Human TAUP301L overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain

Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

(2017) Ira Espuny-Camacho et al.   NEURON

A comparative view of regenerative neurogenesis in vertebrates

(2016) Alessandro Alunni et al.   DEVELOPMENT

Expression of A152T human tau causes age‐dependent neuronal dysfunction and loss in transgenic mice

(2016) Sumihiro Maeda et al.   EMBO REPORTS

Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease

(2016) Rosemary J. Jackson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice

(2016) Arne Ittner et al.   SCIENCE

IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain

(2016) Prabesh Bhattarai et al.   Cell Reports

A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions

(2016) Siân Baker et al.   Acta Neuropathologica Communications

HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer’s disease-related tau pathology

(2015) Julia Elisa Sepulveda-Diaz et al.   BRAIN

Effects of inflammation on stem cells: together they strive?

(2015) C. Kizil et al.   EMBO REPORTS

TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

(2015) Taylor R. Jay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Modulation of insulin signaling rescues BDNF transport defects independent of tau in amyloid-β oligomer-treated hippocampal neurons

(2015) Oliver Takach et al.   NEUROBIOLOGY OF AGING

Live imaging of adult neural stem cell behavior in the intact and injured zebrafish brain

(2015) J. S. Barbosa et al.   SCIENCE

2A self-cleaving peptide-based multi-gene expression system in the silkworm Bombyx mori

(2015) Yuancheng Wang et al.   Scientific Reports

Regeneration, Plasticity, and Induced Molecular Programs in Adult Zebrafish Brain

(2015) Mehmet Ilyas Cosacak et al.   Biomed Research International

Efficient Cargo Delivery into Adult Brain Tissue Using Short Cell-Penetrating Peptides

(2015) Caghan Kizil et al.   PLoS One

Tau aggregation and its interplay with amyloid-β

(2014) Rebecca M. Nisbet et al.   ACTA NEUROPATHOLOGICA

Simplet/Fam53b is required for Wnt signal transduction by regulating  -catenin nuclear localization

(2014) C. Kizil et al.   DEVELOPMENT

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Neurodegenerative Disorder FTDP-17–Related Tau Intron 10 +16C→T Mutation Increases Tau Exon 10 Splicing and Causes Tauopathy in Transgenic Mice

(2013) Tomohiro Umeda et al.   AMERICAN JOURNAL OF PATHOLOGY

An Unbiased Approach to Identifying Tau Kinases That Phosphorylate Tau at Sites Associated with Alzheimer Disease

(2013) Annalisa Cavallini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sustained Interleukin-1  Overexpression Exacerbates Tau Pathology Despite Reduced Amyloid Burden in an Alzheimer's Mouse Model

(2013) S. Ghosh et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons

(2013) Elisa M. Ramser et al.   MOLECULAR BIOLOGY OF THE CELL

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Neuroinflammation and central nervous system regeneration in vertebrates

(2013) Nikos Kyritsis et al.   TRENDS IN CELL BIOLOGY

Animal Models of Alzheimer Disease

(2013) F. M. LaFerla et al.   Cold Spring Harbor Perspectives in Medicine

Micromanipulation of Gene Expression in the Adult Zebrafish Brain Using Cerebroventricular Microinjection of Morpholino Oligonucleotides

(2013) Caghan Kizil et al.   Jove-Journal of Visualized Experiments

Mouse models of frontotemporal dementia

(2012) Erik D. Roberson   ANNALS OF NEUROLOGY

Regenerative Neurogenesis from Neural Progenitor Cells Requires Injury-Induced Expression of Gata3

(2012) Caghan Kizil et al.   DEVELOPMENTAL CELL

Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways

(2012) Norbert Zilka et al.   Journal of Neuroinflammation

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain

(2012) Caghan Kizil et al.   Neural Development

Acute Inflammation Initiates the Regenerative Response in the Adult Zebrafish Brain

(2012) N. Kyritsis et al.   SCIENCE

Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors

(2011) V. Kroehne et al.   DEVELOPMENT

Regenerative response following stab injury in the adult zebrafish telencephalon

(2011) Martin März et al.   DEVELOPMENTAL DYNAMICS

Adult neurogenesis and brain regeneration in zebrafish

(2011) Caghan Kizil et al.   Developmental Neurobiology

Neuronal regeneration in a zebrafish model of adult brain injury

(2011) N. Kishimoto et al.   Disease Models & Mechanisms

Stab wound injury of the zebrafish telencephalon: A model for comparative analysis of reactive gliosis

(2011) Emily Violette Baumgart et al.   GLIA

Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation

(2011) Jack Reifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subdivisions of the adult zebrafish subpallium by molecular marker analysis

(2011) Julia Ganz et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Cerebroventricular Microinjection (CVMI) into Adult Zebrafish Brain Is an Efficient Misexpression Method for Forebrain Ventricular Cells

(2011) Caghan Kizil et al.   PLoS One

Abnormal Cognition, Sleep, EEG and Brain Metabolism in a Novel Knock-In Alzheimer Mouse, PLB1

(2011) Bettina Platt et al.   PLoS One

Aβ Accelerates the Spatiotemporal Progression of Tau Pathology and Augments Tau Amyloidosis in an Alzheimer Mouse Model

(2010) David E. Hurtado et al.   AMERICAN JOURNAL OF PATHOLOGY

Investigating regeneration and functional integration of CNS neurons: Lessons from zebrafish genetics and other fish species

(2010) Valerie C. Fleisch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish

(2010) C. Mosimann et al.   DEVELOPMENT

Generation of a non-leaky heat shock-inducible Cre line for conditional Cre/lox strategies in zebrafish

(2010) Stefan Hans et al.   DEVELOPMENTAL DYNAMICS

Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice

(2010) Michael Demars et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Transgenic Zebrafish as a Novel Animal Model to Study Tauopathies and Other Neurodegenerative Disorders in vivo

(2010) Dominik Paquet et al.   Neurodegenerative Diseases

Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport: Fig. 1

(2010) Keith A. Vossel et al.   SCIENCE

An Evolutionary Interpretation of Teleostean Forebrain Anatomy

(2009) Thomas Mueller et al.   BRAIN BEHAVIOR AND EVOLUTION

A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation

(2009) Dominik Paquet et al.   JOURNAL OF CLINICAL INVESTIGATION

Stem Cells in the Adult Zebrafish Cerebellum: Initiation and Maintenance of a Novel Stem Cell Niche

(2009) J. Kaslin et al.   JOURNAL OF NEUROSCIENCE

Phosphorylation of Tau at S422 is enhanced by Aβ in TauPS2APP triple transgenic mice

(2009) Fiona Grueninger et al.   NEUROBIOLOGY OF DISEASE

Temporally-Controlled Site-Specific Recombination in Zebrafish

(2009) Stefan Hans et al.   PLoS One

Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo

(2008) Francesca Peri et al.   CELL

Animal models of Alzheimer's disease and frontotemporal dementia

(2008) Jürgen Götz et al.   NATURE REVIEWS NEUROSCIENCE