The Src family kinase inhibitors PP2 and PP1 effectively block TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells

Transforming growth factor-β signaling in tumor initiation, progression and therapy in breast cancer: an update

(2011) Xuyu Zu et al.   CELL AND TISSUE RESEARCH

Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression

(2011) Michael K. Wendt et al.   CELL AND TISSUE RESEARCH

The Src Family Kinase Inhibitors PP2 and PP1 Block TGF-Beta1-Mediated Cellular Responses by Direct and Differential Inhibition of Type I and Type II TGF-Beta Receptors

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Differential roles of Src in transforming growth factor-ß regulation of growth arrest, epithelial-to-mesenchymal transition and cell migration in pancreatic ductal adenocarcinoma cells

(2011) Ungefroren   INTERNATIONAL JOURNAL OF ONCOLOGY

Intravital Imaging Illuminates Transforming Growth Factor β Signaling Switches during Metastasis

(2010) Silvia Giampieri et al.   CANCER RESEARCH

The role of the tissue microenvironment in the regulation of cancer cell motility and invasion

(2010) Jan Brábek et al.   Cell Communication and Signaling

TGF-² Signaling and the Role of Inhibitory Smads in Non-small Cell Lung Cancer

(2010) Hyo-Sung Jeon et al.   Journal of Thoracic Oncology

Targeting the transforming growth factor-β signaling pathway in human cancer

(2009) Nagathihalli S Nagaraj et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

LY2109761, a novel transforming growth factor   receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

(2008) D. Melisi et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signaling

(2008) I Ischenko et al.   ONCOGENE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE