Regulatory T cells in gastrointestinal tumors

Pilot Study of Sentinel-Node-Based Adoptive Immunotherapy in Advanced Colorectal Cancer

(2010) Mona Karlsson et al.   ANNALS OF SURGICAL ONCOLOGY

Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress

(2010) D. Mougiakakos et al.   BLOOD

Selective Depletion of CD4+CD25+Foxp3+Regulatory T Cells by Low-Dose Cyclophosphamide Is Explained by Reduced Intracellular ATP Levels

(2010) Jie Zhao et al.   CANCER RESEARCH

Analysis of the T-Cell Receptor Repertoires of Tumor-Infiltrating Conventional and Regulatory T Cells Reveals No Evidence for Conversion in Carcinogen-Induced Tumors

(2010) J. P. Hindley et al.   CANCER RESEARCH

Conditional Regulatory T-Cell Depletion Releases Adaptive Immunity Preventing Carcinogenesis and Suppressing Established Tumor Growth

(2010) M. W. L. Teng et al.   CANCER RESEARCH

Accumulation of Foxp3+ T Regulatory Cells in Draining Lymph Nodes Correlates with Disease Progression and Immune Suppression in Colorectal Cancer Patients

(2010) L. Deng et al.   CLINICAL CANCER RESEARCH

Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients

(2010) J. F. M. Jacobs et al.   CLINICAL CANCER RESEARCH

CD4+FOXP3+ regulatory T cell depletion by low-dose cyclophosphamide prevents recurrence in patients with large condylomata acuminata after laser therapy

(2010) Yuchun Cao et al.   CLINICAL IMMUNOLOGY

Tumour-infiltrating lymphocytes and survival in patients with adenocarcinoma of the oesophagus

(2010) U. Zingg et al.   EJSO

Local recall responses in the stomach involving reduced regulation and expanded help mediate vaccine-induced protection against Helicobacter pylori in mice

(2010) Dorit Becher et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Efficient Treg depletion induces T-cell infiltration and rejection of large tumors

(2010) Xingrui Li et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Foxp3+ T Cells Induce Perforin-Dependent Dendritic Cell Death in Tumor-Draining Lymph Nodes

(2010) Alexandre Boissonnas et al.   IMMUNITY

Therapeutic cancer vaccines: are we there yet?

(2010) Christopher A. Klebanoff et al.   IMMUNOLOGICAL REVIEWS

Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes

(2010) Gerald Wirnsberger et al.   IMMUNOLOGY AND CELL BIOLOGY

Higher intratumoral infiltrated Foxp3+ Treg numbers and Foxp3+/CD8+ ratio are associated with adverse prognosis in resectable gastric cancer

(2010) Zhengbin Shen et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Phase II Study of the Anti-Cytotoxic T-Lymphocyte–Associated Antigen 4 Monoclonal Antibody, Tremelimumab, in Patients With Refractory Metastatic Colorectal Cancer

(2010) Ki Y. Chung et al.   JOURNAL OF CLINICAL ONCOLOGY

Successful Colon Cancer Eradication after Chemoimmunotherapy Is Associated with Profound Phenotypic Change of Intratumoral Myeloid Cells

(2010) J. Medina-Echeverz et al.   JOURNAL OF IMMUNOLOGY

Depletion of Regulatory T Cells Facilitates Growth of Established Tumors: A Mechanism Involving the Regulation of Myeloid-Derived Suppressor Cells by Lipoxin A4

(2010) B. Zhang et al.   JOURNAL OF IMMUNOLOGY

Stimulation of the Glucocorticoid-Induced TNF Receptor Family-Related Receptor on CD8 T Cells Induces Protective and High-Avidity T Cell Responses to Tumor-Specific Antigens

(2010) A. L. Cote et al.   JOURNAL OF IMMUNOLOGY

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Regulatory (FoxP3+) T-cell Tumor Infiltration Is a Favorable Prognostic Factor in Advanced Colon Cancer Patients Undergoing Chemo or Chemoimmunotherapy

(2010) Pierpaolo Correale et al.   JOURNAL OF IMMUNOTHERAPY

IL-35-mediated induction of a potent regulatory T cell population

(2010) Lauren W Collison et al.   NATURE IMMUNOLOGY

Extracellular adenosine triphosphate and adenosine in cancer

(2010) J Stagg et al.   ONCOGENE

Intratumoral Convergence of the TCR Repertoires of Effector and Foxp3+ CD4+ T cells

(2010) Michal Kuczma et al.   PLoS One

In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction

(2010) N. R. Blatner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intratumoral CD8+ T/FOXP3+ cell ratio is a predictive marker for survival in patients with colorectal cancer

(2009) Hiroyuki Suzuki et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Ipilimumab: controversies in its development, utility and autoimmune adverse events

(2009) Jeffrey Weber   CANCER IMMUNOLOGY IMMUNOTHERAPY

Differences in Tumor Regulatory T-Cell Localization and Activation Status Impact Patient Outcome

(2009) C. Menetrier-Caux et al.   CANCER RESEARCH

T-Regulatory Cells Shift from a Protective Anti-Inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis

(2009) Elias Gounaris et al.   CANCER RESEARCH

Increased Ectonucleotidase Expression and Activity in Regulatory T Cells of Patients with Head and Neck Cancer

(2009) M. Mandapathil et al.   CLINICAL CANCER RESEARCH

A Novel Synergistic Combination of Cyclophosphamide and Gene Transfer of Interleukin-12 Eradicates Colorectal Carcinoma in Mice

(2009) M. Malvicini et al.   CLINICAL CANCER RESEARCH

Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner

(2009) Xiang-Liang Yuan et al.   CLINICAL IMMUNOLOGY

Expression of FOXP3 in esophageal squamous cell carcinoma relating to the clinical data

(2009) L. Xue et al.   DISEASES OF THE ESOPHAGUS

Influence of neoadjuvant radio-chemotherapy on tumor-infiltrating lymphocytes in squamous esophageal cancer

(2009) U. Zingg et al.   EJSO

Intraepithelial Effector (CD3+)/Regulatory (FoxP3+) T-Cell Ratio Predicts a Clinical Outcome of Human Colon Carcinoma

(2009) Frank A. Sinicrope et al.   GASTROENTEROLOGY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Interleukin-35: odd one out or part of the family?

(2009) Lauren W. Collison et al.   IMMUNOLOGICAL REVIEWS

Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion

(2009) Makoto Miyara et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Naturally occurring regulatory T cells show reduced sensitivity toward oxidative stress-induced cell death

(2008) D. Mougiakakos et al.   BLOOD

Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines

(2008) M. A. Morse et al.   BLOOD

High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability

(2008) S Michel et al.   BRITISH JOURNAL OF CANCER

Infiltrating regulatory T cell numbers is not a factor to predict patient's survival in oesophageal squamous cell carcinoma

(2008) T Yoshioka et al.   BRITISH JOURNAL OF CANCER

Ability of Mature Dendritic Cells to Interact with Regulatory T Cells Is Imprinted during Maturation

(2008) R. Muthuswamy et al.   CANCER RESEARCH

TGFβ in Cancer

(2008) Joan Massagué   CELL

Pathologic Complete Response to Neoadjuvant Chemotherapy of Breast Carcinoma Is Associated with the Disappearance of Tumor-Infiltrating Foxp3+ Regulatory T Cells

(2008) S. Ladoire et al.   CLINICAL CANCER RESEARCH

The critical contribution of TGF-β to the induction of Foxp3 expression and regulatory T cell function

(2008) Ethan M. Shevach et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A New Population of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Induces CD4+CD25+Foxp3+ T Cells

(2008) Bastian Hoechst et al.   GASTROENTEROLOGY

Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells

(2008) Ilaria Marigo et al.   IMMUNOLOGICAL REVIEWS

Role of Endogenous and Induced Regulatory T Cells During Infections

(2008) Elizabeth Wohlfert et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

(2008) Paul Salama et al.   JOURNAL OF CLINICAL ONCOLOGY

Small intestinal CD103+dendritic cells display unique functional properties that are conserved between mice and humans

(2008) Elin Jaensson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE

Macrophage polarization in tumour progression

(2008) Antonio Sica et al.   SEMINARS IN CANCER BIOLOGY

T-cell recruitment to the intestinal mucosa

(2008) William W. Agace   TRENDS IN IMMUNOLOGY

High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas

(2007) S Le Gouvello et al.   GUT