Article
Microbiology
Carolina Robertsson, Gunnel Svensater, Julia R. Davies, Anders Bay Nord, Daniel Malmodin, Claes Wickstrom
Summary: Bacterial metabolism in oral biofilms involves complex networks and regulations, including interactions with host components. In this study, it was found that two oral commensal bacteria, S. gordonii and Actinomyces naeslundii, can utilize salivary MUC5B as a nutrient source during early biofilm formation. The presence of S. gordonii promotes the colonization of A. naeslundii on MUC5B, and synergistic effects were observed in the dual species biofilm metabolism.
MICROBIOLOGY SPECTRUM
(2023)
Article
Multidisciplinary Sciences
Daria Ciecholewska-Jusko, Anna Zywicka, Adam Junka, Marta Woroszylo, Marcin Wardach, Grzegorz Chodaczek, Patrycja Szymczyk-Ziolkowska, Pawel Migdal, Karol Fijalkowski
Summary: This study analyzed the increased activity of the antiseptic octenidine dihydrochloride against Staphylococcus aureus and Pseudomonas aeruginosa biofilms under the influence of a rotating magnetic field. The results showed that the magnetic field weakened the biofilm's cell wall and membrane, altered cell morphology, and changed the porosity and composition of the biofilm matrix.
SCIENTIFIC REPORTS
(2022)
Article
Microbiology
Jang-Jih Lu, Hsiu-Jung Lo, Chih-Hua Lee, Mei-Jun Chen, Chih-Chao Lin, Yin-Zhi Chen, Ming-Horng Tsai, Shao-Hung Wang
Summary: This study used MALDI-TOF MS to identify yeast-like microorganisms in the oral washes of non-bedridden nursing home residents. The majority of isolates were Candida species (78.1%). MALDI-TOF MS was verified as a fast, accurate, and practical method for analyzing oral yeasts in elderly subjects.
Article
Chemistry, Multidisciplinary
Chrysoula (Chrysa) Voidarou, Maria Antoniadou, Georgios Rozos, Athanasios Alexopoulos, Elpida Giorgi, Athina Tzora, Ioannis Skoufos, Theodoros Varzakas, Eugenia Bezirtzoglou
Summary: Greek honeys, especially citrus honey and oregano and sage honey, showed better antibacterial activity than manuka honey against all tested bacteria. The enhanced antibacterial effect of the honeys when diluted in artificial saliva compared to distilled water was observed.
APPLIED SCIENCES-BASEL
(2021)
Article
Microbiology
Zoulikha Krimi, Chahrazed Ziouche, Lamia Tafifet, Hafidha Djellout, Fadhela Mohamed-Mahmoud, Aida Raio
Summary: The endophytic strain EHF3 was isolated from Euphorbia helioscopia plant in Algeria and identified as Curtobacterium flaccumfaciens. It exhibited various physiological and biochemical characteristics such as enzyme secretion and growth ability at different temperatures and pH levels. However, it showed limitations in phosphorus solubilization and production of certain compounds. The strain also demonstrated pathogenicity towards tobacco plants and induced symptoms resembling bacterial wilt disease in bean varieties.
CURRENT MICROBIOLOGY
(2023)
Article
Food Science & Technology
Julia Anna Helene Kaeswurm, Rebecca Sempio, Federica Manca, Melanie Regina Burandt, Maria Buchweitz
Summary: This study determined the phenolic contents and profiles of apples and investigated their bioaccessibility during oral digestion. The proposed beneficial effect of PP on variety specific allergenicity was also discussed.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Hui Yang, Yingying Hou, Yujie Pan, Tingting Zhang, Qi Meng, Jianzhong Han, Weilin Liu, Daofeng Qu
Summary: Chewing ability and rice variety have an impact on the properties of the mixture, gastric emptying, and the degree of starch hydrolysis.
Article
Infectious Diseases
Adriana Barbosa Ribeiro, Aline Barbosa Ribeiro, Camila Borba de Araujo, Caroline Vieira Fortes, Lorena Mosconi Clemente, Helena de Freitas Oliveira Paranhos, Evandro Watanabe, Helio Cesar Salgado, Claudia Helena Silva-Lovato
Summary: This study evaluated the effectiveness of a hygiene protocol on denture-related stomatitis (DRS). The results showed that the protocol reduced the inflammation degree of DRS, improved local inflammatory factors, and reduced patients' blood pressure.
