TIGAR knockdown radiosensitizes TrxR1-overexpressing glioma in vitro and in vivo via inhibiting Trx1 nuclear transport

Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes

(2016) Junjian Wang et al.   CANCER LETTERS

Functionalized nanogels carrying an anticancer microRNA for glioblastoma therapy

(2016) Zohar Shatsberg et al.   JOURNAL OF CONTROLLED RELEASE

MDM2 antagonist nutlin-3a sensitizes tumors to V-ATPase inhibition

(2016) Lina S. Schneider et al.   Molecular Oncology

Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma

(2016) Prahlad V. Raninga et al.   Redox Biology

The thioredoxin system in breast cancer cell invasion and migration

(2016) Maneet Bhatia et al.   Redox Biology

TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of reactive oxygen species and inhibition of apoptosis

(2016) Jun-Hao Zhou et al.   Scientific Reports

Sequence analysis, expression profiles and function of thioredoxin 2 and thioredoxin reductase 1 in resistance to nucleopolyhedrovirus in Helicoverpa armigera

(2015) Songdou Zhang et al.   Scientific Reports

Radiosensitization of glioma cells by TP53-induced glycolysis and apoptosis regulator knockdown is dependent on thioredoxin-1 nuclear translocation

(2014) Haowen Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thioredoxin System in Cell Death Progression

(2012) Jun Lu et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione and Glutaredoxin Act as a Backup of Human Thioredoxin Reductase 1 to Reduce Thioredoxin 1 Preventing Cell Death by Aurothioglucose

(2012) Yatao Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells

(2011) Antonietta R. Farina et al.   FEBS LETTERS

Small molecule inhibitors of mammalian thioredoxin reductase

(2011) Wenqing Cai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Thioredoxin 1 and Thioredoxin 2 on Proliferation of Human Adipose Tissue-Derived Mesenchymal Stem Cells

(2010) Ji Sun Song et al.   STEM CELLS AND DEVELOPMENT

Modulation of intracellular ROS levels by TIGAR controls autophagy

(2009) Karim Bensaad et al.   EMBO JOURNAL

Oxidation and nuclear localization of thioredoxin-1 in sparse cell cultures

(2008) Jeanine C. Spielberger et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE