- Home
- Publications
- Publication Search
- Publication Details
Title
Therapeutic potential of mGluR5 targeting in Alzheimer's disease
Authors
Keywords
-
Journal
Frontiers in Neuroscience
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-06-09
DOI
10.3389/fnins.2015.00215
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- M1 and M2 immune activation in Parkinson’s Disease: Foe and ally?
- (2015) M.S. Moehle et al. NEUROSCIENCE
- Glutamate receptors function as scaffolds for the regulation of β-amyloid and cellular prion protein signaling complexes
- (2015) Alison Hamilton et al. Molecular Brain
- Microglial dysfunction in brain aging and Alzheimer's disease
- (2014) Kira Irving Mosher et al. BIOCHEMICAL PHARMACOLOGY
- Human CNS immune senescence and neurodegeneration
- (2014) Wolfgang J Streit et al. CURRENT OPINION IN IMMUNOLOGY
- Targeting microglia for the treatment of Alzheimer’s disease
- (2014) Patrick L McGeer et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed
- (2014) Jonathan D Cherry et al. Journal of Neuroinflammation
- Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5 – implications for dementia with Lewy bodies
- (2014) Cassia R Overk et al. Molecular Neurodegeneration
- Metabotropic glutamate receptor 5 modulates calcium oscillation and innate immune response induced by lipopolysaccharide in microglial cell
- (2014) F. Liu et al. NEUROSCIENCE
- mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo
- (2014) Neng-Wei Hu et al. Nature Communications
- Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease
- (2014) Alison Hamilton et al. Molecular Brain
- From development to dysfunction: Microglia and the complement cascade in CNS homeostasis
- (2013) Matthew K. Zabel et al. AGEING RESEARCH REVIEWS
- β-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptors
- (2013) Amulya Nidhi Shrivastava et al. GLIA
- Amyloid beta deregulates astroglial mGluR5-mediated calcium signaling via calcineurin and Nf-kB
- (2013) Dmitry Lim et al. GLIA
- Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein
- (2013) Ji Won Um et al. NEURON
- Donepezil inhibits the amyloid-beta oligomer-induced microglial activation in vitro and in vivo
- (2013) Hyo Geun Kim et al. NEUROTOXICOLOGY
- Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity
- (2013) Andrew J. Nicoll et al. Nature Communications
- Isolated Amyloid-β(1–42) Protofibrils, But Not Isolated Fibrils, Are Robust Stimulators of Microglia
- (2012) Geeta S. Paranjape et al. ACS Chemical Neuroscience
- Alzheimer's disease and Down's syndrome: Treating two paths to dementia
- (2012) Marc E. Weksler et al. AUTOIMMUNITY REVIEWS
- Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
- (2012) Bing Liao et al. EXPERIMENTAL NEUROLOGY
- Unraveling the Early Events of Amyloid-β Protein (Aβ) Aggregation: Techniques for the Determination of Aβ Aggregate Size
- (2012) N. Elizabeth Pryor et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer’s disease
- (2012) Magdalena Kulijewicz-Nawrot et al. JOURNAL OF ANATOMY
- Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
- (2012) Hyejung Won et al. NATURE
- Opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes
- (2012) J.V. Berger et al. NEUROSCIENCE
- Neoechinulin A suppresses amyloid-β oligomer-induced microglia activation and thereby protects PC-12 cells from inflammation-mediated toxicity
- (2012) Pradeep Dewapriya et al. NEUROTOXICOLOGY
- 2011 Alzheimer’s disease facts and figures
- (2011) Alzheimers & Dementia
- Early Astrocytic Atrophy in the Entorhinal Cortex of a Triple Transgenic Animal Model of Alzheimer's Disease
- (2011) Chia-Yu Yeh et al. ASN Neuro
- β-amyloid activates PARP causing astrocytic metabolic failure and neuronal death
- (2011) Rosella Abeti et al. BRAIN
- New developments on the role of NMDA receptors in Alzheimer's disease
- (2011) Roberto Malinow CURRENT OPINION IN NEUROBIOLOGY
- Amyloid -Induced Death in Neurons Involves Glial and Neuronal Hemichannels
- (2011) J. A. Orellana et al. JOURNAL OF NEUROSCIENCE
- Cross talk between activation of microglia and astrocytes in pathological conditions in the central nervous system
- (2011) W. Liu et al. LIFE SCIENCES
- A prolonged pharmacological blockade of type-5 metabotropic glutamate receptors protects cultured spinal cord motor neurons against excitotoxic death
- (2011) Simona D'Antoni et al. NEUROBIOLOGY OF DISEASE
- The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease
- (2011) Sergio T. Ferreira et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- mGluR5 and NMDA Receptors Drive the Experience- and Activity-Dependent NMDA Receptor NR2B to NR2A Subunit Switch
- (2011) Jose A. Matta et al. NEURON
- Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices
- (2011) Gerhard Rammes et al. NEUROPHARMACOLOGY
- Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites
- (2011) Darragh B. Freir et al. Nature Communications
- NovelN-methyl-d-aspartate receptor antagonists: a review of compounds patented since 2006
- (2010) Manuel Koller et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- The prion protein as a receptor for amyloid-β
- (2010) Helmut W. Kessels et al. NATURE
- Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5
- (2010) Marianne Renner et al. NEURON
- Astrocytes in Alzheimer’s disease
- (2010) Alexei Verkhratsky et al. Neurotherapeutics
- Synthetic amyloid- oligomers impair long-term memory independently of cellular prion protein
- (2010) C. Balducci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Up-regulation of astrocyte metabotropic glutamate receptor 5 by amyloid-β peptide
- (2009) Christopher S. Casley et al. BRAIN RESEARCH
- Picomolar Amyloid- Positively Modulates Synaptic Plasticity and Memory in Hippocampus
- (2009) D. Puzzo et al. JOURNAL OF NEUROSCIENCE
- Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
- (2009) K. A. Kigerl et al. JOURNAL OF NEUROSCIENCE
- Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers
- (2009) Juha Laurén et al. NATURE
- Systemic inflammation and disease progression in Alzheimer disease
- (2009) C. Holmes et al. NEUROLOGY
- Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice
- (2009) K. V. Kuchibhotla et al. SCIENCE
- Cognitive Function Over Time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT)
- (2008) ARCHIVES OF NEUROLOGY
- Memantine protects rat cortical cultured neurons against β-amyloid-induced toxicity by attenuating tau phosphorylation
- (2008) M. S. Song et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity
- (2008) Kimberly R. Byrnes et al. GLIA
- Structural Classification of Toxic Amyloid Oligomers
- (2008) Charles G. Glabe JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started