Review
Biochemistry & Molecular Biology
Maaike Waasdorp, Bastiaan P. Krom, Floris J. Bikker, Paul P. M. van Zuijlen, Frank B. Niessen, Susan Gibbs
Summary: Oral mucosa heals faster, shows a more rapid immune response, and undergoes increased extracellular matrix remodeling compared to skin, leading to superior wound healing and reduced scar formation.
Article
Biotechnology & Applied Microbiology
Chloe M. Wu, Kelsey M. Wheeler, Gerardo Carcamo-Oyarce, Kazuhiro Aoki, Abigail McShane, Sujit S. Datta, Jessica L. Mark Welch, Michael Tiemeyer, Ann L. Griffen, Katharina Ribbeck
Summary: Human microbiome composition is influenced by the natural host environment, specifically mucus, which contains gel-forming glycoproteins (mucins) with regulatory functions. Mucin glycans enable the coexistence of diverse microbes and prevent disease-associated compositional shifts. Different glycosylation patterns of mucins shape microbial communities by providing nutrients, organizing spatial structure, and potentially limiting competition. This study highlights the importance of mucin glycans as a host mechanism and potential therapeutic approach for maintaining a healthy microbiome.
NPJ BIOFILMS AND MICROBIOMES
(2023)
Article
Multidisciplinary Sciences
Tommy Baumann, Samira Helena Niemeyer, Marilia Afonso Rabelo Buzalaf, Thiago Saads Carvalho
Summary: Unlike pellicles formed in vivo, pellicles formed in vitro provide little protection against enamel erosion, which may result from protein degradation caused by proteases during pellicle formation. This study investigated the effects of adding protease inhibitors (PI) to saliva and/or exchanging saliva during pellicle formation on the erosion protection of human enamel specimens in a cyclic model. The results showed that adding PI to saliva during pellicle formation significantly improved erosion protection, as indicated by increased surface microhardness, higher surface reflection intensity, and reduced calcium release. Exchanging saliva also had a protective effect, although less significant than the addition of PI. Further research is needed to determine whether these formed pellicles resemble in vivo pellicles more closely.
SCIENTIFIC REPORTS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Constanza E. Fernandez, Ting L. Luo, Carlos Gonzalez-Cabezas, Alexander H. Rickard
Summary: The study found that unsweetened black tea had significant antimicrobial activity against oral biofilm, while the addition of sugar to tea did not significantly affect its ability to alter biofilm architecture. Furthermore, differences were observed in the effects of green tea and black tea on biofilm, indicating varying impacts of the two types of tea.
ARCHIVES OF ORAL BIOLOGY
(2022)
Article
Biophysics
Marwa Bawazir, Atul Dhall, Jeewoo Lee, Brett Kim, Geelsu Hwang
Summary: Biofilms are difficult to eradicate or kill once formed, so targeting the initial stage of biofilm formation, the microbial adhesion process, is a reasonable approach. The effect of surface stiffness on bacterial adhesion has been relatively underexplored, thus this study aimed to investigate this effect using representative oral bacteria and fungus. The findings provide new insights into microbial mechanosensing and adhesion behavior, which may be useful for future anti-adhesion strategies.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Immunology
Katsunori Kohda, Xuan Li, Naoki Soga, Risa Nagura, Tie Duerna, Saeko Nakajima, Ichiro Nakagawa, Masakazu Ito, Akinori Ikeuchi
Summary: The study established a mixed infection model in a 3D human epidermal model, incorporating both commensal (Staphylococcus epidermidis) and pathogenic (Staphylococcus aureus) bacteria. It was observed that co-infecting the 3D epidermal model with S. aureus and S. epidermidis restricted the growth of S. aureus and elicited protective effects on the integrity of the epidermal barrier. This 3D culture-based mixed infection model could serve as an effective alternative to traditional animal models and 2D cell culture approaches for studying skin health.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Min Young Kim, In Kyung Hyun, Sunghyun An, Donghan Kim, Ki Hwan Kim, Seok-Seong Kang
Summary: This study found that BLs extracted from Lactobacillus plantarum and L. rhamnosus GG can suppress periodontal inflammation and interfere with biofilm formation by Streptococcus mutans. BLs regulate the MAPK and NF-kappa B signaling pathways and reduce the synthesis of extracellular polysaccharide, thereby improving oral health.
