Tyrosine kinase inhibitor BIBF1120 ameliorates inflammation, angiogenesis and fibrosis in CCl4-induced liver fibrogenesis mouse model

Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies

(2016) Cynthia Ju et al.   Cellular & Molecular Immunology

Crucial steps towards an effective treatment

(2016) Klaas Poelstra   Nature Reviews Gastroenterology & Hepatology

Cadherin-11 localizes to focal adhesions and promotes cell–substrate adhesion

(2016) Rahul P. Langhe et al.   Nature Communications

Liver sinusoidal endothelial cells in hepatic fibrosis

(2015) Laurie D. DeLeve   HEPATOLOGY

Inhibition of fibronectin deposition improves experimental liver fibrosis

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The interplay of the Notch signaling in hepatic stellate cells and macrophages determines the fate of liver fibrogenesis

(2015) Ruchi Bansal et al.   Scientific Reports

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

(2014) Josef Ehling et al.   GUT

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

(2014) Saravana K. Ramasamy et al.   NATURE

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(2013) Sara Lemoinne et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Notch signaling and new therapeutic options in liver disease

(2013) Carola Maria Morell et al.   JOURNAL OF HEPATOLOGY

IRF5 Is a Specific Marker of Inflammatory MacrophagesIn Vivo

(2013) Miriam Weiss et al.   MEDIATORS OF INFLAMMATION

FAK promotes recruitment of talin to nascent adhesions to control cell motility

(2012) Christine Lawson et al.   JOURNAL OF CELL BIOLOGY

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

(2012) P. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Role of Differentiation of Liver Sinusoidal Endothelial Cells in Progression and Regression of Hepatic Fibrosis in Rats

(2011) Guanhua Xie et al.   GASTROENTEROLOGY

Targeted therapy of liver fibrosis/cirrhosis and its complications

(2011) Klaas Poelstra et al.   JOURNAL OF HEPATOLOGY

Efficacy of a Tyrosine Kinase Inhibitor in Idiopathic Pulmonary Fibrosis

(2011) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing

(2010) Coert Margadant et al.   EMBO REPORTS

New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis

(2010) Yan Wang et al.   JOURNAL OF HEPATOLOGY

In Hepatic Fibrosis, Liver Sinusoidal Endothelial Cells Acquire Enhanced Immunogenicity

(2010) M. K. Connolly et al.   JOURNAL OF IMMUNOLOGY

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases

(2010) Claudia Paternostro   WORLD JOURNAL OF GASTROENTEROLOGY

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Binding of soluble fibronectin to integrin  5 1 - link to focal adhesion redistribution and contractile shape

(2008) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury

(2008) Erawan Borkham-Kamphorst et al.   LABORATORY INVESTIGATION

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(2008) Detlef Schuppan et al.   LANCET

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS

Hepatic fibrosis—Overview

(2008) Scott L. Friedman   TOXICOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY