MiR-99b-5p and miR-203a-3p Function as Tumor Suppressors by Targeting IGF-1R in Gastric Cancer

Inhibiting IGF-1R attenuates cell proliferation and VEGF production in IGF-1R over-expressing EGFR mutant non-small cell lung cancer cells

(2017) Chang Dong Yeo et al.   EXPERIMENTAL LUNG RESEARCH

SUMO-modified insulin-like growth factor 1 receptor (IGF-1R) increases cell cycle progression and cell proliferation

(2017) Yingbo Lin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†

(2016) E. C. Smyth et al.   ANNALS OF ONCOLOGY

MicroRNA-122 confers sorafenib resistance to hepatocellular carcinoma cells by targeting IGF-1R to regulate RAS/RAF/ERK signaling pathways

(2016) Yanmin Xu et al.   CANCER LETTERS

In vivo delivery of miRNAs for cancer therapy: Challenges and strategies

(2015) Yunching Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells

(2015) KANG HE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Lin28b Promotes Head and Neck Cancer Progression via Modulation of the Insulin-Like Growth Factor Survival Pathway

(2015) Nehad M Alajez et al.   Oncotarget

miR-203a regulates proliferation, migration, and apoptosis by targeting glycogen synthase kinase-3β in human renal cell carcinoma

(2014) Guanghui Hu et al.   TUMOR BIOLOGY

Long-term outcomes of endoscopic submucosal dissection for early gastric cancer: A single-center retrospective study

(2013) Takashi Kosaka et al.   Digestive Endoscopy

miR-338-3p Suppresses Gastric Cancer Progression through a PTEN-AKT Axis by Targeting P-REX2a

(2013) Bo Guo et al.   MOLECULAR CANCER RESEARCH

Upregulation of miR-150* and miR-630 Induces Apoptosis in Pancreatic Cancer Cells by Targeting IGF-1R

(2013) Lulu Farhana et al.   PLoS One

miR-294/miR-302 Promotes Proliferation, Suppresses G1-S Restriction Point, and Inhibits ESC Differentiation through Separable Mechanisms

(2013) Yangming Wang et al.   Cell Reports

MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

(2012) Tilanthi M. Jayawardena et al.   CIRCULATION RESEARCH

Delivering the promise of miRNA cancer therapeutics

(2012) Diane M. Pereira et al.   DRUG DISCOVERY TODAY

MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

(2012) Marilena V. Iorio et al.   EMBO Molecular Medicine

MIR-99a and MIR-99b Modulate TGF-β Induced Epithelial to Mesenchymal Plasticity in Normal Murine Mammary Gland Cells

(2012) Gianluca Turcatel et al.   PLoS One

The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer

(2011) Ching-yi Chang et al.   CANCER CELL

Light at Night Activates IGF-1R/PDK1 Signaling and Accelerates Tumor Growth in Human Breast Cancer Xenografts

(2011) J. Wu et al.   CANCER RESEARCH

A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

(2011) Kim J. Png et al.   NATURE

MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis

(2011) Qing Xu et al.   NUCLEIC ACIDS RESEARCH

Clinicopathological and Prognostic Value of MicroRNA-21 and MicroRNA-155 in Colorectal Cancer

(2011) Hajime Shibuya et al.   ONCOLOGY

MicroRNA-126 Inhibits SOX2 Expression and Contributes to Gastric Carcinogenesis

(2011) Takeshi Otsubo et al.   PLoS One

Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K

(2010) Jessie Villanueva et al.   CANCER CELL

Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

(2010) D. B. Ulanet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types

(2009) Richard Hummel et al.   EUROPEAN JOURNAL OF CANCER

MicroRNAs in Cancer: Small Molecules With a Huge Impact

(2009) Marilena V. Iorio et al.   JOURNAL OF CLINICAL ONCOLOGY

Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells

(2008) Richard J. Santen et al.   STEROIDS