Challenges in translational research on probiotic lactobacilli: from in vitro assays to clinical trials

Characterization of Candidate Anti-Allergic Probiotic Strains in a Model of Th2-Skewed Human Peripheral Blood Mononuclear Cells

(2013) Sébastien Holvoet et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines

(2012) Marie-Anne von Schillde et al.   Cell Host & Microbe

The induction of Treg cells by gut-indigenous Clostridium

(2012) Yuji Nagano et al.   CURRENT OPINION IN IMMUNOLOGY

Immunomodulatory effects of potential probiotics in a mouse peanut sensitization model

(2012) Marjolein Meijerink et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Lactobacillus plantarum possesses the capability for wall teichoic acid backbone alditol switching

(2012) Peter A Bron et al.   Microbial Cell Factories

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Microbiota/Host Crosstalk Biomarkers: Regulatory Response of Human Intestinal Dendritic Cells Exposed to Lactobacillus Extracellular Encrypted Peptide

(2012) David Bernardo et al.   PLoS One

Mucosal Vaccination and Therapy with Genetically Modified Lactic Acid Bacteria

(2012) Jerry Wells   Annual Review of Food Science and Technology

Asthma Prevention byLactobacillus Rhamnosusin a Mouse Model is Associated With CD4+CD25+Foxp3+T Cells

(2012) Seong-Ok Jang et al.   Allergy Asthma & Immunology Research

Lactobacillus GG as an immune adjuvant for live-attenuated influenza vaccine in healthy adults: a randomized double-blind placebo-controlled trial

(2011) L E Davidson et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Health benefits of probiotics: are mixtures more effective than single strains?

(2011) C. M. C. Chapman et al.   EUROPEAN JOURNAL OF NUTRITION

Infant gut microbiota is protective against cow's milk allergy in mice despite immature ileal T-cell response

(2011) Bertrand Rodriguez et al.   FEMS MICROBIOLOGY ECOLOGY

Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease

(2011) Clara Abraham et al.   GASTROENTEROLOGY

Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide

(2011) E. M. Fernandez et al.   GUT

Consumption of probiotics increases the effect of regulatory T cells in transfer colitis

(2011) Emil Rathsach Petersen et al.   INFLAMMATORY BOWEL DISEASES

Cryopreservation of monocytes or differentiated immature DCs leads to an altered cytokine response to TLR agonists and microbial stimulation

(2011) Marjolein Meijerink et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Antifoam addition to shake flask cultures of recombinant Pichia pastoris increases yield

(2011) Sarah J Routledge et al.   Microbial Cell Factories

Lysate of Probiotic Lactobacillus casei DN-114 001 Ameliorates Colitis by Strengthening the Gut Barrier Function and Changing the Gut Microenvironment

(2011) Zuzana Zakostelska et al.   PLoS One

Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid

(2011) M. Mohamadzadeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

(2010) Jurgen Karczewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A candidate probiotic with unfavourable effects in subjects with irritable bowel syndrome: a randomised controlled trial

(2010) Solveig C Ligaarden et al.   BMC GASTROENTEROLOGY

Impact of lipoteichoic acid modification on the performance of the probiotic Lactobacillus rhamnosus GG in experimental colitis

(2010) I. J. J. Claes et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

(2010) H. Okada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Enteric Flora Expands Gut Lamina Propria CX 3 CR1 + Dendritic Cells Supporting Inflammatory Immune Responses under Normal and Inflammatory Conditions

(2010) Jan Hendrik Niess et al.   JOURNAL OF IMMUNOLOGY

Guidance for Substantiating the Evidence for Beneficial Effects of Probiotics: Probiotics in Chronic Inflammatory Bowel Disease and the Functional Disorder Irritable Bowel Syndrome

(2010) Dirk Haller et al.   JOURNAL OF NUTRITION

Guidance for Substantiating the Evidence for Beneficial Effects of Probiotics: Prevention and Management of Allergic Diseases by Probiotics

(2010) Marko Kalliomäki et al.   JOURNAL OF NUTRITION

Guidance for Substantiating the Evidence for Beneficial Effects of Probiotics: Current Status and Recommendations for Future Research

(2010) Ger T. Rijkers et al.   JOURNAL OF NUTRITION

Intranasal administration of Lactobacillus rhamnosus GG protects mice from H1N1 influenza virus infection by regulating respiratory immune responses

(2010) G. Harata et al.   LETTERS IN APPLIED MICROBIOLOGY

A Three-Dimensional Coculture of Enterocytes, Monocytes and Dendritic Cells To Model Inflamed Intestinal Mucosa in Vitro

(2010) Fransisca Leonard et al.   MOLECULAR PHARMACEUTICS

Adaptive immunity in the host–microbiota dialog

(2010) T Feng et al.   Mucosal Immunology

Organotypic 3D cell culture models: using the rotating wall vessel to study host–pathogen interactions