Article
Materials Science, Biomaterials
Vanessa Jane Banun, Prarthana Rewatkar, Zanib Chaudhary, Zhi Qu, Taskeen Janjua, Anuja Patil, Yuao Wu, Hang T. Ta, Nidhi Bansal, Jared A. Miles, Benjamin P. Ross, Tushar Kumeria, Amirali Popat
Summary: Coenzyme-Q10 (CoQ10) is encapsulated into milk derived protein nanoparticles to enhance its solubility, stability, and bioavailability. These nanoparticles significantly improve the solubility and permeability of CoQ10 by up to 300-fold compared to pure CoQ10. The study also demonstrates that the nanoparticles have a sustained release profile and enhanced antioxidant properties, making them a promising approach for improving oral delivery of poorly soluble drugs and nutraceuticals.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Nursing
Jie Zhang, John A. Duley, David M. Cowley, Paul N. Shaw, Peng Zhou, Pieter Koorts, Nidhi Bansal
Summary: This study aimed to investigate the effects of different heating temperatures on the bioactive components in donor human milk. The results showed that all proteins studied retained over 60% concentrations or activities when heated at 50°C or lower, but were lost at higher temperatures. The concentrations or activities of immune proteins and bioactive enzymes decreased when heated above 50°C.
JOURNAL OF HUMAN LACTATION
(2023)
Article
Engineering, Industrial
Kelly Hinckfuss, Penelope M. Sanderson, Birgit Brecknell, Robert G. Loeb, David Liu, Helen Liley
Summary: Standard pulse oximeter auditory tones do not clearly indicate departures from the target range of oxygen saturation in preterm neonates. Acoustically enhanced tones significantly improve clinicians' and non-clinicians' ability to identify the SpO2 range. The accuracy of range identification was higher in the enhanced conditions compared to the standard condition, with the tremolo-enhanced tones showing the highest accuracy.
APPLIED ERGONOMICS
(2023)
Article
Obstetrics & Gynecology
Poliana de Barros Medeiros, Helen Liley, Christine Andrews, Adrienne Gordon, Alexander E. P. Heazell, Alison L. Kent, Susannah H. Leisher, Vicki Flenady
Summary: Neonatal near-miss (NNM) audit is viewed as a valuable tool to reduce adverse neonatal outcomes. The survey results showed that the main characteristics of NNM according to most participants include birth asphyxia needing therapeutic hypothermia, unexpected resuscitation at birth, need for intubation/chest compression/adrenaline, and metabolic acidosis at birth. Despite the importance of NNM for identifying cases for perinatal morbidity audits, only a few institutions used a NNM definition.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2023)
Article
Food Science & Technology
Elisabeth K. Prabawati, Mark S. Turner, Nidhi Bansal
Summary: Several strains of Lactiplantibacillus plantarum showed antifungal activity and prolonged the shelf life of Cheddar cheese as adjunct cultures.
Article
Neurosciences
Alex M. Pagnozzi, Liza van Eijk, Kerstin Pannek, Roslyn N. Boyd, Susmita Saha, Joanne George, Samudragupta Bora, DanaKai Bradford, Michael Fahey, Michael Ditchfield, Atul Malhotra, Helen Liley, Paul B. Colditz, Stephen Rose, Jurgen Fripp
Summary: Infants born very preterm face neurodevelopmental challenges and early identification through clinical assessment and MRI can enable targeted interventions. This study used a prospective cohort of preterm infants and identified early MRI biomarkers for neurodevelopmental outcomes using advanced imaging techniques. The results demonstrated the utility of MRI prior to term equivalent age for predicting outcomes and initiating early interventions.
Review
Biology
Farzan Zare, Negareh Ghasemi, Nidhi Bansal, Hamid Hosano
Summary: There is a need for alternative technologies to provide safe and nutritious foods at lower costs. Pulsed electric field (PEF) technology has diverse applications in the life and physical sciences. Its application in liquid foods presents challenges such as food safety targets, maintaining quality, and industrial scale-up. This study discusses the engineering principles, microorganism inactivation models, and theories to enhance the quality and safety of various liquid foods.
