Biodegradable particles as vaccine antigen delivery systems for stimulating cellular immune responses

The Combination of a Low-Dose Chemotherapeutic Agent, 5-Fluorouracil, and an Adenoviral Tumor Vaccine Has a Synergistic Benefit on Survival in a Tumor Model System

(2013) Sean M. Geary et al.   PLoS One

Evaluation of mucoadhesive carrier adjuvant: Toward an oral anthrax vaccine

(2013) Sharad Mangal et al.   Artificial Cells Nanomedicine and Biotechnology

Biodegradable Particles as Vaccine Delivery Systems: Size Matters

(2012) Vijaya B. Joshi et al.   AAPS Journal

Characterizing the antitumor response in mice treated with antigen-loaded polyanhydride microparticles

(2012) Vijaya B. Joshi et al.   Acta Biomaterialia

Synthesis of TAT peptide-tagged PEGylated chitosan nanoparticles for siRNA delivery targeting neurodegenerative diseases

(2012) Meenakshi Malhotra et al.   BIOMATERIALS

The effect of antigen encapsulation in chitosan particles on uptake, activation and presentation by antigen presenting cells

(2012) Bhanuprasanth Koppolu et al.   BIOMATERIALS

Chitosan-based delivery systems for mucosal vaccines

(2012) Inderjit Jabbal-Gill et al.   Expert Opinion on Drug Delivery

Development of an siRNA delivery system targeting macrophage function in-vivo

(2012) Felix C. Blanco et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

(2012) Steffen Walter et al.   NATURE MEDICINE

Antigen-Displaying Lipid-Enveloped PLGA Nanoparticles as Delivery Agents for a Plasmodium vivax Malaria Vaccine

(2012) James J. Moon et al.   PLoS One

A simple approach for enhanced immune response using engineered dendritic cell targeted nanoparticles

(2012) Dharmendra Raghuwanshi et al.   VACCINE

Intranasal immunisation of mice against Streptococcus equi using positively charged nanoparticulate carrier systems

(2012) L. Figueiredo et al.   VACCINE

Evaluation of Biocompatibility and Administration Site Reactogenicity of Polyanhydride-Particle-Based Platform for Vaccine Delivery

(2012) Lucas Huntimer et al.   Advanced Healthcare Materials

A New Strategy Based on Smrho Protein Loaded Chitosan Nanoparticles as a Candidate Oral Vaccine against Schistosomiasis

(2012) Carolina R. Oliveira et al.   PLoS Neglected Tropical Diseases

Efficacy of polymeric encapsulated C5a peptidase–based group B streptococcus vaccines in a murine model

(2011) Donna A. Santillan et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Activation of innate immune responses in a pathogen-mimicking manner by amphiphilic polyanhydride nanoparticle adjuvants

(2011) Latrisha K. Petersen et al.   BIOMATERIALS

Immunostimulatory sutures that treat local disease recurrence following primary tumor resection

(2011) Janjira Intra et al.   Biomedical Materials

Tumor immunotherapy using adenovirus vaccines in combination with intratumoral doses of CpG ODN

(2011) S. M. Geary et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Formation mechanism of monodisperse, low molecular weight chitosan nanoparticles by ionic gelation technique

(2011) Wen Fan et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Surface Engineered Nanoparticles for Oral Immunization

(2011) Basant Malik et al.   Journal of Biomedical Nanotechnology

Chitosan Is a Surprising Negative Modulator of Cytotoxic CD8+T Cell Responses Elicited by Adenovirus Cancer Vaccines

(2011) Caitlin D. Lemke et al.   MOLECULAR PHARMACEUTICS

Norovirus Vaccine against Experimental Human Norwalk Virus Illness

(2011) Robert L. Atmar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Design of a Protective Single-Dose Intranasal Nanoparticle-Based Vaccine Platform for Respiratory Infectious Diseases

(2011) Bret D. Ulery et al.   PLoS One

PLGA, PLGA-TMC and TMC-TPP Nanoparticles Differentially Modulate the Outcome of Nasal Vaccination by Inducing Tolerance or Enhancing Humoral Immunity

