Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways

Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

(2016) Johanna Michl et al.   EMBO JOURNAL

The TIP60 Complex Is a Conserved Coactivator of HIF1A

(2016) Joel I. Perez-Perri et al.   Cell Reports

Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins

(2016) Gaspar J. Kitange et al.   Cell Reports

Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells

(2015) Emilie Renaud et al.   NUCLEIC ACIDS RESEARCH

Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma

(2015) Wen-Pin Su et al.   Oncotarget

Metal-based anticancer chemotherapeutic agents

(2014) Nafees Muhammad et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair

(2014) Michael R.G. Hodskinson et al.   MOLECULAR CELL

Rational design and validation of a Tip60 histone acetyltransferase inhibitor

(2014) Chunxia Gao et al.   Scientific Reports

KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling

(2013) Abderrahmane Kaidi et al.   NATURE

BRCA1: A Missing Link in the Fanconi Anemia/BRCA Pathway

(2013) Alan D. D'Andrea   Cancer Discovery

Stabilization of p21 (Cip1/WAF1) following Tip60-dependent acetylation is required for p21-mediated DNA damage response

(2012) M-S Lee et al.   CELL DEATH AND DIFFERENTIATION

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

(2012) H. Kim et al.   GENES & DEVELOPMENT

Regulation of Rev1 by the Fanconi anemia core complex

(2012) Hyungjin Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterisation of a Tip60 Specific Inhibitor, NU9056, in Prostate Cancer

(2012) Kelly Coffey et al.   PLoS One

Activation of a Tip60/E2F1/ERCC1 network in human lung adenocarcinoma cells exposed to cisplatin

(2011) Arnaud Van Den Broeck et al.   CARCINOGENESIS

Novel Phosphoinositide 3-Kinase/mTOR Dual Inhibitor, NVP-BGT226, Displays Potent Growth-Inhibitory Activity against Human Head and Neck Cancer Cells In Vitro and In Vivo

(2011) K.-Y. Chang et al.   CLINICAL CANCER RESEARCH

6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site

(2011) Massimo Ghizzoni et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells

(2011) Qi-En Wang et al.   Molecular Cancer

SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype

(2011) Chantal Stoepker et al.   NATURE GENETICS

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

(2011) Gerry P Crossan et al.   NATURE GENETICS

Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication

(2011) Koji Nakanishi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair

(2011) D. T. Long et al.   SCIENCE

Expanded roles of the Fanconi anemia pathway in preserving genomic stability

(2010) Y. Kee et al.   GENES & DEVELOPMENT

Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

(2010) T. G. Oliver et al.   GENES & DEVELOPMENT

Genetic inactivation of the Fanconi anemia gene FANCC identified in the hepatocellular carcinoma cell line HuH-7 confers sensitivity towards DNA-interstrand crosslinking agents

(2010) Andreas Palagyi et al.   Molecular Cancer

Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation

(2010) Junya Kobayashi et al.   Molecular Cancer

MHF1-MHF2, a Histone-Fold-Containing Protein Complex, Participates in the Fanconi Anemia Pathway via FANCM

(2010) Thiyam Ramsing Singh et al.   MOLECULAR CELL

A Histone-Fold Complex and FANCM Form a Conserved DNA-Remodeling Complex to Maintain Genome Stability

(2010) Zhijiang Yan et al.   MOLECULAR CELL

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

A new nuclease member of the FAN club

(2010) Min Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex

(2010) Ambrose R Cole et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Suppression of Rev3, the catalytic subunit of Pol , sensitizes drug-resistant lung tumors to chemotherapy

(2010) J. Doles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair

(2009) Jennifer M. Svendsen et al.   CELL

Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases

(2009) Samira Fekairi et al.   CELL

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

(2009) Feng Zhang et al.   CURRENT BIOLOGY

Differential Roles for DNA Polymerases Eta, Zeta, and REV1 in Lesion Bypass of Intrastrand versus Interstrand DNA Cross-Links

(2009) J. K. Hicks et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural and Functional Relationships of the XPF/MUS81 Family of Proteins

(2008) Alberto Ciccia et al.   Annual Review of Biochemistry

Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair

(2008) Markus Räschle et al.   CELL

Role for DNA Polymerase κ in the Processing ofN2-N2-Guanine Interstrand Cross-links

(2008) Irina G. Minko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tip60 Is Regulated by Circadian Transcription Factor Clock and Is Involved in Cisplatin Resistance

(2008) Naoya Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tip60 Is Required for DNA Interstrand Cross-link Repair in the Fanconi Anemia Pathway

(2008) James Hejna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPα

(2008) D Bararia et al.   LEUKEMIA

FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex

(2008) Spencer J. Collis et al.   MOLECULAR CELL