Interactions of Notch1 and TLR4 signaling pathways in DRG neurons of in vivo and in vitro models of diabetic neuropathy

E6020, a synthetic TLR4 agonist, accelerates myelin debris clearance, Schwann cell infiltration, and remyelination in the rat spinal cord

(2017) Jamie S. Church et al.   GLIA

Toll-like receptor 4 antagonist TAK-242 inhibits autoinflammatory symptoms in DITRA

(2017) Akitaka Shibata et al.   JOURNAL OF AUTOIMMUNITY

Pleiotrophin regulates microglia-mediated neuroinflammation

(2017) Rosalía Fernández-Calle et al.   Journal of Neuroinflammation

Lingo-1 shRNA and Notch signaling inhibitor DAPT promote differentiation of neural stem/progenitor cells into neurons

(2016) Jue Wang et al.   BRAIN RESEARCH

TLR4 and Caveolin-1 in Monocytes Are Associated With Inflammatory Conditions in Diabetic Neuropathy

(2016) T Zhu et al.   CTS-Clinical and Translational Science

Regulation of Notch-mediated transcription by a bovine herpesvirus 1 encoded protein (ORF2) that is expressed in latently infected sensory neurons

(2016) Yilin Liu et al.   JOURNAL OF NEUROVIROLOGY

Viral vector mediated continuous expression of interleukin-10 in DRG alleviates pain in type 1 diabetic animals

(2016) Vikram Thakur et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Toll-like Receptor 4 Mediates Morphine-Induced Neuroinflammation and Tolerance via Soluble Tumor Necrosis Factor Signaling

(2016) Lori N Eidson et al.   NEUROPSYCHOPHARMACOLOGY

Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice

(2016) Tong Liu et al.   PAIN

Synthetic and natural small molecule TLR4 antagonists inhibit motoneuron death in cultures from ALS mouse model

(2016) Massimiliano De Paola et al.   PHARMACOLOGICAL RESEARCH

Iterative Role of Notch Signaling in Spinal Motor Neuron Diversification

(2016) G. Christopher Tan et al.   Cell Reports

Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain

(2016) Niurka Trujillo-Paredes et al.   Biology Open

Role of inflammation in sensory neuropathy in prediabetes or diabetes

(2015) T. Duksal et al.   ACTA NEUROLOGICA SCANDINAVICA

Hes1 and Hes5 are required for differentiation of pituicytes and formation of the neurohypophysis in pituitary development

(2015) Masanori Goto et al.   BRAIN RESEARCH

An in vitro assay to study induction of the regenerative state in sensory neurons

(2015) E. Frey et al.   EXPERIMENTAL NEUROLOGY

Paradoxical effects of VEGF on synaptic activity partially involved in notch1 signaling in the mouse hippocampus

(2015) Jiajia Yang et al.   HIPPOCAMPUS

Membrane receptor-dependent Notch1/Hes1 activation by melatonin protects against myocardial ischemia-reperfusion injury: in vivo and in vitro studies

(2015) Liming Yu et al.   JOURNAL OF PINEAL RESEARCH

Activation of notch signaling mediates the induction and maintenance of mechanical allodynia in a rat model of neuropathic pain

(2015) KELIANG XIE et al.   Molecular Medicine Reports

Identification of a functional interaction of HMGB1 with Receptor for Advanced Glycation End-products in a model of neuropathic pain

(2014) Yohance M. Allette et al.   BRAIN BEHAVIOR AND IMMUNITY

A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord

(2014) Mark D. Borromeo et al.   DEVELOPMENT

Activation of TLR-4 to produce tumour necrosis factor-α in neuropathic pain caused by paclitaxel

(2014) Z. Wu et al.   EUROPEAN JOURNAL OF PAIN

Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord

(2014) Gabriel Rusanescu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The role of TNF-alpha/NF-kappa B pathway on the up-regulation of voltage-gated sodium channel Nav1.7 in DRG neurons of rats with diabetic neuropathy

(2014) Yangliang Huang et al.   NEUROCHEMISTRY INTERNATIONAL

Primary sensory neurons regulate Toll-like receptor-4-dependent activity of glial cells in dorsal root ganglia

(2014) K.-H. Tse et al.   NEUROSCIENCE

The role of TLR4-mediated PTEN/PI3K/AKT/NF-κB signaling pathway in neuroinflammation in hippocampal neurons

(2014) M. Zhao et al.   NEUROSCIENCE

Toll-like receptor 4-mediated nuclear factor-κB activation in spinal cord contributes to chronic morphine-induced analgesic tolerance and hyperalgesia in rats

(2014) Liying Bai et al.   Neuroscience Bulletin

The expression of vesicular glutamate transporter 3 and vesicular monoamine transporter 2 induced by brain-derived neurotrophic factor in dorsal root ganglion neurons in vitro

(2013) Dong Liu et al.   BRAIN RESEARCH BULLETIN

RETRACTED: Increases in inflammatory mediators in DRG implicate in the pathogenesis of painful neuropathy in Type 2 diabetes

(2013) Christina Galloway et al.   CYTOKINE

Streptozotocin-induced diabetic hyperalgesia in rats is associated with upregulation of toll-like receptor 4 expression

(2012) Jian-e Yan et al.   NEUROSCIENCE LETTERS

Effects of Exogenous Galanin on Neuropathic Pain State and Change of Galanin and Its Receptors in DRG and SDH after Sciatic Nerve-Pinch Injury in Rat

(2012) Xiaofeng Xu et al.   PLoS One

The effects of galanin on dorsal root ganglion neurons with high glucose treatment in vitro

(2011) Xiaofeng Xu et al.   BRAIN RESEARCH BULLETIN

Notch Signal Suppresses Toll-like Receptor-triggered Inflammatory Responses in Macrophages by Inhibiting Extracellular Signal-regulated Kinase 1/2-mediated Nuclear Factor κB Activation

(2011) Qinghua Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-like receptors in neurodegeneration

(2008) Eitan Okun et al.   BRAIN RESEARCH REVIEWS