Combined transcriptome and metabolome analyses of metformin effects reveal novel links between metabolic networks in steroidogenic systems
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Combined transcriptome and metabolome analyses of metformin effects reveal novel links between metabolic networks in steroidogenic systems
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-08-11
DOI
10.1038/s41598-017-09189-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs
- (2016) Bruna Corominas-Faja et al. Aging-US
- Metformin inhibits the proliferation of human prostate cancer PC-3 cells via the downregulation of insulin-like growth factor 1 receptor
- (2015) Haruo Kato et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes
- (2015) Tao Xu et al. DIABETES CARE
- Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome
- (2015) Daniel A. Dumesic et al. ENDOCRINE REVIEWS
- Premature Adrenarche - A Common Condition with Variable Presentation
- (2015) Pauliina Utriainen et al. Hormone Research in Paediatrics
- Regulation of androgen biosynthesis – A short review and preliminary results from the hyperandrogenic starvation NCI-H295R cell model
- (2015) Petra Kempná et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Antitumor effect of metformin on cholangiocarcinoma: In vitro and in vivo studies
- (2015) TAKAYUKI FUJIMORI et al. ONCOLOGY REPORTS
- 1H HR-MAS NMR Based Metabolic Profiling of Cells in Response to Treatment with a Hexacationic Ruthenium Metallaprism as Potential Anticancer Drug
- (2015) Martina Vermathen et al. PLoS One
- Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis
- (2015) Sameer S. Udhane et al. Scientific Reports
- Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis
- (2015) Takla Griss et al. PLOS BIOLOGY
- Transcriptomic analysis reveals inhibition of androgen receptor activity by AMPK in prostate cancer cells
- (2015) Sarah Jurmeister et al. Oncotarget
- C/EBPβ (CCAAT/enhancer-binding protein β) mediates progesterone production through transcriptional regulation in co-operation with SF-1 (steroidogenic factor-1)
- (2014) Tetsuya Mizutani et al. BIOCHEMICAL JOURNAL
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
- (2014) Anila K. Madiraju et al. NATURE
- Metformin—mode of action and clinical implications for diabetes and cancer
- (2014) Ida Pernicova et al. Nature Reviews Endocrinology
- Correction: Dynamic Regulation of Extracellular Signal-Regulated Kinase (ERK) by Protein Phosphatase 2A Regulatory Subunit B56γ1 in Nuclei Induces Cell Migration
- (2014) Ei Kawahara et al. PLoS One
- Phosphorylation of Human Cytochrome P450c17 by p38α Selectively Increases 17,20 Lyase Activity and Androgen Biosynthesis
- (2013) Meng Kian Tee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Melanocortin receptor accessory proteins in adrenal gland physiology and beyond
- (2013) T V Novoselova et al. JOURNAL OF ENDOCRINOLOGY
- AKR1C3 as a target in castrate resistant prostate cancer
- (2013) Adegoke O. Adeniji et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
- (2013) Russell A. Miller et al. NATURE
- Differential Regulation of Human 3β-Hydroxysteroid Dehydrogenase Type 2 for Steroid Hormone Biosynthesis by Starvation and Cyclic Amp Stimulation: Studies in the Human Adrenal NCI-H295R Cell Model
- (2013) Sameer Udhane et al. PLoS One
- Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
- (2012) Evanthia Diamanti-Kandarakis et al. ENDOCRINE REVIEWS
- Metformin Inhibits Human Androgen Production by Regulating Steroidogenic Enzymes HSD3B2 and CYP17A1 and Complex I Activity of the Respiratory Chain
- (2012) Andrea Hirsch et al. ENDOCRINOLOGY
- Expression Patterns of 17β-Hydroxysteroid Dehydrogenase 14 in Human Tissues
- (2012) T. Sivik et al. HORMONE AND METABOLIC RESEARCH
- The steroid metabolome of adrenarche
- (2012) Juilee Rege et al. JOURNAL OF ENDOCRINOLOGY
- Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome
- (2012) Yongyong Shi et al. NATURE GENETICS
- HMDB 3.0—The Human Metabolome Database in 2013
- (2012) David S. Wishart et al. NUCLEIC ACIDS RESEARCH
- Effects of mitotane on gene expression in the adrenocortical cell line NCI-H295R: a microarray study
- (2012) Adrienn Zsippai et al. PHARMACOGENOMICS
- Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA
- (2011) Atanas Kamburov et al. BIOINFORMATICS
- Metscape 2 bioinformatics tool for the analysis and visualization of metabolomics and gene expression data
- (2011) Alla Karnovsky et al. BIOINFORMATICS
- Spin echo NMR spectra without J modulation
- (2011) Juan A. Aguilar et al. CHEMICAL COMMUNICATIONS
- The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
- (2011) Walter L. Miller et al. ENDOCRINE REVIEWS
- Metformin and cancer: new applications for an old drug
- (2011) Taxiarchis V. Kourelis et al. MEDICAL ONCOLOGY
- Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the Chemosensitivity of Tumour Cells
- (2011) Rachel Cavill et al. PLoS Computational Biology
- Metscape: a Cytoscape plug-in for visualizing and interpreting metabolomic data in the context of human metabolic networks
- (2010) Jing Gao et al. BIOINFORMATICS
- Impact of Differential P450c17 Phosphorylation by cAMP Stimulation and by Starvation Conditions on Enzyme Activities and Androgen Production in NCI-H295R Cells
- (2010) Petra Kempná et al. ENDOCRINOLOGY
- Effects of methoxychlor and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase-3 activities in human and rat testes
- (2010) G.-X. Hu et al. INTERNATIONAL JOURNAL OF ANDROLOGY
- Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
- (2010) Marc Foretz et al. JOURNAL OF CLINICAL INVESTIGATION
- Prognostic relevance of CCN3 in Ewing sarcoma
- (2009) Bernard Perbal et al. HUMAN PATHOLOGY
- Cyclic regulation of transcription factor C/EBP beta in human endometrium
- (2009) Beth J Plante et al. Reproductive Biology and Endocrinology
- G Protein-Coupled Receptors Go Extracellular: RhoA Integrates the Integrins
- (2008) C. T. Walsh et al. MOLECULAR INTERVENTIONS
- Androgen synthesis in adrenarche
- (2008) Walter L. Miller REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Drug Insight: insulin-sensitizing drugs in the treatment of polycystic ovary syndrome—a reappraisal
- (2008) Andrea Dunaif Nature clinical practice. Endocrinology & metabolism
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started