Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 6, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-03-09
DOI
10.3389/fphar.2015.00032
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Trypanosoma bruceieflornithine transporter AAT6 is a low-affinity low-selective transporter for neutral amino acids
- (2014) Christoph Mathieu et al. BIOCHEMICAL JOURNAL
- Cyclical Appearance of African Trypanosomes in the Cerebrospinal Fluid: New Insights in How Trypanosomes Enter the CNS
- (2014) Stefan Mogk et al. PLoS One
- Melarsoprol Sensitivity Profile of Trypanosoma brucei gambiense Isolates from Cured and Relapsed Sleeping Sickness Patients from the Democratic Republic of the Congo
- (2014) Patient Pyana Pati et al. PLoS Neglected Tropical Diseases
- Aquaporins with anion/monocarboxylate permeability: mechanisms, relevance for pathogen–host interactions
- (2014) Janis Rambow et al. Frontiers in Pharmacology
- Parasite aquaporins: Current developments in drug facilitation and resistance
- (2013) Jie Song et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Trypanosoma Brucei Aquaglyceroporins Facilitate the Uptake of Arsenite and Antimonite in a pH Dependent Way
- (2013) Néstor L. Uzcátegui et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs
- (2013) J. C. Munday et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Structure–Activity Relationships of Synthetic Cordycepin Analogues as Experimental Therapeutics for African Trypanosomiasis
- (2013) Suman K. Vodnala et al. JOURNAL OF MEDICINAL CHEMISTRY
- Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy
- (2013) Sam Alsford et al. TRENDS IN PARASITOLOGY
- Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story
- (2013) Nicola Baker et al. TRENDS IN PARASITOLOGY
- Aquaporin 2 Mutations in Trypanosoma brucei gambiense Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol
- (2013) Fabrice E. Graf et al. PLoS Neglected Tropical Diseases
- Trypanosoma evansiand Surra: A Review and Perspectives on Origin, History, Distribution, Taxonomy, Morphology, Hosts, and Pathogenic Effects
- (2013) Marc Desquesnes et al. Biomed Research International
- Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake
- (2013) Jane C. Munday et al. International Journal for Parasitology-Drugs and Drug Resistance
- FRED and HYBRID docking performance on standardized datasets
- (2012) Mark McGann JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis
- (2012) P. P. SIMARRO et al. PARASITOLOGY
- Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes
- (2012) N. Baker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Widespread occurrence of Trypanosoma vivax in bovines of tsetse- as well as non-tsetse-infested regions of Ethiopia: A reason for concern?
- (2012) Regassa Fikru et al. VETERINARY PARASITOLOGY
- Trypanocidal Furamidine Analogues: Influence of Pyridine Nitrogens on Trypanocidal Activity, Transport Kinetics, and Resistance Patterns
- (2011) Christopher P. Ward et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Functional Characterization of Three Aquaglyceroporins from Trypanosoma brucei in Osmoregulation and Glycerol Transport
- (2011) Björn Bassarak et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Enhancement of Proton Conductance by Mutations of the Selectivity Filter of Aquaporin-1
- (2011) Hui Li et al. JOURNAL OF MOLECULAR BIOLOGY
- Specializations in a successful parasite: What makes the bloodstream-form African trypanosome so deadly?
- (2011) Catarina Gadelha et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- The Diamidine Diminazene Aceturate Is a Substrate for the High-Affinity Pentamidine Transporter: Implications for the Development of High Resistance Levels in Trypanosomes
- (2011) I. A. Teka et al. MOLECULAR PHARMACOLOGY
- How to Shorten Patient Follow‐Up after Treatment forTrypanosoma brucei gambienseSleeping Sickness
- (2010) Dieudonné Mumba Ngoyi et al. JOURNAL OF INFECTIOUS DISEASES
- Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6
- (2010) Nicola Baker et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters
- (2010) Gabriela Schumann Burkard et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Trypanosoma brucei: two steps to spread out from Africa
- (2010) Zhao-Rong Lun et al. TRENDS IN PARASITOLOGY
- A Molecular Mechanism for Eflornithine Resistance in African Trypanosomes
- (2010) Isabel M. Vincent et al. PLoS Pathogens
- Predictive Computational Models of Substrate Binding by a Nucleoside Transporter
- (2009) Catharine J. Collar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial
- (2009) Gerardo Priotto et al. LANCET
- Human African trypanosomiasis
- (2009) Reto Brun et al. LANCET
- Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum
- (2008) Zachary E R Newby et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The history of African trypanosomiasis
- (2008) Dietmar Steverding Parasites & Vectors
- Molecular tools for the rapid detection of drug resistance in animal trypanosomes
- (2008) Vincent Delespaux et al. TRENDS IN PARASITOLOGY
- Ever-increasing complexities of diamidine and arsenical crossresistance in African trypanosomes
- (2008) Harry P. de Koning TRENDS IN PARASITOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now