Review
Nutrition & Dietetics
Sunil K. Panchal, Oliver D. John, Michael L. Mathai, Lindsay Brown
Summary: Anthocyanins are purple-coloured phenolic compounds of plant origin with health benefits in humans by improving gut microbiota, reducing oxidative stress and inflammation, and modulating insulin-like growth factor-1. Their health benefits in humans include reducing cognitive decline, protecting organs, improving bone health and obesity, and regulating glucose and lipid metabolism.
Article
Food Science & Technology
Xiaoqiang Chen, Zihan Li, Shihan Yang, Ying Zhang
Summary: Natural anthocyanins from Rubia sylvatica fruit have been found to have a protective effect against oxidative stress in retinal pigment epithelial cells. They reduce oxidation products, increase antioxidant enzyme activity, enhance cell viability, and decrease apoptosis. The mechanism involves the activation of protein kinase B (Akt) through its phosphorylation process.
Article
Environmental Sciences
Maria Karolina Martins Ferreira, Walessa Alana Braganca Araga, Leonardo Oliveira Bittencourt, Bruna Puty, Aline Dionizio, Michel Platini Caldas de Souza, Marilia Afonso Rabelo Buzalaf, Edivaldo Herculano de Oliveira, Maria Elena Crespo-Lopez, Rafael Rodrigues Lima
Summary: This study found that exposure to two concentrations of fluoride during pregnancy and lactation can increase fluoride bioavailability, trigger redox imbalance characterized by decreased ACAP, increased LPO and NO2- levels, BDNF overexpression, and changes in the hippocampal proteome.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Food Science & Technology
Yingjun Hu, Zipeng Yan, Yang He, Yan Li, Meng Li, Yuanyuan Li, DingLi Zhang, Yangfei Zhao, Mohammad Mehdi Ommati, Jundong Wang, Meijun Huo, Jinming Wang
Summary: Excessive fluoride exposure can lead to oxidative stress in the kidney. Selenium, as an antioxidant, can potentially protect the kidney from fluoride-induced injury in rats. The supplementation of 1-2 mg/L selenium effectively ameliorated fluoride-induced renal injury through oxidative stress and apoptosis-related pathways, possibly through the activation of the Nrf2/HO-1/NQO1 signaling pathway.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Albino Carrizzo, Rosario Lizio, Paola Di Pietro, Michele Ciccarelli, Antonio Damato, Eleonora Venturini, Patrizia Iannece, Eduardo Sommella, Pietro Campiglia, Philipp Ockermann, Carmine Vecchione
Summary: The research demonstrated that Healthberry 865(R) has a significant vasodilatory effect on resistance artery function in mice, mediated by nitric oxide release through the PI3K/Akt signaling pathway. It also exerts an antioxidant effect by modulating NADPH oxidase. The selective action of different anthocyanins mediates the cardiovascular properties of Healthberry 865(R), reducing oxidative stress and improving nitric oxide bioavailability.
Review
Biochemistry & Molecular Biology
Aleksandra Kozlowska, Tomasz Dzierzanowski
Summary: Anthocyanins play a promising role in regulating inflammation and activating antioxidant defenses. Clinical studies have shown that anthocyanins supplementation can regulate inflammatory markers in both healthy individuals and those with chronic diseases. However, long-term clinical trials are needed to quantify the progression of inflammation effectively.
Article
Environmental Sciences
Jelena Radovanovic, Biljana Antonijevic, Marijana Curcic, Katarina Baralic, Stoimir Kolarevic, Zorica Bulat, Danijela Dukic-cosic, Aleksandra Buha Djordjevic, Branka Vukovic-Gacic, Dragana Javorac, Evica Antonijevic Miljakovic, Momir Carevic, Zoran Mandinic
Summary: Excessive fluoride exposure can lead to pathological changes in testicular tissues, affecting oxidative stress, essential elements levels, and DNA damage. SOD1 activity and DNA damage are the most sensitive indicators, with the lowest BMDLs at 0.1 µg F-/kg b.w. This study provides valuable insights for further research on the health risks associated with fluoride exposure in both human and animal populations.
