A genome scale overexpression screen to reveal drug activity in human cells

A Functional Variomics Tool for Discovering Drug-Resistance Genes and Drug Targets

(2013) Zhiwei Huang et al.   Cell Reports

Generation of a Genome Scale Lentiviral Vector Library for EF1α Promoter-Driven Expression of Human ORFs and Identification of Human Genes Affecting Viral Titer

(2012) Dubravka Škalamera et al.   PLoS One

Yeast one-hybrid assays for gene-centered human gene regulatory network mapping

(2011) John S Reece-Hoyes et al.   NATURE METHODS

A public genome-scale lentiviral expression library of human ORFs

(2011) Xiaoping Yang et al.   NATURE METHODS

Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

A High-Throughput Platform for Lentiviral Overexpression Screening of the Human ORFeome

(2011) Dubravka Škalamera et al.   PLoS One

Protein Homeostasis and the Phenotypic Manifestation of Genetic Diversity: Principles and Mechanisms

(2010) Daniel F. Jarosz et al.   Annual Review of Genetics

Drug resistance in metastatic castration-resistant prostate cancer

(2010) Bostjan Seruga et al.   Nature Reviews Clinical Oncology

The Rhox genes

(2010) James A MacLean et al.   REPRODUCTION

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Mitochondrial Localization of PARP-1 Requires Interaction with Mitofilin and Is Involved in the Maintenance of Mitochondrial DNA Integrity

(2009) Marianna N. Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein promiscuity and its implications for biotechnology

(2009) Irene Nobeli et al.   NATURE BIOTECHNOLOGY

A census of human transcription factors: function, expression and evolution

(2009) Juan M. Vaquerizas et al.   NATURE REVIEWS GENETICS

Protein abundance profiling of the Escherichia coli cytosol

(2008) Yasushi Ishihama et al.   BMC GENOMICS

An integrated platform of genomic assays reveals small-molecule bioactivities

(2008) Shawn Hoon et al.   Nature Chemical Biology

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Genome-wide analysis of cancer/testis gene expression

(2008) O. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA