HIF-1-mediated suppression of mitochondria electron transport chain function confers resistance to lidocaine-induced cell death

Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype

(2016) Gregg L Semenza   EMBO JOURNAL

Mitochondrial disease therapy from thin air?

(2016) E. A. Shoubridge   SCIENCE

Hypoxia as a therapy for mitochondrial disease

(2016) I. H. Jain et al.   SCIENCE

VHL-deficient renal cancer cells gain resistance to mitochondria-activating apoptosis inducers by activating AKT through the IGF1R-PI3K pathway

(2016) Ryuji Yamaguchi et al.   TUMOR BIOLOGY

HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity

(2016) Hiroaki Semba et al.   Nature Communications

Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner

(2016) Hiroki Daijo et al.   Scientific Reports

The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells

(2016) Akihisa Okamoto et al.   BMC Anesthesiology

HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs

(2014) Tao Zhao et al.   Scientific Reports

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Hydrogen Sulfide Inhibits Hypoxia- But Not Anoxia-Induced Hypoxia-Inducible Factor 1 Activation in a von Hippel-Lindau- and Mitochondria-Dependent Manner

(2011) Shinichi Kai et al.   ANTIOXIDANTS & REDOX SIGNALING

Ensembl BioMarts: a hub for data retrieval across taxonomic space

(2011) R. J. Kinsella et al.   Database-The Journal of Biological Databases and Curation

HIF-1 and HIF-2 transcription factors — Similar but not identical

(2010) Agnieszka Loboda et al.   MOLECULES AND CELLS

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Persisting mild hypothermia suppresses hypoxia-inducible factor-1α protein synthesis and hypoxia-inducible factor-1-mediated gene expression

(2009) Tomoharu Tanaka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Intermittent Hypoxia-Mediated Plasticity of Acute O2 Sensing Requires Altered Red-Ox Regulation by HIF-1 and HIF-2

(2009) Nanduri R. Prabhakar et al.   Annals of the New York Academy of Sciences

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Apoptosis induction by different local anaesthetics in a neuroblastoma cell line

(2009) R. Werdehausen et al.   BRITISH JOURNAL OF ANAESTHESIA

n-Propyl gallate activates hypoxia-inducible factor 1 by modulating intracellular oxygen-sensing systems

(2008) Motohide Kimura et al.   BIOCHEMICAL JOURNAL

Hypoxic reprogramming

(2008) Daniel P Kelly   NATURE GENETICS

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

(2008) Julián Aragonés et al.   NATURE GENETICS