Interaction of Src and Alpha-V Integrin Regulates Fibroblast Migration and Modulates Lung Fibrosis in A Preclinical Model of Lung Fibrosis

Simultaneous deactivation of FAK and Src improves the pathology of hypertrophic scar

(2016) Linlin Su et al.   Scientific Reports

Influence of cyclosporine A on glomerular growth and the effect of mizoribine and losartan on cyclosporine nephrotoxicity in young rats

(2016) Ji Hong Kim et al.   Scientific Reports

The Impact of Lung Cancer on Survival of Idiopathic Pulmonary Fibrosis

(2015) Sara Tomassetti et al.   CHEST

Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

(2015) Lutz Wollin et al.   EUROPEAN RESPIRATORY JOURNAL

S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

(2015) Pulin Che et al.   Scientific Reports

SRC: A Century of Science Brought to the Clinic

(2015) Alexey Aleshin et al.   NEOPLASIA

Pulmonary Function and Survival in Idiopathic vs Secondary Usual Interstitial Pneumonia

(2014) Matthew J. Strand et al.   CHEST

FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis

(2013) Qiang Ding et al.   AMERICAN JOURNAL OF PATHOLOGY

The Src family kinase inhibitors PP2 and PP1 effectively block TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells

(2012) Tobias Bartscht et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The mechanical memory of lung myofibroblasts

(2012) Jenna L. Balestrini et al.   Integrative Biology

FAK promotes recruitment of talin to nascent adhesions to control cell motility

(2012) Christine Lawson et al.   JOURNAL OF CELL BIOLOGY

Src kinase pathway is involved in NFAT5-mediated S100A4 induction by hyperosmotic stress in colon cancer cells

(2011) Min Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44

(2011) Yuejuan Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis

(2010) Amber L. Degryse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Targeting SRC in glioblastoma tumors and brain metastases: Rationale and preclinical studies

(2010) Manmeet S. Ahluwalia et al.   CANCER LETTERS

Phase I Safety, Pharmacokinetics, and Inhibition of Src Activity Study of Saracatinib in Patients with Solid Tumors

(2010) J. Baselga et al.   CLINICAL CANCER RESEARCH

Inhibition of Src Impairs the Growth of Met-Addicted Gastric Tumors

(2010) A. Bertotti et al.   CLINICAL CANCER RESEARCH

Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts

(2010) Guo-qiang Cai et al.   EXPERIMENTAL CELL RESEARCH

Dynamics and Mechanism of p130Cas Localization to Focal Adhesions

(2010) Dominique M. Donato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Src Inhibitor AZD0530 Blocks Invasion and May Act as a Radiosensitizer in Lung Cancer Cells

(2010) Phillip R. Purnell et al.   Journal of Thoracic Oncology

Thy-1 Attenuates TNF-α-Activated Gene Expression in Mouse Embryonic Fibroblasts via Src Family Kinase

(2010) Bin Shan et al.   PLoS One

Circulating fibronectin isoforms predict the degree of fibrosis in chronic hepatitis C

(2009) Norman J. Hackl et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Targeting Src in breast cancer

(2008) R. S. Finn   ANNALS OF ONCOLOGY

Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts

(2008) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

Requirement of HDAC6 for Transforming Growth Factor-β1-induced Epithelial-Mesenchymal Transition

(2008) Bin Shan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts

(2008) M. P. Iwanicki et al.   JOURNAL OF CELL SCIENCE

Murine models of pulmonary fibrosis

(2007) Bethany B. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly

(2007) Priscila M. F. Siesser et al.   CELL MOTILITY AND THE CYTOSKELETON