The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells

Hsp90 Inhibitors NVP-AUY922 and NVP-BEP800 May Exert a Significant Radiosensitization on Tumor Cells along with a Cell Type-Specific Cytotoxicity

(2014) Natalia Niewidok et al.   Translational Oncology

Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells

(2013) Nishant Gandhi et al.   CANCER BIOLOGY & THERAPY

The HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin modulates radiosensitivity by downregulating serine/threonine kinase 38 via Sp1 inhibition

(2013) Atsushi Enomoto et al.   EUROPEAN JOURNAL OF CANCER

Hsp90, an unlikely ally in the war on cancer

(2013) Jared J. Barrott et al.   FEBS Journal

Combining Heavy Ion Radiation and Artificial MicroRNAs to Target the Homologous Recombination Repair Gene Efficiently Kills Human Tumor Cells

(2013) Zhiming Zheng et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Inhibition of HSP90 molecular chaperones: moving into the clinic

(2013) Rocio Garcia-Carbonero et al.   LANCET ONCOLOGY

Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990

(2013) Dušan Milanović et al.   Radiation Oncology

Hsp90 inhibitor NVP-AUY922 enhances radiation sensitivity of tumor cell lines under hypoxia

(2012) Cholpon S. Djuzenova et al.   CANCER BIOLOGY & THERAPY

Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?

(2012) L. Neckers et al.   CLINICAL CANCER RESEARCH

Radiosensitization of Normoxic and Hypoxic H1339 Lung Tumor Cells by Heat Shock Protein 90 Inhibition Is Independent of Hypoxia Inducible Factor-1α

(2012) Daniela Schilling et al.   PLoS One

The HSP90 Inhibitor NVP-AUY922 Radiosensitizes by Abrogation of Homologous Recombination Resulting in Mitotic Entry with Unresolved DNA Damage

(2012) Shane Zaidi et al.   PLoS One

BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation

(2012) S. R. Stecklein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers

(2011) Komal Jhaveri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effects of Carbon Ion Beam on Putative Colon Cancer Stem Cells and Its Comparison with X-rays

(2011) X. Cui et al.   CANCER RESEARCH

Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment

(2011) Hardik J Patel et al.   Expert Opinion on Drug Discovery

Repair of DNA damage induced by accelerated heavy ions-A mini review

(2011) Ryuichi Okayasu   INTERNATIONAL JOURNAL OF CANCER

Hsp90 Inhibitor-Mediated Disruption of Chaperone Association of ATR with Hsp90 Sensitizes Cancer Cells to DNA Damage

(2011) K. Ha et al.   MOLECULAR CANCER THERAPEUTICS

Heavy charged particle radiobiology: Using enhanced biological effectiveness and improved beam focusing to advance cancer therapy

(2011) Christopher Allen et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction

(2010) L Stingl et al.   BRITISH JOURNAL OF CANCER

Carbon Ion Radiotherapy: Clinical Experiences at National Institute of Radiological Science (NIRS)

(2010) Tohru OKADA et al.   JOURNAL OF RADIATION RESEARCH

Recent Advances in the Biology of Heavy-Ion Cancer Therapy

(2010) Nobuyuki HAMADA et al.   JOURNAL OF RADIATION RESEARCH

Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation

(2010) H. Wang et al.   NUCLEIC ACIDS RESEARCH

DNA polymerase β and PARP activities in base excision repair in living cells

(2009) Aya Masaoka et al.   DNA REPAIR

Chemopreventive agent sulforaphane enhances radiosensitivity in human tumor cells

(2009) Dong Yu et al.   INTERNATIONAL JOURNAL OF CANCER

The Ku-dependent non-homologous end-joining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation

(2008) Hongyan Wang et al.   DNA REPAIR

HSP90 inhibitor, DMAG, synergizes with radiation of lung cancer cells by interfering with base excision and ATM-mediated DNA repair

(2008) T. T. Koll et al.   MOLECULAR CANCER THERAPEUTICS