Journal
ADVANCED HEALTHCARE MATERIALS
Volume 7, Issue 20, Pages -Publisher
WILEY
DOI: 10.1002/adhm.201800344
Keywords
fluorescence imaging; in vivo; nanomaterials; self-assembly; transformation
Funding
- National Natural Science Foundation of China [51573032, 51573031]
- National Science Fund for Distinguished Young Scholars [51725302]
- Science Fund for Creative Research Groups of the National Natural Science Foundation of China [11621505]
- CAS Key Research Program for Frontier Sciences [QYZDJ-SSW-SLH022]
- Key Project of Chinese Academy of Sciences in Cooperation with Foreign Enterprises [GJHZ1541]
- CAS Interdisciplinary Innovation Team
- Jilin Province Key Laboratory of Organic Functional Molecular Design and Synthesis [130028649]
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Fluorescent nanomaterials, self-assembled from building blocks through multiple intermolecular interactions show diversified structures and functionalities, and are potential fluorescence contrast agents/probes for high-performance biomedical imaging. Self-assembled nanomaterials exhibit high stability, long circulation time, and targeted biological distribution. This review summarizes recent advances of self-assembled nanomaterials as fluorescence contrast agents/probes for biomedical imaging. The self-assembled nanomaterials are classified into two groups, i.e., ex situ and in situ construction of self-assembled nanomaterials. The advantages of ex situ as well as in situ constructed nanomaterials for biomedical applications are discussed thoroughly. The directions of future developments for self-assembled nanomaterials are provided.
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