Humanization of Antibodies using a Statistical Inference Approach

Antibody humanization by molecular dynamics simulations-in-silicoguided selection of critical backmutations

(2016) Christian Margreitter et al.   JOURNAL OF MOLECULAR RECOGNITION

Maximum-Entropy Models of Sequenced Immune Repertoires Predict Antigen-Antibody Affinity

(2016) Lorenzo Asti et al.   PLoS Computational Biology

A humanized anti-DLL4 antibody promotes dysfunctional angiogenesis and inhibits breast tumor growth

(2016) Xuelian Jia et al.   Scientific Reports

ANARCI: antigen receptor numbering and receptor classification

(2015) James Dunbar et al.   BIOINFORMATICS

Antibody humanization by structure-based computational protein design

(2015) Yoonjoo Choi et al.   mAbs

Humanized antibody neutralizing 2009 pandemic H1N1 virus

(2014) Nachiket Shembekar et al.   Biotechnology Journal

Discovery and characterization of olokizumab

(2014) Stevan Shaw et al.   mAbs

Fast and Accurate Multivariate Gaussian Modeling of Protein Families: Predicting Residue Contacts and Protein-Interaction Partners

(2014) Carlo Baldassi et al.   PLoS One

Monoclonal antibody humanness score and its applications

(2013) Sean H Gao et al.   BMC BIOTECHNOLOGY

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

Development of Scoring Functions for Antibody Sequence Assessment and Optimization

(2013) Daniel Seeliger   PLoS One

The Structural Basis of Antibody-Antigen Recognition

(2013) Inbal Sela-Culang et al.   Frontiers in Immunology

Humanization and Characterization of an Anti-Ricin Neutralization Monoclonal Antibody

(2012) Wei-Gang Hu et al.   PLoS One

Construction and humanization of a functional bispecific EGFR × CD16 diabody using a refolding system

(2011) Ryutaro Asano et al.   FEBS Journal

A database of immunoglobulins with integrated tools: DIGIT

(2011) A. Chailyan et al.   NUCLEIC ACIDS RESEARCH

Direct-coupling analysis of residue coevolution captures native contacts across many protein families

(2011) F. Morcos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The immunogenicity of humanized and fully human antibodies

(2010) Fiona A. Harding et al.   mAbs

Reducing risk, improving outcomes: Bioengineering less immunogenic protein therapeutics

(2009) Anne S. De Groot et al.   CLINICAL IMMUNOLOGY

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

A humanized anti-M2 scFv shows protective in vitro activity against influenza

(2008) J. Gabbard et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach

(2008) Peng Wang et al.   PLoS Computational Biology