A platform for efficient identification of molecular phenotypes of brain-wide neural circuits

Mapping of Brain Activity by Automated Volume Analysis of Immediate Early Genes

(2016) Nicolas Renier et al.   CELL

Clearing of fixed tissue: a review from a microscopist’s perspective

(2016) Ludovico Silvestri et al.   JOURNAL OF BIOMEDICAL OPTICS

Selectivity of Neuromodulatory Projections from the Basal Forebrain and Locus Ceruleus to Primary Sensory Cortices

(2016) Jae-Hyun Kim et al.   JOURNAL OF NEUROSCIENCE

Shrinkage-mediated imaging of entire organs and organisms using uDISCO

(2016) Chenchen Pan et al.   NATURE METHODS

Organization of long-range inputs and outputs of frontal cortex for top-down control

(2016) Siyu Zhang et al.   NATURE NEUROSCIENCE

Basal Forebrain Cholinergic Circuits and Signaling in Cognition and Cognitive Decline

(2016) Elizabeth C. Ballinger et al.   NEURON

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

(2016) D. Gowanlock R. Tervo et al.   NEURON

A platform for brain-wide imaging and reconstruction of individual neurons

(2016) Michael N Economo et al.   eLife

Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems

(2015) Evan Murray et al.   CELL

Clarifying Tissue Clearing

(2015) Douglas S. Richardson et al.   CELL

Organization of the Locus Coeruleus-Norepinephrine System

(2015) Lindsay A. Schwarz et al.   CURRENT BIOLOGY

Viral-genetic tracing of the input–output organization of a central noradrenaline circuit

(2015) Lindsay A. Schwarz et al.   NATURE

ScaleS: an optical clearing palette for biological imaging

(2015) Hiroshi Hama et al.   NATURE NEUROSCIENCE

Three Types of Cortical Layer 5 Neurons That Differ in Brain-wide Connectivity and Function

(2015) Euiseok J. Kim et al.   NEURON

Visualizing Whole-Brain Activity and Development at the Single-Cell Level Using Light-Sheet Microscopy

(2015) Philipp J. Keller et al.   NEURON

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

(2014) Etsuo A. Susaki et al.   CELL

Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

(2014) Bin Yang et al.   CELL

iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

Neural Networks of the Mouse Neocortex

(2014) Brian Zingg et al.   CELL

A mesoscale connectome of the mouse brain

(2014) Seung Wook Oh et al.   NATURE

A comprehensive thalamocortical projection map at the mesoscopic level

(2014) Barbara J Hunnicutt et al.   NATURE NEUROSCIENCE

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

(2014) Raju Tomer et al.   Nature Protocols

Long-range connectomics

(2013) Saad Jbabdi et al.   Annals of the New York Academy of Sciences

Fast optical sectioning obtained by structured illumination microscopy using a digital mirror device

(2013) Dongli Xu et al.   JOURNAL OF BIOMEDICAL OPTICS

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

Continuously tracing brain-wide long-distance axonal projections in mice at a one-micron voxel resolution

(2013) Hui Gong et al.   NEUROIMAGE

Serial two-photon tomography for automated ex vivo mouse brain imaging

(2012) Timothy Ragan et al.   NATURE METHODS

Orienting and Reorienting: The Locus Coeruleus Mediates Cognition through Arousal

(2012) Susan J. Sara et al.   NEURON

Confocal light sheet microscopy: micron-scale neuroanatomy of the entire mouse brain

(2012) L. Silvestri et al.   OPTICS EXPRESS

Cortical representations of olfactory input by trans-synaptic tracing

(2010) Kazunari Miyamichi et al.   NATURE

Image contrast enhancement in confocal ultramicroscopy

(2010) Stefan Kalchmair et al.   OPTICS LETTERS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE