Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner

Cigarette smoke-mediated oxidative stress induces apoptosis via the MAPKs/STAT1 pathway in mouse lung fibroblasts

(2016) Hanbyeol Lee et al.   TOXICOLOGY LETTERS

The volatile anesthetic isoflurane differentially suppresses the induction of erythropoietin synthesis elicited by acute anemia and systemic hypoxemia in mice in an hypoxia-inducible factor-2-dependent manner

(2014) Shinichi Kai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Global Effects of Smoking, of Quitting, and of Taxing Tobacco

(2014) Prabhat Jha et al.   NEW ENGLAND JOURNAL OF MEDICINE

p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice

(2014) Satoshi Marumo et al.   BMC Pulmonary Medicine

Differential roles of prostaglandin E-type receptors in activation of hypoxia-inducible factor 1 by prostaglandin E1in vascular-derived cells under non-hypoxic conditions

(2013) Kengo Suzuki et al.   PeerJ

Mitochondrial reactive oxygen species mediates nicotine-induced hypoxia-inducible factor-1α expression in human non-small cell lung cancer cells

(2012) Lili Guo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics

(2012) Y Kanda   BONE MARROW TRANSPLANTATION

Hydrogen Sulfide Inhibits Hypoxia- But Not Anoxia-Induced Hypoxia-Inducible Factor 1 Activation in a von Hippel-Lindau- and Mitochondria-Dependent Manner

(2011) Shinichi Kai et al.   ANTIOXIDANTS & REDOX SIGNALING

Chronic CSE Treatment Induces the Growth of Normal Oral Keratinocytes via PDK2 Upregulation, Increased Glycolysis and HIF1α Stabilization

(2011) Wenyue Sun et al.   PLoS One

General Anesthetics Inhibit Erythropoietin Induction under Hypoxic Conditions in the Mouse Brain

(2011) Tomoharu Tanaka et al.   PLoS One

Hypoxia inducible factor-1  in human emphysema lung tissue

(2010) M. Yasuo et al.   EUROPEAN RESPIRATORY JOURNAL

Edaravone directly reacts with singlet oxygen and protects cells from attack

(2010) Yoko Nishinaka et al.   LIFE SCIENCES

Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species

(2010) David A. Patten et al.   MOLECULAR BIOLOGY OF THE CELL

Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke–induced pulmonary injury and emphysema

(2010) Toshinori Yoshida et al.   NATURE MEDICINE

Cigarette smoke extract induces COX-2 expression via a PKCα/c-Src/EGFR, PDGFR/PI3K/Akt/NF-κB pathway and p300 in tracheal smooth muscle cells

(2009) Chuen-Mao Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in human tracheal smooth muscle cells

(2009) Shin-Ei Cheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cigarette Smoke Induces Cellular Senescence via Werner's Syndrome Protein Down-regulation

(2008) Toru Nyunoya et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manner

(2008) Kenichiro Nishi et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species and HIF-1 signalling in cancer

(2008) Alex Galanis et al.   CANCER LETTERS

Induction of apoptosis by cigarette smoke via ROS-dependent endoplasmic reticulum stress and CCAAT/enhancer-binding protein-homologous protein (CHOP)

(2008) Yasuhiro Tagawa et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Akt/mTOR Pathway Assures the Synthesis of HIF-1α Protein in a Glucose- and Reoxygenation-dependent Manner in Irradiated Tumors

(2008) Hiroshi Harada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anticancer Photodynamic and Non-photodynamic Effects of Pterin Derivatives on a Pancreatic Cancer Cell Line

(2008) Takashi Miyoshi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Thioredoxin-1 Ameliorates Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

(2008) A. Sato et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Macrophage Migration Inhibitory Factor Activates Hypoxia-Inducible Factor in a p53-Dependent Manner

(2008) Seiko Oda et al.   PLoS One