Potential application of lithium in Parkinson's and other neurodegenerative diseases

Long-Term Treatment with Lithium Alleviates Memory Deficits and Reduces Amyloid-β Production in an Aged Alzheimer's Disease Transgenic Mouse Model

(2018) Xin Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

The combination of lithium and l-Dopa/Carbidopa reduces MPTP-induced abnormal involuntary movements (AIMs) via calpain-1 inhibition in a mouse model: Relevance for Parkinson׳s disease therapy

(2015) Carol A. Lazzara et al.   BRAIN RESEARCH

Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells

(2015) Begum Alural et al.   Frontiers in Cellular Neuroscience

Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium

(2014) Francesco Fornai et al.   Autophagy

Role of zinc and copper ions in the pathogenetic mechanisms of Alzheimer’s and Parkinson’s diseases

(2014) E. V. Stelmashook et al.   BIOCHEMISTRY-MOSCOW

Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model

(2014) Christopher A. Lieu et al.   BRAIN RESEARCH

Specific Inhibition of p25/Cdk5 Activity by the Cdk5 Inhibitory Peptide Reduces Neurodegeneration In Vivo

(2013) J. R. Sundaram et al.   JOURNAL OF NEUROSCIENCE

Off label use of lithium in the treatment of Huntington′s disease: A case series

(2013) Vijay Danivas et al.   Indian Journal of Psychiatry

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Neuroprotective effects of chronic exposure of SH-SY5Y to low lithium concentration involve glycolysis stimulation, extracellular pyruvate accumulation and resistance to oxidative stress

(2012) Riadh Nciri et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Therapeutic Effects of Valproate Combined With Lithium Carbonate on MPTP-Induced Parkinsonism in Mice: Possible Mediation Through Enhanced Autophagy

(2012) Xue-zhong Li et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Lithium enhances remyelination of peripheral nerves

(2012) J. Makoukji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: randomised controlled trial

(2011) Orestes V. Forlenza et al.   BRITISH JOURNAL OF PSYCHIATRY

Lithium protects against oxidative stress-mediated cell death in α-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease

(2011) Yong-Hwan Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Phase II screening trial of lithium carbonate in amyotrophic lateral sclerosis: Examining a more efficient trial design

(2011) R. G. Miller et al.   NEUROLOGY

Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice

(2011) Olivia F. O’Leary et al.   NEUROPHARMACOLOGY

Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's Disease

(2011) Chi-Tso Chiu et al.   NEUROPSYCHOPHARMACOLOGY

Neuroprotective effect and cognitive outcome of chronic lithium on traumatic brain injury in mice

(2010) Zu-Fu Zhu et al.   BRAIN RESEARCH BULLETIN

Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease

(2010) Akira Yoshii et al.   Developmental Neurobiology

Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

(2010) Swati P Aggarwal et al.   LANCET NEUROLOGY

Lithium carbonate in amyotrophic lateral sclerosis: Lack of efficacy in a dose-finding trial

(2010) A. Chio et al.   NEUROLOGY

Glutamate receptors, neurotoxicity and neurodegeneration

(2010) Anthony Lau et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Lithium Improves Hippocampal Neurogenesis, Neuropathology and Cognitive Functions in APP Mutant Mice

(2010) Anna Fiorentini et al.   PLoS One

α-Synuclein contributes to GSK-3β-catalyzed Tau phosphorylation in Parkinson’s disease models

(2009) Tetyana Duka et al.   FASEB JOURNAL

Lithium Trial in Alzheimer's Disease

(2009) Harald Hampel et al.   JOURNAL OF CLINICAL PSYCHIATRY

Lithium enhances the neuronal differentiation of neural progenitor cellsin vitroand after transplantation into the avulsed ventral horn of adult rats through the secretion of brain-derived neurotrophic factor

(2009) Huanxing Su et al.   JOURNAL OF NEUROCHEMISTRY

Glutathione and Parkinson's disease: Is this the elephant in the room?

(2008) Gail D. Zeevalk et al.   BIOMEDICINE & PHARMACOTHERAPY

Small molecule enhancers of autophagy for neurodegenerative diseases

(2008) Sovan Sarkar et al.   Molecular BioSystems

Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro

(2008) N. Crespo-Biel et al.   NEUROPHARMACOLOGY

Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model

(2008) H.-L. Feng et al.   NEUROSCIENCE

Pruning and loss of excitatory synapses by the parkin ubiquitin ligase

(2008) T. D. Helton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lithium delays progression of amyotrophic lateral sclerosis

(2008) F. Fornai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling

(2007) Min-Huei Liang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE