Accelerating neuronal aging in in vitro model brain disorders: a focus on reactive oxygen species

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

(2014) Saul A Villeda et al.   NATURE MEDICINE

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

(2014) L. Katsimpardi et al.   SCIENCE

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

(2014) Namrata Chaudhari et al.   Frontiers in Cellular Neuroscience

New Insights on NOX Enzymes in the Central Nervous System

(2013) Zeynab Nayernia et al.   ANTIOXIDANTS & REDOX SIGNALING

Induction of senescence by adenosine suppressing the growth of lung cancer cells

(2013) Dongqin Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolic triad in brain aging: mitochondria, insulin/IGF-1 signalling and JNK signalling: Figure 1

(2013) Fei Yin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

(2013) Justine D. Miller et al.   Cell Stem Cell

Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development

(2013) Cory R. Nicholas et al.   Cell Stem Cell

Electrophysiological intermediate biomarkers for oxidative stress in schizophrenia

(2013) Alejandro Ballesteros et al.   CLINICAL NEUROPHYSIOLOGY

Reactive oxygen species and the free radical theory of aging

(2013) Stefan I. Liochev   FREE RADICAL BIOLOGY AND MEDICINE

Reactive Oxygen Species in the Immune System

(2013) Yuhui Yang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

(2013) Yingsha Zhang et al.   NEURON

Parkinson's disease in a dish – Using stem cells as a molecular tool

(2013) J.L. Badger et al.   NEUROPHARMACOLOGY

ROS and Brain Diseases: The Good, the Bad, and the Ugly

(2013) Aurel Popa-Wagner et al.   Oxidative Medicine and Cellular Longevity

Accelerated Brain Aging in Schizophrenia and Beyond: A Neuroanatomical Marker of Psychiatric Disorders

(2013) N. Koutsouleris et al.   SCHIZOPHRENIA BULLETIN

Role of Redox Signaling in Neuroinflammation and Neurodegenerative Diseases

(2013) Hsi-Lung Hsieh et al.   Biomed Research International

Redox Dysregulation in the Pathophysiology of Schizophrenia and Bipolar Disorder: Insights from Animal Models

(2012) Anita Kulak et al.   ANTIOXIDANTS & REDOX SIGNALING

Functional Consequences of Age-Dependent Changes in Glutathione Status in the Brain

(2012) Antonio Currais et al.   ANTIOXIDANTS & REDOX SIGNALING

Testing the Hypothesis of Accelerated Cerebral White Matter Aging in Schizophrenia and Major Depression

(2012) Peter Kochunov et al.   BIOLOGICAL PSYCHIATRY

Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA

(2012) H.-J. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling human cortical development in vitro using induced pluripotent stem cells

(2012) J. Mariani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease

(2012) O. Cooper et al.   Science Translational Medicine

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

(2012) Xavier Nissan et al.   Cell Reports

Reduced antioxidant defense in early onset first-episode psychosis: a case-control study

(2011) Juan Antonio Micó et al.   BMC Psychiatry

LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress

(2011) Ha Nam Nguyen et al.   Cell Stem Cell

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

(2011) Janel E. Le Belle et al.   Cell Stem Cell

Altered Oxygen Metabolism Associated to Neurogenesis of Induced Pluripotent Stem Cells Derived from a Schizophrenic Patient

(2011) Bruna Da Silveira Paulsen et al.   CELL TRANSPLANTATION

Aging Neural Progenitor Cells Have Decreased Mitochondrial Content and Lower Oxidative Metabolism

(2011) Elizabeth A. Stoll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease

(2011) Kazuma Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress

(2011) Blake Byers et al.   PLoS One

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Divergent Trajectories of Physical, Cognitive, and Psychosocial Aging in Schizophrenia

(2011) D. V. Jeste et al.   SCHIZOPHRENIA BULLETIN

The Effects of Nuclear Reprogramming on Mitochondrial DNA Replication

(2011) Richard D. W. Kelly et al.   Stem Cell Reviews and Reports

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

(2010) Cassandra D. Ragnauth et al.   CIRCULATION

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Adenosine Deaminase Modulation of Telomerase Activity and Replicative Senescence in Human CD8 T Lymphocytes

(2010) S. T. Parish et al.   JOURNAL OF IMMUNOLOGY

Rethinking schizophrenia

(2010) Thomas R. Insel   NATURE

Oxidative stress in schizophrenia: An integrated approach

(2010) Byron K.Y. Bitanihirwe et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Mitochondrial Rejuvenation After Induced Pluripotency

(2010) Steven T. Suhr et al.   PLoS One

Energy metabolism in adult neural stem cell fate

(2010) Victoria A. Rafalski et al.   PROGRESS IN NEUROBIOLOGY

Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells

(2010) Lyle Armstrong et al.   STEM CELLS

Normal human aging and early-stage schizophrenia share common molecular profiles

(2009) Bin Tang et al.   AGING CELL

Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells

(2009) Rosa M. Marion et al.   Cell Stem Cell

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

(2009) Krishanu Saha et al.   Cell Stem Cell

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Age-related expression of adenosine receptors in brain from the senescence-accelerated mouse

(2009) C.A. Castillo et al.   EXPERIMENTAL GERONTOLOGY

Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patients

(2009) Gabriela Viteri et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Differentiation of spinal motor neurons from pluripotent human stem cells

(2009) Bao-Yang Hu et al.   Nature Protocols

A highly reproducible rotenone model of Parkinson's disease

(2009) Jason R. Cannon et al.   NEUROBIOLOGY OF DISEASE

Telomere Length and Pulse Pressure in Newly Diagnosed, Antipsychotic-Naive Patients With Nonaffective Psychosis

(2009) E. Fernandez-Egea et al.   SCHIZOPHRENIA BULLETIN

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES

Adenosine as a neuromodulator in neurological diseases

(2007) D BOISON   CURRENT OPINION IN PHARMACOLOGY

Is Schizophrenia a Syndrome of Accelerated Aging?

(2007) B. Kirkpatrick et al.   SCHIZOPHRENIA BULLETIN