Recognition of Immune Response for the Early Diagnosis and Treatment of Osteoarthritis

A formyl peptide receptor agonist suppresses inflammation and bone damage in arthritis

(2014) W Kao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Leptin induces ADAMTS-4, ADAMTS-5, and ADAMTS-9 genes expression by mitogen-activated protein kinases and NF-ĸB signaling pathways in human chondrocytes

(2014) Kursat Oguz Yaykasli et al.   CELL BIOLOGY INTERNATIONAL

A fluorescent light-up probe as an inhibitor of intracellular β-tryptase

(2014) Qi Wang et al.   CHEMICAL COMMUNICATIONS

In Vivo Tracking of Th1 Cells by PET Reveals Quantitative and Temporal Distribution and Specific Homing in Lymphatic Tissue

(2014) C. M. Griessinger et al.   JOURNAL OF NUCLEAR MEDICINE

Pathogenesis and Prevention of Posttraumatic Osteoarthritis After Intra-articular Fracture

(2014) Mara L. Schenker et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development

(2014) G Girardi et al.   MOLECULAR PSYCHIATRY

Association between adiponectin and cartilage degradation in human osteoarthritis

(2014) P.-J. Francin et al.   OSTEOARTHRITIS AND CARTILAGE

Significance of Preradiographic Magnetic Resonance Imaging Lesions in Persons at Increased Risk of Knee Osteoarthritis

(2014) Leena Sharma et al.   Arthritis & Rheumatology

New horizons in osteoarthritis

(2013) C. Y. J. Wenham et al.   AGE AND AGEING

Immunopathogenesis of osteoarthritis

(2013) Abdul Haseeb et al.   CLINICAL IMMUNOLOGY

Osteoarthritis year in review 2013: biology

(2013) R.F. Loeser   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis year 2013 in review: biomarkers; reflecting before moving forward, one step at a time

(2013) F.P.J.G. Lafeber et al.   OSTEOARTHRITIS AND CARTILAGE

Proteoglycan 4 Expression Protects Against the Development of Osteoarthritis

(2013) M. Z. C. Ruan et al.   Science Translational Medicine

PET Imaging of Inflammation Biomarkers

(2013) Chenxi Wu et al.   Theranostics

Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations

(2013) Jeremy Sokolove et al.   Therapeutic Advances in Musculoskeletal Disease

The Impact of Osteoarthritis in the United States

(2012) Louise Murphy et al.   AMERICAN JOURNAL OF NURSING

Gd3+cFLFLFK conjugate for MRI: a targeted contrast agent for FPR1 in inflammation

(2012) Graeme J. Stasiuk et al.   CHEMICAL COMMUNICATIONS

Prognostic biomarkers in osteoarthritis

(2012) Mukundan Attur et al.   CURRENT OPINION IN RHEUMATOLOGY

Use of imaging techniques to predict progression in osteoarthritis

(2012) Changhai Ding et al.   CURRENT OPINION IN RHEUMATOLOGY

Osteoarthritis, inflammation and obesity

(2012) Francis Berenbaum et al.   CURRENT OPINION IN RHEUMATOLOGY

A practical MRI grading system for osteoarthritis of the knee: Association with Kellgren–Lawrence radiographic scores

(2012) Hee-Jin Park et al.   EUROPEAN JOURNAL OF RADIOLOGY

Real-time detection of implant-associated neutrophil responses using a formyl peptide receptor-targeting NIR nanoprobe

(2012) Jun Zhou et al.   International Journal of Nanomedicine

Clinical relevance of bone marrow lesions in OA

(2012) C. Kent Kwoh   Nature Reviews Rheumatology

Recent advances in osteoarthritis imaging—the Osteoarthritis Initiative

(2012) Felix Eckstein et al.   Nature Reviews Rheumatology

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

(2012) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

Imaging inflammation: Molecular strategies to visualize key components of the inflammatory cascade, from initiation to resolution

(2012) D.A. Dorward et al.   PHARMACOLOGY & THERAPEUTICS

Evaluation of Dynamic [18F]-FDG-PET Imaging for the Detection of Acute Post-Surgical Bone Infection

(2012) Tracy L. Y. Brown et al.   PLoS One

Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4

(2012) Dong Sohn et al.   ARTHRITIS RESEARCH & THERAPY

Presence of MRI-detected joint effusion and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30-month follow-up: the MOST study

(2011) F. W. Roemer et al.   ANNALS OF THE RHEUMATIC DISEASES

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

(2011) Wang Hui et al.   ANNALS OF THE RHEUMATIC DISEASES

Risk factors for magnetic resonance imaging-detected patellofemoral and tibiofemoral cartilage loss during a six-month period: The Joints On Glucosamine study

