Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol

Mitochondrial Biogenesis as a Pharmacological Target: A New Approach to Acute and Chronic Diseases

(2016) Ryan M. Whitaker et al.   Annual Review of Pharmacology and Toxicology

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

(2016) Christopher D. Wiley et al.   Cell Metabolism

Short-Chain Fatty Acid Acetate Stimulates Adipogenesis and Mitochondrial Biogenesis via GPR43 in Brown Adipocytes

(2016) Jiamiao Hu et al.   ENDOCRINOLOGY

Mitochondrial biogenesis and clearance: a balancing act

(2016) Christina Ploumi et al.   FEBS Journal

Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases

(2016) Robert B. Cameron et al.   JOURNAL OF MEDICINAL CHEMISTRY

G Protein–Coupled Receptor-G–Proteinβγ–Subunit Signaling Mediates Renal Dysfunction and Fibrosis in Heart Failure

(2016) Fadia A. Kamal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis

(2016) P Fortini et al.   Cell Death & Disease

Depletion of mitoferrins leads to mitochondrial dysfunction and impairment of adipogenic differentiation in 3T3-L1 preadipocytes

(2015) Y.-C. Chen et al.   FREE RADICAL RESEARCH

mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis

(2015) Yi Bao et al.   JOURNAL OF CELL BIOLOGY

Synergistic neuroprotection by epicatechin and quercetin: Activation of convergent mitochondrial signaling pathways

(2015) M. Nichols et al.   NEUROSCIENCE

Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux

(2015) Laura C. O'Brien et al.   STEM CELLS AND DEVELOPMENT

Formoterol Restores Mitochondrial and Renal Function after Ischemia-Reperfusion Injury

(2014) S. R. Jesinkey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile

(2013) Evi M. Mercken et al.   AGING CELL

Mitochondrial quality control and communications with the nucleus are important in maintaining mitochondrial function and cell health

(2013) Vassilios N. Kotiadis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

β2-Adrenoceptor agonists in the regulation of mitochondrial biogenesis

(2013) Yuri K. Peterson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Dynamic Process of β2-Adrenergic Receptor Activation

(2013) Rie Nygaard et al.   CELL

Erythropoietin enhances mitochondrial biogenesis in cardiomyocytes exposed to chronic hypoxia through Akt/eNOS signalling pathway

(2013) Chuan Qin et al.   CELL BIOLOGY INTERNATIONAL

Molecular interactions between fenoterol stereoisomers and derivatives and the β2-adrenergic receptor binding site studied by docking and molecular dynamics simulations

(2013) Anita Plazinska et al.   JOURNAL OF MOLECULAR MODELING

The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor

(2013) Tae Hun Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Haploinsufficiency of Akt1 Prolongs the Lifespan of Mice

(2013) Aika Nojima et al.   PLoS One

Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1α activation following ischemia–reperfusion injury

(2013) Jason A. Funk et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sustained Activation of Akt Elicits Mitochondrial Dysfunction to Block Plasmodium falciparum Infection in the Mosquito Host

(2013) Shirley Luckhart et al.   PLoS Pathogens

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Oxidative and nitrosative stress in the maintenance of myocardial function

(2012) Yixuan Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Metabolic switching and fuel choice during T-cell differentiation and memory development

(2012) Gerritje J. W. Windt et al.   IMMUNOLOGICAL REVIEWS

Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors

(2012) James F. Blake et al.   JOURNAL OF MEDICINAL CHEMISTRY

Biased Signaling Pathways in  2-Adrenergic Receptor Characterized by 19F-NMR

(2012) J. J. Liu et al.   SCIENCE

β2-Adrenergic activity of 6-methoxykaempferol-3-O-glucoside on rat uterus: In vitro and in silico studies

(2011) Aimun A.E. Ahmed et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Multiple ligand-specific conformations of the β2-adrenergic receptor

(2011) Alem W Kahsai et al.   Nature Chemical Biology

A high-throughput respirometric assay for mitochondrial biogenesis and toxicity

(2010) Craig C. Beeson et al.   ANALYTICAL BIOCHEMISTRY

The selectivity of β-adrenoceptor agonists at human β1-, β2- and β3-adrenoceptors

(2010) Jillian G Baker   BRITISH JOURNAL OF PHARMACOLOGY

Serotonin, But Not N-Methyltryptamines, Activates the Serotonin 2A Receptor Via a  -Arrestin2/Src/Akt Signaling Complex In Vivo

(2010) C. L. Schmid et al.   JOURNAL OF NEUROSCIENCE

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

(2010) Michael P. Bokoch et al.   NATURE

Mitochondrial dynamics and apoptosis

(2008) D.-F. Suen et al.   GENES & DEVELOPMENT