A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage

Mechanobiological modeling of endochondral ossification: an experimental and computational analysis

(2018) J. J. Vaca-González et al.   Biomechanics and Modeling in Mechanobiology

Local and global measurements show that damage initiation in articular cartilage is inhibited by the surface layer and has significant rate dependence

(2018) Lena R. Bartell et al.   JOURNAL OF BIOMECHANICS

Mapping the spatiotemporal evolution of solute transport in articular cartilage explants reveals how cartilage recovers fluid within the contact area during sliding

(2018) Brian T. Graham et al.   JOURNAL OF BIOMECHANICS

Inflammatory and degenerative phases resulting from anterior cruciate rupture in a non-invasive murine model of post-traumatic osteoarthritis

(2018) Sophie Jane Gilbert et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effect of frequency on crack growth in articular cartilage

(2018) H. Sadeghi et al.   Journal of the Mechanical Behavior of Biomedical Materials

Mechanical viability of a thermoplastic elastomer hydrogel as a soft tissue replacement material

(2018) Kristine M. Fischenich et al.   Journal of the Mechanical Behavior of Biomedical Materials

Dynamical heterogeneities and mechanical non-linearities: Modeling the onset of plasticity in polymer in the glass transition

(2017) R. J. Masurel et al.   EUROPEAN PHYSICAL JOURNAL E

Multiscale Strain as a Predictor of Impact-Induced Fissuring in Articular Cartilage

(2017) Corinne R. Henak et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

On mechanical mechanism of damage evolution in articular cartilage

(2017) Yu-tao Men et al.   Materials Science & Engineering C-Materials for Biological Applications

Flow velocity-driven differentiation of human mesenchymal stromal cells in silk fibroin scaffolds: A combined experimental and computational approach

(2017) Jolanda Rita Vetsch et al.   PLoS One

Age-Dependent Subchondral Bone Remodeling and Cartilage Repair in a Minipig Defect Model

(2017) Christian G. Pfeifer et al.   TISSUE ENGINEERING PART C-METHODS

Experimental Study on the Mechanical Properties of Porcine Cartilage with Microdefect under Rolling Load

(2017) Yu-tao Men et al.   Journal of Healthcare Engineering

Modeling IL-1 induced degradation of articular cartilage

(2016) Saptarshi Kar et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The effect of loading rate on the development of early damage in articular cartilage

(2016) J. M. Párraga Quiroga et al.   Biomechanics and Modeling in Mechanobiology

An evolutionary model of osteoarthritis including articular cartilage damage, and bone remodeling in a computational study

(2016) Michael E. Stender et al.   JOURNAL OF BIOMECHANICS

Spatial variation of fixed charge density in knee joint cartilage from sodium MRI – Implication on knee joint mechanics under static loading

(2016) Lasse P. Räsänen et al.   JOURNAL OF BIOMECHANICS

Site-specific cell-tissue interactions in rabbit knee joint articular cartilage

(2016) A.P. Ronkainen et al.   JOURNAL OF BIOMECHANICS

A comparison of stress in cracked fibrous tissue specimens with varied crack location, loading, and orientation using finite element analysis

(2016) John M. Peloquin et al.   Journal of the Mechanical Behavior of Biomedical Materials

Influence of different mechanical stimuli in a multi-scale mechanobiological isotropic model for bone remodelling

(2016) E.G.F. Mercuri et al.   MEDICAL ENGINEERING & PHYSICS

Systems Based Study of the Therapeutic Potential of Small Charged Molecules for the Inhibition of IL-1 Mediated Cartilage Degradation

(2016) Saptarshi Kar et al.   PLoS One

Development of a Cartilage Shear-Damage Model to Investigate the Impact of Surface Injury on Chondrocytes and Extracellular Matrix Wear

(2016) Robert L. Trevino et al.   Cartilage

A Novel Method to Simulate the Progression of Collagen Degeneration of Cartilage in the Knee: Data from the Osteoarthritis Initiative

(2016) Mika E. Mononen et al.   Scientific Reports

Quantitative Evaluation of the Mechanical Risks Caused by Focal Cartilage Defects in the Knee

(2016) Mikko S. Venäläinen et al.   Scientific Reports

Knee pain, knee injury, knee osteoarthritis & work

(2015) Gurdeep S. Dulay et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Poroelastic analysis of interstitial fluid flow in a single lamellar trabecula subjected to cyclic loading

(2015) Yoshitaka Kameo et al.   Biomechanics and Modeling in Mechanobiology

An Equilibrium Constitutive Model of Anisotropic Cartilage Damage to Elucidate Mechanisms of Damage Initiation and Progression

(2015) Michael E. Stender et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Site-dependent biomechanical responses of chondrocytes in the rabbit knee joint

(2015) J.M. Fick et al.   JOURNAL OF BIOMECHANICS

Measuring microscale strain fields in articular cartilage during rapid impact reveals thresholds for chondrocyte death and a protective role for the superficial layer

(2015) Lena R. Bartell et al.   JOURNAL OF BIOMECHANICS

Very early osteoarthritis changes sensitively fluid flow properties of articular cartilage

(2015) J.T.A Mäkelä et al.   JOURNAL OF BIOMECHANICS

Structure-Function Relations and Rigidity Percolation in the Shear Properties of Articular Cartilage

(2014) Jesse L. Silverberg et al.   BIOPHYSICAL JOURNAL

Cartilage collagen damage in hip osteoarthritis similar to that seen in knee osteoarthritis; a case–control study of relationship between collagen, glycosaminoglycan and cartilage swelling

(2013) Shahrzad Hosseininia et al.   BMC MUSCULOSKELETAL DISORDERS

Moderate dynamic compression inhibits pro-catabolic response of cartilage to mechanical injury, tumor necrosis factor-α and interleukin-6, but accentuates degradation above a strain threshold

(2013) Y. Li et al.   OSTEOARTHRITIS AND CARTILAGE

A numerical model to study mechanically induced initiation and progression of damage in articular cartilage

(2013) S.M. Hosseini et al.   OSTEOARTHRITIS AND CARTILAGE

Structure–function relationships in osteoarthritic human hip joint articular cartilage

(2012) J.T.A. Mäkelä et al.   OSTEOARTHRITIS AND CARTILAGE

Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis

(2012) B.A. Christiansen et al.   OSTEOARTHRITIS AND CARTILAGE

Is collagen fiber damage the cause of early softening in articular cartilage?

(2012) S.M. Hosseini et al.   OSTEOARTHRITIS AND CARTILAGE

Insights into interstitial flow, shear stress, and mass transport effects on ECM heterogeneity in bioreactor-cultivated engineered cartilage hydrogels

(2011) Tony Chen et al.   Biomechanics and Modeling in Mechanobiology

Contribution of Proteoglycan Osmotic Swelling Pressure to the Compressive Properties of Articular Cartilage

(2011) EunHee Han et al.   BIOPHYSICAL JOURNAL

Post-traumatic osteoarthritis: Improved understanding and opportunities for early intervention

(2011) Donald D. Anderson et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Vulnerability of the superficial zone of immature articular cartilage to compressive injury

(2010) Bernd Rolauffs et al.   ARTHRITIS AND RHEUMATISM

Specificity of Fourier Transform Infrared (FTIR) Microspectroscopy to Estimate Depth-Wise Proteoglycan Content in Normal and Osteoarthritic Human Articular Cartilage

(2010) Simo Saarakkala et al.   Cartilage

N-Acetylcysteine Inhibits Post-Impact Chondrocyte Death in Osteochondral Explants

(2009) James A Martin et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Mechanical Injury and Cytokines Cause Loss of Cartilage Integrity and Upregulate Proteins Associated with Catabolism, Immunity, Inflammation, and Repair

(2009) Anna L. Stevens et al.   MOLECULAR & CELLULAR PROTEOMICS

Importance of Collagen Orientation and Depth-Dependent Fixed Charge Densities of Cartilage on Mechanical Behavior of Chondrocytes

(2008) Rami K. Korhonen et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Indentation diagnostics of cartilage degeneration

(2008) P. Kiviranta et al.   OSTEOARTHRITIS AND CARTILAGE