Establishing normal metabolism and differentiation in hepatocellular carcinoma cells by culturing in adult human serum

Use of a neonatal rat system as a bioincubator to generate adult-like mature cardiomyocytes from human and mouse pluripotent stem cells

(2017) Gun-Sik Cho et al.   Nature Protocols

Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras

(2017) Ken Peeters et al.   Nature Communications

Culturing of HepG2 cells with human serum improve their functionality and suitability in studies of lipid metabolism

(2016) Camilla Pramfalk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

The use of human umbilical cord blood serum is beneficial for the continuous production of hepatitis C virus

(2016) Xiao-Yang Jiao et al.   JOURNAL OF GENERAL VIROLOGY

Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver

(2016) Michael E. Fusakio et al.   MOLECULAR BIOLOGY OF THE CELL

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Initial characterization of Vaccinia Virus B4 suggests a role in virus spread

(2014) Kristin Burles et al.   VIROLOGY

Human serum activates CIDEB-mediated lipid droplet enlargement in hepatoma cells

(2013) Ragunath Singaravelu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers

(2013) Rineke H.G. Steenbergen et al.   HEPATOLOGY

A community-driven global reconstruction of human metabolism

(2013) Ines Thiele et al.   NATURE BIOTECHNOLOGY

Insulin and igfs enhance hepatocyte differentiation from human embryonic stem cells via the PI3K/AKT pathway

(2013) Nataly L. Magner et al.   STEM CELLS

Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice

(2013) Anwar Anwar-Mohamed et al.   XENOBIOTICA

DREM 2.0: Improved reconstruction of dynamic regulatory networks from time-series expression data

(2012) Marcel H Schulz et al.   BMC Systems Biology

A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC–MS/MS

(2012) Venkateswaran C. Pillai et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IGFBP3 impedes aggressive growth of pediatric liver cancer and is epigenetically silenced in vascular invasive and metastatic tumors

(2012) Ivonne Regel et al.   Molecular Cancer

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Insulin-like growth factor 1 (IGF-I) improves hepatic differentiation of human bone marrow-derived mesenchymal stem cells

(2011) Maryam Ayatollahi et al.   CELL BIOLOGY INTERNATIONAL

Early Growth Response 1 (Egr1) Regulates Cholesterol Biosynthetic Gene Expression

(2011) Nolan G. Gokey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relevance of the MEK/ERK Signaling Pathway in the Metabolism of Activated Macrophages: A Metabolomic Approach

(2011) P. G. Traves et al.   JOURNAL OF IMMUNOLOGY

Functional integration of a metabolic network model and expression data without arbitrary thresholding

(2010) Paul A. Jensen et al.   BIOINFORMATICS

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

The Aryl Hydrocarbon Receptor Functions as a Tumor Suppressor of Liver Carcinogenesis

(2009) Y. Fan et al.   CANCER RESEARCH

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Endogenous Functions of the Aryl Hydrocarbon Receptor (AHR): Intersection of Cytochrome P450 1 (CYP1)-metabolized Eicosanoids and AHR Biology

(2008) Daniel W. Nebert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria in cancer: Not just innocent bystanders

(2008) Christian Frezza et al.   SEMINARS IN CANCER BIOLOGY