Tangluoning, a traditional Chinese medicine, attenuates in vivo and in vitro diabetic peripheral neuropathy through modulation of PERK/Nrf2 pathway

Rutin ameliorates diabetic neuropathy by lowering plasma glucose and decreasing oxidative stress via Nrf2 signaling pathway in rats

(2016) Ruifeng Tian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ERS-PERK signaling pathway-mediated Nrf2/ARE-HO-1 axis: A novel therapeutic target for attenuating myocardial ischemia and reperfusion injury

(2016) Jichun Wang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Paeoniflorin protects Schwann cells against high glucose induced oxidative injury by activating Nrf2/ARE pathway and inhibiting apoptosis

(2016) Xinwei Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The role of HO-1 in protection against lead-induced neurotoxicity

(2016) Xiaoyi Li et al.   NEUROTOXICOLOGY

Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury

(2016) Maritza Oñate et al.   Scientific Reports

PERK pathway is involved in oxygen-glucose-serum deprivation-induced NF-kB activation via ROS generation in spinal cord astrocytes

(2015) Jinbo Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

(2015) Sandra I. Mota et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Curcumin ameliorates testicular damage in diabetic rats by suppressing cellular stress-mediated mitochondria and endoplasmic reticulum-dependent apoptotic death

(2015) Kahkashan Rashid et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Metabolic dysfunction is restricted to the sciatic nerve in experimental diabetic neuropathy

(2015) Oliver J. Freeman et al.   DIABETES

Allicin improves endoplasmic reticulum stress-related cognitive deficits via PERK/Nrf2 antioxidative signaling pathway

(2015) Yao-Feng Zhu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The antioxidant machinery of the endoplasmic reticulum: Protection and signaling

(2015) Agnès Delaunay-Moisan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activated AMPK boosts the Nrf2/HO-1 signaling axis—A role for the unfolded protein response

(2015) Kristin Zimmermann et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative, Metabolic, and Apoptotic Responses of Schwann Cells to High Glucose Levels

(2015) Lorenzo Cinci et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Mechanism of Tang Luo Ning effect on attenuating of oxidative stress in sciatic nerve of STZ-induced diabetic rats

(2015) Xinwei Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The emerging role of redox-sensitive Nrf2–Keap1 pathway in diabetes

(2015) Elango Bhakkiyalakshmi et al.   PHARMACOLOGICAL RESEARCH

PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response

(2015) Ananya Gupta et al.   Scientific Reports

ER Stress in Diabetic Peripheral Neuropathy: A New Therapeutic Target

(2014) Phillipe D. O'Brien et al.   ANTIOXIDANTS & REDOX SIGNALING

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenite cataracts: Activation of endoplasmic reticulum stress and loss of Nrf2/Keap1-dependent stress protection

(2014) Periyasamy Palsamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

New functions of mitochondria associated membranes in cellular signaling

(2014) Alexander R. van Vliet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

l-Carnitine attenuates H2O2-induced neuron apoptosis via inhibition of endoplasmic reticulum stress

(2014) Junli Ye et al.   NEUROCHEMISTRY INTERNATIONAL

Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells

(2014) Mina Thon et al.   Scientific Reports

New directions in ER stress-induced cell death

(2013) Susan E. Logue et al.   APOPTOSIS

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Endoplasmic Reticulum Stress Plays a Key Role in the Pathogenesis of Diabetic Peripheral Neuropathy

(2013) S. Lupachyk et al.   DIABETES

Endoplasmic reticulum stress contributes to prediabetic peripheral neuropathy

(2012) Sergey Lupachyk et al.   EXPERIMENTAL NEUROLOGY

Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction

(2012) Guorui Dou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pathogenesis of diabetic neuropathy: bad to the bone

(2011) Lawrence Chan et al.   Annals of the New York Academy of Sciences

Overexpression of GRP78 protects glial cells from endoplasmic reticulum stress

(2011) Kaori Suyama et al.   NEUROSCIENCE LETTERS

Hyperglycemia magnifies Schwann cell dysfunction and cell death triggered by PA-induced lipotoxicity

(2010) Amelia Padilla et al.   BRAIN RESEARCH

Oxidative stress and dysregulation of the taurine transporter in high-glucose-exposed human Schwann cells: implications for pathogenesis of diabetic neuropathy

(2009) Trevor Askwith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Endotoxin causes functional endoplasmic reticulum failure, possibly mediated by mitochondria

(2009) Andrey V. Kozlov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

High-content screening of primary neurons: ready for prime time

(2009) Aaron Daub et al.   CURRENT OPINION IN NEUROBIOLOGY

Glucose neurotoxicity

(2007) David R. Tomlinson et al.   NATURE REVIEWS NEUROSCIENCE