(2011) Frank W. Roemer et al.   ARTHRITIS AND RHEUMATISM

Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4

(2011) Rik F. P. Schelbergen et al.   ARTHRITIS AND RHEUMATISM

Diagnosis of osteoarthritis: Imaging

(2011) Hillary J. Braun et al.   BONE

Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice

(2011) Stephanos Kyrkanides et al.   Journal of Neuroinflammation

Identification of a central role for complement in osteoarthritis

(2011) Qian Wang et al.   NATURE MEDICINE

Molecular targets of natural health products in arthritis

(2011) Sarah Khalifé et al.   ARTHRITIS RESEARCH & THERAPY

Why radiography should no longer be considered a surrogate outcome measure for longitudinal assessment of cartilage in knee osteoarthritis

(2011) Ali Guermazi et al.   ARTHRITIS RESEARCH & THERAPY

Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy

(2011) Xavier Chevalier et al.   ARTHRITIS RESEARCH & THERAPY

Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes

(2011) Nahid Akhtar et al.   ARTHRITIS RESEARCH & THERAPY

Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium

(2011) Jolien Suurmond et al.   ARTHRITIS RESEARCH & THERAPY

In vivo bioluminescence imaging of Burkholderia mallei respiratory infection and treatment in the mouse model

(2011) Shane Massey   Frontiers in Microbiology

Synovial tissue-infiltrating natural killer cells in osteoarthritis and periprosthetic inflammation

(2010) Ryan S. Huss et al.   ARTHRITIS AND RHEUMATISM

The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis

(2010) Jan Bondeson et al.   ARTHRITIS AND RHEUMATISM

Neutrophil Targeting Heterobivalent SPECT Imaging Probe: cFLFLF-PEG-TKPPR-99mTc

(2010) Yi Zhang et al.   BIOCONJUGATE CHEMISTRY

Synthesis of the Cyanine 7 labeled neutrophil-specific agents for noninvasive near infrared fluorescence imaging

(2010) Li Xiao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Osteoarthritis: can anti-cytokine therapy play a role in treatment?

(2010) Ana Luisa G. Calich et al.   CLINICAL RHEUMATOLOGY

Editorial [Hot Topic: Waiting for Action on the Osteoarthritis Front (Guest Editors: Virginia Byers Kraus and Thomas Aigner)]

(2010) Virginia Kraus   CURRENT DRUG TARGETS

Anticytokine Therapy for Osteoarthritis

(2010) Charles J. Malemud   DRUGS & AGING

The infrapatellar fat pad should be considered as an active osteoarthritic joint tissue: a narrative review

(2010) S. Clockaerts et al.   OSTEOARTHRITIS AND CARTILAGE

Bone marrow lesions in people with knee osteoarthritis predict progression of disease and joint replacement: a longitudinal study

(2010) S. K. Tanamas et al.   RHEUMATOLOGY

Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

(2010) Birgit Riepl et al.   ARTHRITIS RESEARCH & THERAPY

Cartilage proteoglycan aggrecan epitopes induce proinflammatory autoreactive T-cell responses in rheumatoid arthritis and osteoarthritis

(2009) H de Jong et al.   ANNALS OF THE RHEUMATIC DISEASES

Prostaglandin E2and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis

(2009) Xin Li et al.   ARTHRITIS AND RHEUMATISM

N-Acetylcysteine Inhibits Post-Impact Chondrocyte Death in Osteochondral Explants

(2009) James A Martin et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

A Novel Neutrophil-Specific PET Imaging Agent: cFLFLFK-PEG-64Cu

(2009) L. W. Locke et al.   JOURNAL OF NUCLEAR MEDICINE

Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease

(2009) C.R. Scanzello et al.   OSTEOARTHRITIS AND CARTILAGE

A histomorphometric analysis of synovial biopsies from individuals with Gulf War Veterans’ Illness and joint pain compared to normal and osteoarthritis synovium

(2008) F. Pessler et al.   CLINICAL RHEUMATOLOGY

Neutrophil primary granule proteins HBP and HNP1–3 boost bacterial phagocytosis by human and murine macrophages

(2008) Oliver Soehnlein et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-1β and interleukin-6 disturb the antioxidant enzyme system in bovine chondrocytes: a possible explanation for oxidative stress generation

(2008) M. Mathy-Hartert et al.   OSTEOARTHRITIS AND CARTILAGE

Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid

(2008) W.H. Busby et al.   OSTEOARTHRITIS AND CARTILAGE