ENVIRONMENTAL POLLUTION
(2022)
Article
Agronomy
Taeko Koji, Hiroyoshi Iwata, Motoyuki Ishimori, Hideki Takanashi, Yuji Yamasaki, Hisashi Tsujimoto
Summary: The change in appearance during the seasonal transitions in ornamental greening plants is an important characteristic. In this study, we established a method for phenotyping leaf color change by multispectral imaging and performed genetic analysis to explore the potential of this approach in breeding greening plants. The results suggest the potential of multispectral phenotyping in the genetic dissection of seasonal leaf color changes in greening plants.
Review
Biochemistry & Molecular Biology
Kim S. Stote, Gracie Burns, Kim Mears, Marva Sweeney, Cynthia Blanton
Summary: Bioactive compounds in berries protect DNA, proteins, and lipids from oxidative damage by scavenging reactive oxygen and nitrogen species. This study reviewed randomized controlled trials (RCTs) to examine the effects of non-acute berry consumption on biomarkers of oxidative stress. Out of the 28 RCTs evaluated, 32% of the biomarkers showed statistically significant beneficial results, while 68% showed no significant differences. Further well-designed and longer-term trials are needed to assess biomarkers of oxidative stress.
Article
Food Science & Technology
Rui Li, Zhan Ye, Yong-jiang Xu, Yuanfa Liu
Summary: This study investigates the protective role of blueberry anthocyanin extracts (BAEs), particularly its anti-oxidant constituent, cyanidin-3-O-glucoside (C3G), against damage to retinal pigment epithelium (RPE) cells induced by high glucose (HG) levels. The findings suggest that BAEs mitigated damage to HG-induced RPE cells by decreasing intracellular reactive oxygen species (ROS) levels and improving cell morphology and viability. The underlying mechanism involves C3G interrupting ROS generation feedback loop, downregulating REDD1 expression, enhancing retinal Nrf2 antioxidant response, and suppressing VEGFA expression to prevent an increase in vascular permeability.
Article
Biochemistry & Molecular Biology
Haojie Li, Zijun Hao, Li Wang, Jiarong Yang, Yangfei Zhao, Xiaofang Cheng, Haiyan Yuan, Jinming Wang
Summary: Excessive fluoride exposure induced liver damage and oxidative stress, activating mitochondrial-mediated apoptosis. However, supplementation of 1% calcium carbonate alleviated fluoride-induced liver cell damage through inhibiting the mitochondrial apoptosis pathway.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Orawan Wongmekiat, Narissara Lailerd, Anongporn Kobroob, Wachirasek Peerapanyasut
Summary: The study demonstrated that purple rice husk extract has a protective effect against diabetic kidney injury by improving mitochondrial function and reducing oxidative damage. This finding opens up possibilities for developing agricultural waste into useful products for diabetes health.
Article
Agronomy
Taeko Koji, Hiroyoshi Iwata, Motoyuki Ishimori, Hideki Takanashi, Yuji Yamasaki, Hisashi Tsujimoto
Summary: This study established a method for phenotyping leaf color change using multispectral imaging and genetic analysis, demonstrating the potential of this approach in breeding greening plants. The results showed that multispectral phenotyping captured genetic variation in leaf color and could be used for genetic dissection of seasonal leaf color changes in greening plants.
Article
Nutrition & Dietetics
Soo Im Chung, Su Noh Ryu, Mi Young Kang
Summary: The study found that adding extracts from dark purple Superjami rice bran can alleviate bone loss and oxidative stress in menopause-induced animal models, helping to prevent postmenopausal osteoporosis and oxidative damage.
Article
Food Science & Technology
Kwanele A. Nxumalo, Olaniyi A. Fawole
Summary: This study found that applying chitosan edible coating enriched with herbal plant extracts can effectively alleviate shrivel and maintain the quality of purple passion fruit. Fruit coated with Ch+B performed the best and showed potential for commercial applications.
FOOD QUALITY AND SAFETY
(2022)