PHYSICS OF LIFE REVIEWS
(2023)
Article
Food Science & Technology
Thao M. Ho, Andre Tanzil, Bhesh R. Bhandari, Nidhi Bansal
Summary: The presence of low molecular weight surfactants can interfere with milk proteins, leading to poor foam stability. This study investigated the effects of various surfactants on the foaming properties of reconstituted skim milk powders. Different surfactants with varying charges and molecular weights were tested, and their impact on foamability, foam stability, and structure was evaluated. The results showed that different surfactants had different effects on milk properties, leading to changes in foam behavior. Some surfactants decreased milk foamability, while others induced the production of large air bubbles in the foam, negatively impacting foam stability.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Chemistry, Applied
Jie Zhang, Negareh Ghasemi, Firuz Zare, John A. Duley, David M. Cowley, Paul N. Shaw, Pieter Koorts, Nidhi Bansal
Summary: In this study, nanosecond pulsed electric fields (nsPEF) were used to optimize the processing conditions of donor human milk to reduce bacterial counts and evaluate its effect on bioactive proteins. Response surface methodology was used to optimize critical processing parameters, and two optimal nsPEF processing conditions were validated. The results showed that nsPEF processed milk had high retention rates of various important proteins and had lower protein loss compared to Holder pasteurization. This study suggests that nsPEF is a promising novel pasteurization method.
Article
Chemistry, Applied
Jie Zhang, John A. Duley, David M. Cowley, Paul N. Shaw, Pieter Koorts, Nidhi Bansal
Summary: This study compared the effects of Holder pasteurization (HoP) and hydrostatic high-pressure (HHP) processing on human milk proteins. The results showed that HHP processing better preserved the protein profile of human milk compared to HoP.
Article
Agriculture, Multidisciplinary
Thao M. Ho, Bhesh R. Bhandari, Nidhi Bansal
Summary: This study investigated the foaming properties and foam structure of milk samples induced with lipolysis by different methods. The results showed that milk samples induced by microfluidisation had the highest foamability and foam stability, with small and homogeneous air bubbles. Increasing FFA content from 1.5 to 3.5μ-equiv.mL(-1) significantly decreased the surface tension, foamability, and foam stability of milk samples. The lipolysis induced by microfluidisation had less detrimental effects on the foaming properties of milk compared to ultra-turraxing and homogenisation-induced lipolysis.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Food Science & Technology
Xiaoying Xiong, Eeshaan Pundalik, Vassilis Kontogiorgos, Minh Thao Ho, Chuanzi Mo, Bhesh Bhandari, Nidhi Bansal
Summary: A comprehensive study was conducted to investigate the effect of mineral content on milk foaming properties. Different mineral types showed different effects on the physicochemical properties of milk samples. The addition of CaCl2 or MgCl2 increased foam strength and stability but decreased foamability, while the addition of K3Cit had the opposite effect.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Agriculture, Multidisciplinary
Thao M. Ho, Bhesh R. Bhandari, Nidhi Bansal
Summary: The reasons for the poor foaming quality of milk in summer are still unknown. This study collected milk samples from different processing stages in a dairy factory during two seasons and found that the composition and physical properties of milk in summer were different from those in spring, which may be the reason for its poor foamability.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Review
Critical Care Medicine
V. V. Ramaswamy, J. A. Dawson, M. F. de Almeida, D. Trevisanuto, F. L. Nakwa, C. O. F. Kamlin, J. Trang, M. H. Wyckoff, G. M. Weiner, H. G. Liley
Summary: This study evaluated delivery room interventions to prevent hypothermia and improve outcomes in preterm newborn infants. The findings suggest that increasing the delivery room temperature, using a radiant warmer in manual mode, using a plastic bag or wrap, and covering the head can improve temperature outcomes in preterm infants. However, some interventions may also increase the risk of hyperthermia.
Review
Pediatrics
P. B. Medeiros, C. Bailey, D. Pollock, H. Liley, A. Gordon, C. Andrews, V. Flenady
Summary: This review evaluates the effectiveness of neonatal near-miss (NNM) audits for reducing perinatal mortality and morbidity and explores related contextual factors. The available data on NNM audits are limited, and further research is needed to determine their effectiveness and influencing factors.