Liraglutide protects pancreatic beta cells during an early intervention in Gato-Kakizaki rats (Gato-Kakizaki大鼠使用利拉鲁肽进行早期干预可以保护胰腺β细胞)

Early intervention with liraglutide improves glucose tolerance without affecting islet microcirculation in young Goto–Kakizaki rats

(2012) Lin Wu et al.   REGULATORY PEPTIDES

Pancreatic islet-specific overexpression of Reg3β protein induced the expression of pro-islet genes and protected the mice against streptozotocin-induced diabetes mellitus

(2011) Xiaoquan Xiong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

IL-1β Activation as a Response to Metabolic Disturbances

(2010) Marc Y. Donath et al.   Cell Metabolism

Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets

(2010) K. W. Sloop et al.   DIABETES

Anti-inflammatory action of exendin-4 in human islets is enhanced by phosphodiesterase inhibitors: potential therapeutic benefits in diabetic patients

(2010) U. Pugazhenthi et al.   DIABETOLOGIA

Targeting β-Cell Function Early in the Course of Therapy for Type 2 Diabetes Mellitus

(2010) Jack L. Leahy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

(2010) Seth L Masters et al.   NATURE IMMUNOLOGY

Fate of the beta-cell in the pathophysiology of type 2 diabetes

(2009) R. Keith Campbell   JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat

(2009) J. A. Ehses et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-proliferative effect of pro-inflammatory cytokines in cultured β cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of glucagon-like peptide -1

(2008) M Blandino-Rosano et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The GK rat beta-cell: A prototype for the diseased human beta-cell in type 2 diabetes?

(2008) B. Portha et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Facilitating effects of berberine on rat pancreatic islets through modulating hepatic nuclear factor 4 alpha expression and glucokinase activity

(2008) Zhi-Quan Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY