Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague–Dawley rats

Different immune cells mediate mechanical pain hypersensitivity in male and female mice

(2015) Robert E Sorge et al.   NATURE NEUROSCIENCE

Fractalkine/CX3CR1 signaling during neuropathic pain

(2014) Anna K. Clark et al.   Frontiers in Cellular Neuroscience

The role of MAC1 in diesel exhaust particle-induced microglial activation and loss of dopaminergic neuron function

(2013) Shannon Levesque et al.   JOURNAL OF NEUROCHEMISTRY

Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy

(2013) Magdalena Zychowska et al.   JOURNAL OF NEUROIMMUNOLOGY

Blockade of Toll-Like Receptor 4 Attenuates Morphine Tolerance and Facilitates the Pain Relieving Properties of Morphine

(2013) L. N. Eidson et al.   JOURNAL OF NEUROSCIENCE

Persistent Peripheral Inflammation Attenuates Morphine-Induced Periaqueductal Gray Glial Cell Activation and Analgesic Tolerance in the Male Rat

(2013) Lori N. Eidson et al.   JOURNAL OF PAIN

Spinal Endomorphin 2 Antinociception and the Mechanisms That Produce It Are Both Sex- and Stage of Estrus Cycle–Dependent in Rats

(2013) Nai-Jiang Liu et al.   JOURNAL OF PAIN

A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4

(2013) Leandro F.S. Bastos et al.   NEUROSCIENCE LETTERS

Minocycline selectively inhibits M1 polarization of microglia

(2013) K Kobayashi et al.   Cell Death & Disease

Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement

(2012) M. R. Hutchinson et al.   JOURNAL OF NEUROSCIENCE

Morphine activates neuroinflammation in a manner parallel to endotoxin

(2012) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats

(2012) Lisa C. Loram et al.   PSYCHONEUROENDOCRINOLOGY

Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity

(2011) Shannon Levesque et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease

(2011) Mibel M Pabon et al.   Journal of Neuroinflammation

Spinal Synthesis of Estrogen and Concomitant Signaling by Membrane Estrogen Receptors Regulate Spinal  - and  -Opioid Receptor Heterodimerization and Female-Specific Spinal Morphine Antinociception

(2011) N.-J. Liu et al.   JOURNAL OF NEUROSCIENCE

Early-Life Experience Decreases Drug-Induced Reinstatement of Morphine CPP in Adulthood via Microglial-Specific Epigenetic Programming of Anti-Inflammatory IL-10 Expression

(2011) J. M. Schwarz et al.   JOURNAL OF NEUROSCIENCE

Microglia and Memory: Modulation by Early-Life Infection

(2011) L. L. Williamson et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

(2011) R. E. Sorge et al.   JOURNAL OF NEUROSCIENCE

Ventromedial and medial preoptic hypothalamic ibotenic acid lesions potentiate systemic morphine analgesia in female, but not male rats

(2010) Giuseppe Cataldo et al.   BEHAVIOURAL BRAIN RESEARCH

Formation of  -/ -opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia

(2010) S. Chakrabarti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex Differences in Minocycline-Induced Neuroprotection after Experimental Stroke

(2009) Jun Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The “Toll” of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia

(2009) Linda R. Watkins et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia

(2008) Mark R. Hutchinson et al.   BRAIN BEHAVIOR AND IMMUNITY

Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia

(2008) Mark R. Hutchinson et al.   BRAIN BEHAVIOR AND IMMUNITY

Sexually dimorphic activation of the periaqueductal gray–rostral ventromedial medullary circuit during the development of tolerance to morphine in the rat

(2008) Dayna R. Loyd et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)

(2008) Mark R. Hutchinson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glia in pathological pain: A role for fractalkine

(2008) E.D. Milligan et al.   JOURNAL OF NEUROIMMUNOLOGY

Sex Differences in  -Opioid Receptor Expression in the Rat Midbrain Periaqueductal Gray Are Essential for Eliciting Sex Differences in Morphine Analgesia

(2008) D. R. Loyd et al.   JOURNAL OF NEUROSCIENCE

Methamphetamine Causes Microglial Activation in the Brains of Human Abusers

(2008) Y. Sekine et al.   JOURNAL OF NEUROSCIENCE

Relationship of Spinal Dynorphin Neurons to  -Opioid Receptors and Estrogen Receptor  : Anatomical Basis for Ovarian Sex Steroid Opioid Antinociception

(2008) A. R. Gintzler et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS