Pediatric phase I trial of oral sorafenib and topotecan in refractory or recurrent pediatric solid malignancies

Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial

(2015) Giovanni Grignani et al.   LANCET ONCOLOGY

EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment†

(2014) J. S. Whelan et al.   ANNALS OF ONCOLOGY

Sorafenib in advanced, heavily pretreated patients with soft tissue sarcomas

(2014) Kira Brämswig et al.   ANTI-CANCER DRUGS

Sorafenib and irinotecan (NEXIRI) as second- or later-line treatment for patients with metastatic colorectal cancer and KRAS-mutated tumours: a multicentre Phase I/II trial

(2014) E Samalin et al.   BRITISH JOURNAL OF CANCER

A Phase I, Dose-Finding Study in Patients with Advanced Solid Malignancies of the Oral  -Secretase Inhibitor PF-03084014

(2014) W. A. Messersmith et al.   CLINICAL CANCER RESEARCH

Final report of phase II study of sorafenib, cytarabine and idarubicin for initial therapy in younger patients with acute myeloid leukemia

(2014) F Ravandi et al.   LEUKEMIA

Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations

(2014) R. A. Gatenby et al.   Nature Communications

A Proposal Regarding Reporting of In Vitro Testing Results

(2013) M. A. Smith et al.   CLINICAL CANCER RESEARCH

The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models

(2013) Y. Pignochino et al.   CLINICAL CANCER RESEARCH

Future of Clinical Genomics in Pediatric Oncology

(2013) Katherine A. Janeway et al.   JOURNAL OF CLINICAL ONCOLOGY

Response to Sorafenib in a Pediatric Patient with Papillary Thyroid Carcinoma with Diffuse Nodular Pulmonary Disease Requiring Mechanical Ventilation

(2013) Pallavi Iyer et al.   THYROID

A Phase I Trial and Pharmacokinetic Study of Sorafenib in Children with Refractory Solid Tumors or Leukemias: A Children's Oncology Group Phase I Consortium Report

(2012) B. C. Widemann et al.   CLINICAL CANCER RESEARCH

Randomized Controlled Trial of Interval-Compressed Chemotherapy for the Treatment of Localized Ewing Sarcoma: A Report From the Children's Oncology Group

(2012) Richard B. Womer et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase I trial and pharmacokinetic study of sorafenib in children with neurofibromatosis type I and plexiform neurofibromas

(2012) AeRang Kim et al.   PEDIATRIC BLOOD & CANCER

Children's Oncology Group's 2013 blueprint for research: Renal tumors

(2012) Jeffrey S. Dome et al.   PEDIATRIC BLOOD & CANCER

A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study

(2011) G. Grignani et al.   ANNALS OF ONCOLOGY

Activity of Sorafenib against Desmoid Tumor/Deep Fibromatosis

(2011) M. M. Gounder et al.   CLINICAL CANCER RESEARCH

Sorafenib in combination with weekly topotecan in recurrent ovarian cancer, a phase I/II study of the Hoosier Oncology Group

(2011) R. Ramasubbaiah et al.   GYNECOLOGIC ONCOLOGY

Phase I Pharmacokinetic and Pharmacodynamic Study of the Multikinase Inhibitor Sorafenib in Combination With Clofarabine and Cytarabine in Pediatric Relapsed/Refractory Leukemia

(2011) Hiroto Inaba et al.   JOURNAL OF CLINICAL ONCOLOGY

Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma

(2010) Alice L. Yu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Initial testing (stage 1) of the multi-targeted kinase inhibitor sorafenib by the pediatric preclinical testing program

(2010) Stephen T. Keir et al.   PEDIATRIC BLOOD & CANCER

Phase II study of topotecan in combination with dexamethasone, asparaginase, and vincristine in pediatric patients with acute lymphoblastic leukemia in first relapse

(2008) Nobuko Hijiya et al.   CANCER

Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

(2008) Scott M. Wilhelm et al.   MOLECULAR CANCER THERAPEUTICS

Development of a rapid and sensitive LC–MS/MS assay for the determination of sorafenib in human plasma

(2007) Lokesh Jain et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS