcription Factor Family Differentially Regulate Bdnf Transcription in Response to Neuronal Depolarization

(2012) M. R. Lyons et al.   JOURNAL OF NEUROSCIENCE

Trajectories of Early Brain Volume Development in Fragile X Syndrome and Autism

(2012) Heather Cody Hazlett et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

Matrix Metalloproteinases and Minocycline: Therapeutic Avenues for Fragile X Syndrome

(2012) Saul S. Siller et al.   NEURAL PLASTICITY

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

(2011) Joachim Hallmayer   ARCHIVES OF GENERAL PSYCHIATRY

Aberrant Striatal Functional Connectivity in Children with Autism

(2011) Adriana Di Martino et al.   BIOLOGICAL PSYCHIATRY

Underconnected, but How? A Survey of Functional Connectivity MRI Studies in Autism Spectrum Disorders

(2011) Ralph-Axel Müller et al.   CEREBRAL CORTEX

Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase

(2011) S. S. Siller et al.   Disease Models & Mechanisms

Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

(2011) Andreas M Grabrucker et al.   EMBO JOURNAL

Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region

(2011) Ramón A. Lorca et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuron Number and Size in Prefrontal Cortex of Children With Autism

(2011) Eric Courchesne et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Circuit-Specific Intracortical Hyperconnectivity in Mice with Deletion of the Autism-Associated Met Receptor Tyrosine Kinase

(2011) S. Qiu et al.   JOURNAL OF NEUROSCIENCE

Matrix Metalloproteinase-9 Contributes to Kindled Seizure Development in Pentylenetetrazole-Treated Mice by Converting Pro-BDNF to Mature BDNF in the Hippocampus

(2011) H. Mizoguchi et al.   JOURNAL OF NEUROSCIENCE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Increased Secreted Amyloid Precursor Protein-α (sAPPα) in Severe Autism: Proposal of a Specific, Anabolic Pathway and Putative Biomarker

(2011) Balmiki Ray et al.   PLoS One

The Intense World Theory – A Unifying Theory of the Neurobiology of Autism

(2010) Kamila Markram et al.   Frontiers in Human Neuroscience

BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse

(2010) Verna Louhivuori et al.   NEUROBIOLOGY OF DISEASE

Prenatal and Infant Exposure to Thimerosal From Vaccines and Immunoglobulins and Risk of Autism

(2010) C. S. Price et al.   PEDIATRICS

Autism and other neuropsychiatric symptoms are prevalent in individuals withMeCP2duplication syndrome

(2009) Melissa B. Ramocki et al.   ANNALS OF NEUROLOGY

Evidence for a release of brain-derived neurotrophic factor from the brain during exercise

(2009) Peter Rasmussen et al.   EXPERIMENTAL PHYSIOLOGY

New Insights in the Biology of BDNF Synthesis and Release: Implications in CNS Function

(2009) M. E. Greenberg et al.   JOURNAL OF NEUROSCIENCE

Whither proBDNF?

(2009) Philip A Barker   NATURE NEUROSCIENCE

Zinc-Mediated Transactivation of TrkB Potentiates the Hippocampal Mossy Fiber-CA3 Pyramid Synapse

(2009) Yang Z. Huang et al.   NEURON

Big heads, small details and autism

(2009) Sarah White et al.   NEUROPSYCHOLOGIA

Radial cytoarchitecture and patterns of cortical connectivity in autism

(2009) M. Casanova et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

SLC9A6 Mutations Cause X-Linked Mental Retardation, Microcephaly, Epilepsy, and Ataxia, a Phenotype Mimicking Angelman Syndrome

(2008) Gregor D. Gilfillan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Autism: Many Genes, Common Pathways?

(2008) Daniel H. Geschwind   CELL

Testosterone-Induced Matrix Metalloproteinase Activation Is a Checkpoint for Neuronal Addition to the Adult Songbird Brain

(2008) D.-H. Kim et al.   JOURNAL OF NEUROSCIENCE

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF

(2008) Tomoya Matsumoto et al.   NATURE NEUROSCIENCE

Proteolysis of proBDNF Is a Key Regulator in the Formation of Memory

(2008) Philip Barnes et al.   PLoS One

Brainstem volumetric alterations in children with autism

(2008) R. J. Jou et al.   PSYCHOLOGICAL MEDICINE

Neuroanatomy of autism

(2008) David G. Amaral et al.   TRENDS IN NEUROSCIENCES

ADAM-10 over-expression increases cortical synaptogenesis

(2006) Karen F.S. Bell et al.   NEUROBIOLOGY OF AGING