(2011) Chantal Keijzer et al.   PLoS One

Effects of Glucocorticoid Receptor Small Interfering RNA Delivered Using Poly Lactic-Co-Glycolic Acid Microparticles on Proliferation and Differentiation Capabilities of Human Mesenchymal Stromal Cells

(2011) Liu Hong et al.   TISSUE ENGINEERING PART A

Rational Design of Pathogen-Mimicking Amphiphilic Materials as Nanoadjuvants

(2011) Bret D. Ulery et al.   Scientific Reports

Encapsulation into amphiphilic polyanhydride microparticles stabilizes Yersinia pestis antigens

(2010) Brenda Carrillo-Conde et al.   Acta Biomaterialia

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

Poly(Anhydride) Nanoparticles Act as Active Th1 Adjuvants through Toll-Like Receptor Exploitation

(2010) I. Tamayo et al.   Clinical and Vaccine Immunology

Polymeric particles in vaccine delivery

(2010) Allison C Rice-Ficht et al.   CURRENT OPINION IN MICROBIOLOGY

Use of defined TLR ligands as adjuvants within human vaccines

(2010) Malcolm S. Duthie et al.   IMMUNOLOGICAL REVIEWS

Rational design, fabrication, characterization andin vitrotesting of biodegradable microparticles that generate targeted and sustained transgene expression in HepG2 liver cells

(2010) Janjira Intra et al.   JOURNAL OF DRUG TARGETING

Preparation of N-Trimethyl Chitosan-Protein Nanoparticles Intended for Vaccine Delivery

(2010) Xing Yi Li et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Nanoparticle Delivery Systems in Cancer Vaccines

(2010) Yogita Krishnamachari et al.   PHARMACEUTICAL RESEARCH

Intracellular Release of 17-β Estradiol from Cationic Polyamidoamine Dendrimer Surface-Modified Poly (Lactic-co-Glycolic Acid) Microparticles Improves Osteogenic Differentiation of Human Mesenchymal Stromal Cells

(2010) Liu Hong et al.   TISSUE ENGINEERING PART C-METHODS

Principles of vaccine design—Lessons from nature

(2010) Fred Zepp   VACCINE

Innovative strategies for co-delivering antigens and CpG oligonucleotides

(2009) Yogita Krishnamachari et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeting the allergen to oral dendritic cells with mucoadhesive chitosan particles enhances tolerance induction

(2009) N. Saint-Lu et al.   ALLERGY

Effect of polymer chemistry and fabrication method on protein release and stability from polyanhydride microspheres

(2009) Senja K. Lopac et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Evaluation of properties of chitosan as an adjuvant for inactivated influenza vaccines administered parenterally

(2009) Yuri Ghendon et al.   JOURNAL OF MEDICAL VIROLOGY

Fabrication, characterization and in vitro evaluation of poly(D,L-lactide-co-glycolide) microparticles loaded with polyamidoamine–plasmid DNA dendriplexes for applications in nonviral gene delivery

(2009) Janjira Intra et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Physicochemical and Immunological Characterization of N,N,N-Trimethyl Chitosan-Coated Whole Inactivated Influenza Virus Vaccine for Intranasal Administration

(2009) Niels Hagenaars et al.   PHARMACEUTICAL RESEARCH

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy

(2009) Stacey L. Demento et al.   VACCINE

Immune stimulatory antigen loaded particles combined with depletion of regulatory T-cells induce potent tumor specific immunity in a mouse model of melanoma

(2008) Robin Goforth et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immunomodulatory biomaterials

(2008) Surya K. Mallapragada et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comparative study of poly (lactic-co-glycolic acid)-poly ethyleneimine-plasmid DNA microparticles prepared using double emulsion methods

(2008) Xue-Qing Zhang et al.   JOURNAL OF MICROENCAPSULATION

Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity

(2008) Samar Hamdy et al.   VACCINE

Formulating Poly(Lactide-Co-Glycolide) Particles for Plasmid DNA Delivery

(2007) Aiman O. Abbas et al.   JOURNAL OF PHARMACEUTICAL SCIENCES