(2010) Jennifer Barrila et al.   NATURE REVIEWS MICROBIOLOGY

Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens

(2010) Sarah Lebeer et al.   NATURE REVIEWS MICROBIOLOGY

The probiotic paradox: live and dead cells are biological response modifiers

(2010) Clifford A. Adams   NUTRITION RESEARCH REVIEWS

Lactobacillus GG in the Prevention of Nosocomial Gastrointestinal and Respiratory Tract Infections

(2010) I. Hojsak et al.   PEDIATRICS

A Novel Probiotic Mixture Exerts a Therapeutic Effect on Experimental Autoimmune Encephalomyelitis Mediated by IL-10 Producing Regulatory T Cells

(2010) Shahram Lavasani et al.   PLoS One

Identification of Genetic Loci in Lactobacillus plantarum That Modulate the Immune Response of Dendritic Cells Using Comparative Genome Hybridization

(2010) Marjolein Meijerink et al.   PLoS One

Epithelial crosstalk at the microbiota-mucosal interface

(2010) J. M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders

(2010) H.-K. Kwon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Probiotic modulation of dendritic cells and T cell responses in the intestine

(2010) M. Meijerink et al.   Beneficial Microbes

Protection of Mice against Lethal Challenge with 2009 H1N1 Influenza A Virus by 1918-Like and Classical Swine H1N1 Based Vaccines

(2010) Balaji Manicassamy et al.   PLoS Pathogens

Oral intake of Lactobacillus pentosus strain b240 accelerates salivary immunoglobulin A secretion in the elderly: A randomized, placebo-controlled, double-blind trial

(2010) Yoshifumi Kotani et al.   Immunity & Ageing

Heterogeneity of S-layer proteins from aggregating and non-aggregating Lactobacillus kefir strains

(2009) Pablo Mobili et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Translational Mini-Review Series on Th17 Cells: Function and regulation of human T helper 17 cells in health and disease

(2009) S. Q. Crome et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells

(2009) I D Iliev et al.   GUT

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Probiotic microbes: do they need to be alive to be beneficial?

(2009) Jasmeet Kataria et al.   NUTRITION REVIEWS

Oral Probiotic Control Skin Inflammation by Acting on Both Effector and Regulatory T Cells

(2009) Feriel Hacini-Rachinel et al.   PLoS One

Comparison of the Immunomodulatory Properties of Three Probiotic Strains of Lactobacilli Using Complex Culture Systems: Prediction for In Vivo Efficacy

(2009) Erika Mileti et al.   PLoS One

Detection, Localization, and Conformational Analysis of Single Polysaccharide Molecules on Live Bacteria

(2008) Grégory Francius et al.   ACS Nano

Lactobacillus reuteri–induced Regulatory T cells Protect against an Allergic Airway Response in Mice

(2008) Khalil Karimi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Oral delivery ofLactobacillus caseiShirota modifies allergen-induced immune responses in allergic rhinitis

(2008) K. Ivory et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial

(2008) Damien Paineau et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Commensal DNA Limits Regulatory T Cell Conversion and Is a Natural Adjuvant of Intestinal Immune Responses

(2008) Jason A. Hall et al.   IMMUNITY

Effects of probiotic bacteria and their genomic DNA on TH1/TH2-cytokine production by peripheral blood mononuclear cells (PBMCs) of healthy and allergic subjects

(2008) D GHADIMI et al.   IMMUNOBIOLOGY

A differential effect of 2 probiotics in the prevention of eczema and atopy: A double-blind, randomized, placebo-controlled trial

(2008) Kristin Wickens et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Significant contribution of thepgdAgene to the virulence ofStreptococcus suis

(2008) Nahuel Fittipaldi et al.   MOLECULAR MICROBIOLOGY

Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria

(2008) Jerry M. Wells et al.   NATURE REVIEWS MICROBIOLOGY

Randomized, Double-Blind, Placebo-Controlled Trial of Probiotics for Primary Prevention: No Clinical Effects of Lactobacillus GG Supplementation

(2008) M. V. Kopp et al.   PEDIATRICS

Salmonella Type III Effector AvrA Stabilizes Cell Tight Junctions to Inhibit Inflammation in Intestinal Epithelial Cells

(2008) Anne P. Liao et al.   PLoS One

S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions

(2008) S. R. Konstantinov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation

(2008) Caitlin O'Mahony et al.   PLoS Pathogens

Lactobacillus fermentum ACA-DC 179 displays probiotic potential in vitro and protects against trinitrobenzene sulfonic acid (TNBS)-induced colitis and Salmonella infection in murine models

(2007) Georgia Zoumpopoulou et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Safety assessment of dairy microorganisms: The Lactobacillus genus☆

(2007) M BERNARDEAU et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY