Engineered Human Contractile Myofiber Sheets as a Platform for Studies of Skeletal Muscle Physiology

Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation

(2017) Cassandra L. Happe et al.   MOLECULAR BIOLOGY OF THE CELL

Experimental study of tuberculosis: From animal models to complex cell systems and organoids

(2017) Kaori L. Fonseca et al.   PLoS Pathogens

In vitro cardiac tissue models: Current status and future prospects

(2016) Anurag Mathur et al.   ADVANCED DRUG DELIVERY REVIEWS

Anisotropic Materials for Skeletal-Muscle-Tissue Engineering

(2016) Soumen Jana et al.   ADVANCED MATERIALS

Three-dimensional cell culture model utilization in cancer stem cell research

(2016) Zofia F. Bielecka et al.   BIOLOGICAL REVIEWS

Striated muscle function, regeneration, and repair

(2016) I. Y. Shadrin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Physiologically relevant human tissue models for infectious diseases

(2016) Melody Mills et al.   DRUG DISCOVERY TODAY

Engineered miniaturized models of musculoskeletal diseases

(2016) Simone Bersini et al.   DRUG DISCOVERY TODAY

Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery

(2016) Alec S.T. Smith et al.   DRUG DISCOVERY TODAY

A human in vitro model of Duchenne muscular dystrophy muscle formation and contractility

(2016) Alexander P. Nesmith et al.   JOURNAL OF CELL BIOLOGY

Induced pluripotent stem cell technology: a decade of progress

(2016) Yanhong Shi et al.   NATURE REVIEWS DRUG DISCOVERY

A Novel Protocol for Directed Differentiation of C9orf72-Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes

(2016) Elliot W. Swartz et al.   Stem Cells Translational Medicine

Recent policies that support clinical application of induced pluripotent stem cell-based regenerative therapies

(2016) Kentaro Azuma et al.   Regenerative Therapy

Improved contractile force generation of tissue-engineered skeletal muscle constructs by IGF-I and Bcl-2 gene transfer with electrical pulse stimulation

(2016) Kazushi Ikeda et al.   Regenerative Therapy

Biomaterials based strategies for skeletal muscle tissue engineering: Existing technologies and future trends

(2015) Taimoor H. Qazi et al.   BIOMATERIALS

Functional myotube formation from adult rat satellite cells in a defined serum-free system

(2015) Christopher W. McAleer et al.   BIOTECHNOLOGY PROGRESS

Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise

(2015) Svenia Schnyder et al.   BONE

Organs from the lab

(2015) Vivien Marx   NATURE

Sarcopenia and diabetes: Hyperglycemia is a risk factor for age-associated muscle mass and functional reduction

(2015) Hiroyuki Umegaki   Journal of Diabetes Investigation

Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells

(2015) Emi Shoji et al.   Scientific Reports

Cell Sheet-Based Tissue Engineering for Organizing Anisotropic Tissue Constructs Produced Using Microfabricated Thermoresponsive Substrates

(2015) Hironobu Takahashi et al.   Advanced Healthcare Materials

Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

(2015) Lauran Madden et al.   eLife

Biomechanical strain vehicles for fibroblast-directed skeletal myoblast differentiation and myotube functionality in a novel coculture

(2014) Michael R. Hicks et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The myokine decorin is regulated by contraction and involved in muscle hypertrophy

(2014) Timo Kanzleiter et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Roles of adherent myogenic cells and dynamic culture in engineered muscle function and maintenance of satellite cells

(2014) Mark Juhas et al.   BIOMATERIALS

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo

(2014) M. Juhas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases

(2014) Rita Rastogi Kalyani et al.   Lancet Diabetes & Endocrinology

The use of anisotropic cell sheets to control orientation during the self-organization of 3D muscle tissue

(2013) Hironobu Takahashi et al.   BIOMATERIALS

Cell sheet engineering and its application for periodontal regeneration

(2013) Takanori Iwata et al.   Journal of Tissue Engineering and Regenerative Medicine

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

Adhesion strength–based, label-free isolation of human pluripotent stem cells

(2013) Ankur Singh et al.   NATURE METHODS

Skeletal Muscle Tissue Engineering: Methods to Form Skeletal Myotubes and Their Applications

(2013) Serge Ostrovidov et al.   TISSUE ENGINEERING PART B-REVIEWS

In vitro differentiation of functional human skeletal myotubes in a defined system

(2013) Xiufang Guo et al.   Biomaterials Science

Matrigel, but not collagen I, maintains the differentiation capacity of muscle derived cellsin vitro

(2012) S Grefte et al.   Biomedical Materials

Fibroblasts influence muscle progenitor differentiation and alignment in contact independent and dependent manners in organized co-culture devices

(2012) Nikhil Rao et al.   BIOMEDICAL MICRODEVICES

Muscle-Specific Vascular Endothelial Growth Factor Deletion Induces Muscle Capillary Rarefaction Creating Muscle Insulin Resistance

(2012) J. S. Bonner et al.   DIABETES

Mechanical strain applied to human fibroblasts differentially regulates skeletal myoblast differentiation

(2012) Michael R. Hicks et al.   JOURNAL OF APPLIED PHYSIOLOGY

Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro

(2012) Yuji Haraguchi et al.   Nature Protocols

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells

(2012) N. Egawa et al.   Science Translational Medicine

Micropatterned Thermoresponsive Polymer Brush Surfaces for Fabricating Cell Sheets with Well-Controlled Orientational Structures

(2011) Hironobu Takahashi et al.   BIOMACROMOLECULES

Anisotropic cell sheets for constructing three-dimensional tissue with well-organized cell orientation

(2011) Hironobu Takahashi et al.   BIOMATERIALS

Tissue-Engineered Cardiac Constructs for Cardiac Repair

(2010) Shigeru Miyagawa et al.   ANNALS OF THORACIC SURGERY

Interleukin 6 as a Key Regulator of Muscle Mass during Cachexia

(2010) James A. Carson et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Fabrication of a thermoresponsive cell culture dish: a key technology for cell sheet tissue engineering

(2010) Jun Kobayashi et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Effect of VEGF on the Regenerative Capacity of Muscle Stem Cells in Dystrophic Skeletal Muscle

(2009) Bridget M Deasy et al.   MOLECULAR THERAPY

The influence of electrospun aligned poly(ɛ-caprolactone)/collagen nanofiber meshes on the formation of self-aligned skeletal muscle myotubes

(2008) Jin San Choi et al.   BIOMATERIALS

Engineered skeletal muscle tissue networks with controllable architecture

(2008) Weining Bian et al.   BIOMATERIALS

Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs

(2008) Mai T. Lam et al.   BIOMATERIALS

Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers

(2008) I-Chien Liao et al.   Cellular and Molecular Bioengineering

Drug-screening platform based on the contractility of tissue-engineered muscle

(2008) Herman Vandenburgh et al.   MUSCLE & NERVE